| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10189 |
Name | ALYREF |
Synonymous | Aly/REF export factor;ALYREF;Aly/REF export factor |
Definition | THO complex 4|THO complex subunit 4|ally of AML-1 and LEF-1|bZIP enhancing factor|bZIP-enhancing factor BEF|tho4|transcriptional coactivator Aly/REF |
Position | 17q25.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | ALY(h) + ATP --> ALY(h){pT219} + ADP (phosphorylation) | ALY(h) + 2 ATP --AKT(m.s.)--> ALY(h){pS34}{pT219} + 2 ADP (phosphorylation) | AKT(m.s.) + ALY(h) <==> AKT(m.s.):ALY(h) (binding) | ALY(h) --> cyclinA2(h) (increase of abundance) | ALY(h) --> cyclinB1(h) (increase of abundance) | THOC4(h) --> ALY(h) (expression). | ALY(h) --> RHCE(h) (DNA binding). | THOC4(h) --> ALY(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 2 | N-acetylalanine. | Swiss-Prot 53.0 | 50 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 204 | Omega-N-methylated arginine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for ALYREF | ||