| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 102 |
Name | ADAM10 |
Synonymous | ADAM metallopeptidase domain 10;ADAM10;ADAM metallopeptidase domain 10 |
Definition | CDw156|a disintegrin and metalloprotease domain 10|disintegrin and metalloproteinase domain-containing protein 10|kuzbanian protein homolog|mammalian disintegrin-metalloprotease |
Position | 15q22 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | adam10(h) + Eve-1c(h) <==> adam10(h):Eve-1c(h) (binding) | adam10(h) + Eve-1d(h) <==> adam10(h):Eve-1d(h) (binding) | ADAM10(h) --> adam10(h) (expression). | APP(h) --adam10(h)--> alphaAPPs(h) + APP-C83(h) (processing) | N-cadherin(h) --adam10(h)--> N-cadherin-CTF1(h) + protein remnants (cleavage) | ADAM10(h) --> adam10(h) (expression). | APP770(h) --adam10(h)--> sAPP770alpha(h) + APP-C83(h) (cleavage) | HB-EGF(h) --adam10(h)--> HB-EGF-p16.4(h) + protein remnants (cleavage) | HB-EGF(h) --adam10(h)--> HB-EGF-p15(h) + protein remnants (cleavage) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 267 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 278 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 439 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 551 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 56828969 - 56830969 | Agilent_014791 |
chr15 |
Promoter: 56828969 - 56830969 | GSE27584 |
chr15 |
Promoter: 56828969 - 56830969 | Agilent_014791_44K |