| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10146 |
Name | G3BP1 |
Synonymous | GTPase activating protein (SH3 domain) binding protein 1;G3BP1;GTPase activating protein (SH3 domain) binding protein 1 |
Definition | ATP-dependent DNA helicase VIII|G3BP-1|GAP SH3 domain-binding protein 1|GAP binding protein|Ras-GTPase-activating protein SH3-domain-binding protein|RasGAP-associated endoribonuclease G3BP|ras GTPase-activating protein-binding protein 1 |
Position | 5q33.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | G3BP1(h) --> G3BP(h) (expression). | SIAHBP1(h) + G3BP(h) <==> SIAHBP1(h):G3BP(h) (binding) | akap9(h) + G3BP(h) <==> akap9(h):G3BP(h) (binding) | G3BP1(h) --> G3BP(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 149 | Phosphoserine. | Swiss-Prot 53.0 | 232 | Phosphoserine. | Swiss-Prot 53.0 | 268 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 435 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 447 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 460 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 465 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 149 | Phosphoserine | 11604510;12642610;15302935;17081983 | Phospho.ELM 6.0 | 232 | Phosphoserine | 11604510;12642610;15302935;15144186;16094384;15659 | Phospho.ELM 6.0 | 231 | Phosphoserine | 15302935;15659558 | Phospho.ELM 6.0 | 230 | Phosphoserine | 15659558 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 151130169 - 151132169 | GSE27584 |
chr5 |
Promoter: 151130169 - 151132169 | GSE27584 |
chr5 |
Promoter: 151130169 - 151132169 | Agilent_014791_44K |