| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1000 |
Name | CDH2 |
Synonymous | cadherin 2, type 1, N-cadherin (neuronal);CDH2;cadherin 2, type 1, N-cadherin (neuronal) |
Definition | N-cadherin 1|cadherin-2|calcium-dependent adhesion protein, neuronal|neural cadherin |
Position | 18q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | N-cadherin(h) --adam10(h)--> N-cadherin-CTF1(h) + protein remnants (cleavage) | N-cadherin(h) --gamma-secretase(h)--> N-cadherin-CTF2(h) + protein remnants (cleavage) | CDH2(h) --> N-cadherin(h) (expression). | N-cadherin(h) --> N-cadherin-CTF1(h) + protein remnants (cleavage) | N-cadherin(h) --gamma-secretase(h)--> N-cadherin-CTF2(h) + protein remnants (cleavage) | N-cadherin(h) --> N-cadherin-CTF2(h) + protein remnants (cleavage) | CDH2(h) --> N-cadherin(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 190 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 273 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 325 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 402 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 572 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 651 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 692 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 785 | Phosphotyrosine. | Swiss-Prot 53.0 | 852 | Phosphotyrosine (Src) | 16371504 | Phospho.ELM 6.0 | 884 | Phosphotyrosine (Src) | 16371504 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr18 |
Promoter: 24010689 - 24012689 | Agilent_014791 |
chr18 |
Promoter: 24010689 - 24012689 | GSE27584 |
chr18 |
Promoter: 24010689 - 24012689 | Agilent_014791_44K |
chr18 |
Promoter: 24010689 - 24012689 | PMID:15467763 |
chr18 |
Promoter: 24010689 - 24012689 | PMID:16367923 |