Entrez Gene

Basic Information
Gene ID	9805
Name	SCRN1
Synonymous	secernin 1;SCRN1;secernin 1
Definition	secernin-1
Position	7p14.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.293G>C; p.R98T; 7:29955227-29955227	urinary_tract; bladder	carcinoma	Substitution - Missense
c.293G>C; p.R98T; 7:29955227-29955227	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1112C>T; p.T371I; 7:29924090-29924090	skin	malignant_melanoma	Substitution - Missense
c.721A>T; p.S241C; 7:29940700-29940700	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.575C>T; p.S192L; 7:29940846-29940846	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.380T>C; p.L127S; 7:29944141-29944141	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.575C>T; p.S192L; 7:29940846-29940846	skin	malignant_melanoma	Substitution - Missense
c.46C>T; p.R16C; 7:29969022-29969022	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.46C>T; p.R16C; 7:29969022-29969022	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.46C>T; p.R16C; 7:29969022-29969022	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.485G>A; p.R162H; 7:29944036-29944036	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.22T>C; p.Y8H; 7:29969046-29969046	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.75G>A; p.G25G; 7:29968993-29968993	skin	malignant_melanoma	Substitution - coding silent
c.501G>A; p.V167V; 7:29944020-29944020	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.833G>A; p.G278E; 7:29936628-29936628	skin	malignant_melanoma	Substitution - Missense
c.365C>T; p.T122I; 7:29944156-29944156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.939C>T; p.D313D; 7:29926599-29926599	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1074C>T; p.I358I; 7:29926464-29926464	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1074C>T; p.I358I; 7:29926464-29926464	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1102C>T; p.L368L; 7:29924100-29924100	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1113C>T; p.T371T; 7:29924089-29924089	central_nervous_system; brain	glioma	Substitution - coding silent
c.1206C>A; p.F402L; 7:29923996-29923996	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.566G>A; p.S189N; 7:29940855-29940855	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.566G>A; p.S189N; 7:29940855-29940855	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.749C>T; p.T250I; 7:29936712-29936712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.691G>C; p.D231H; 7:29940730-29940730	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.90G>T; p.R30R; 7:29968978-29968978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.306C>A; p.A102A; 7:29955214-29955214	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.306C>A; p.A102A; 7:29955214-29955214	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.420T>G; p.G140G; 7:29944101-29944101	breast	carcinoma	Substitution - coding silent
c.915C>A; p.F305L; 7:29926623-29926623	skin	malignant_melanoma	Substitution - Missense
c.874C>T; p.H292Y; 7:29936587-29936587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.58G>A; p.G20S; 7:29969010-29969010	breast	carcinoma	Substitution - Missense
c.1169C>T; p.S390F; 7:29924033-29924033	skin	malignant_melanoma	Substitution - Missense
c.867G>A; p.P289P; 7:29936594-29936594	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1216_1217delGT; p.V406fs*1; 7:29923985-29923986	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.544+1G>A; p.?; 7:29943976-29943976	liver	carcinoma	Unknown
c.109G>T; p.E37*; 7:29968959-29968959	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.940G>A; p.V314I; 7:29926598-29926598	pancreas	carcinoma	Substitution - Missense
c.139G>A; p.E47K; 7:29968929-29968929	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1232A>G; p.K411R; 7:29923970-29923970	skin; extremity	malignant_melanoma	Substitution - Missense
c.220G>A; p.A74T; 7:29955300-29955300	prostate	carcinoma	Substitution - Missense
c.1210G>A; p.D404N; 7:29923992-29923992	skin	malignant_melanoma	Substitution - Missense
c.514G>T; p.G172W; 7:29944007-29944007	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.525G>A; p.W175*; 7:29943996-29943996	pancreas	carcinoma	Substitution - Nonsense
c.1188G>A; p.A396A; 7:29924014-29924014	skin	malignant_melanoma	Substitution - coding silent
c.1081G>T; p.D361Y; 7:29926457-29926457	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1219G>T; p.D407Y; 7:29923983-29923983	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.242T>C; p.M81T; 7:29955278-29955278	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.622G>C; p.A208P; 7:29940799-29940799	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1223C>T; p.T408M; 7:29923979-29923979	prostate	adenoma	Substitution - Missense
c.266G>A; p.C89Y; 7:29955254-29955254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.790G>A; p.G264R; 7:29936671-29936671	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.420T>C; p.G140G; 7:29944101-29944101	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.645G>C; p.T215T; 7:29940776-29940776	ovary	other; neoplasm	Substitution - coding silent
c.233G>T; p.G78V; 7:29955287-29955287	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.547G>A; p.G183R; 7:29940874-29940874	prostate	carcinoma	Substitution - Missense
c.1063C>T; p.R355C; 7:29926475-29926475	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.852G>T; p.Q284H; 7:29936609-29936609	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.606G>A; p.P202P; 7:29940815-29940815	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.91C>T; p.P31S; 7:29968977-29968977	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1066G>A; p.A356T; 7:29926472-29926472	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.162C>T; p.C54C; 7:29955358-29955358	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.100G>A; p.E34K; 7:29968968-29968968	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.701A>T; p.D234V; 7:29940720-29940720	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.396C>A; p.S132S; 7:29944125-29944125	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.595G>T; p.A199S; 7:29940826-29940826	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.243G>A; p.M81I; 7:29955277-29955277	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.567T>C; p.S189S; 7:29940854-29940854	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.516G>A; p.G172G; 7:29944005-29944005	skin	malignant_melanoma	Substitution - coding silent
c.309G>A; p.E103E; 7:29955211-29955211	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.486T>C; p.R162R; 7:29944035-29944035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.576G>A; p.S192S; 7:29940845-29940845	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1017G>T; p.E339D; 7:29926521-29926521	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.707G>A; p.G236D; 7:29940714-29940714	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1104G>A; p.L368L; 7:29924098-29924098	breast	carcinoma	Substitution - coding silent
c.219C>T; p.P73P; 7:29955301-29955301	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1000G>C; p.E334Q; 7:29926538-29926538	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1005T>A; p.P335P; 7:29926533-29926533	pancreas	carcinoma	Substitution - coding silent
c.1054G>A; p.E352K; 7:29926484-29926484	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.625C>G; p.Q209E; 7:29940796-29940796	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.721A>G; p.S241G; 7:29940700-29940700	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1028G>A; p.R343H; 7:29926510-29926510	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.882C>T; p.F294F; 7:29936579-29936579	skin	malignant_melanoma	Substitution - coding silent
c.143C>T; p.P48L; 7:29968925-29968925	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.143C>T; p.P48L; 7:29968925-29968925	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.682C>G; p.P228A; 7:29940739-29940739	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.706G>T; p.G236C; 7:29940715-29940715	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.381A>T; p.L127F; 7:29944140-29944140	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.55G>A; p.D19N; 7:29969013-29969013	skin	malignant_melanoma	Substitution - Missense
c.55G>A; p.D19N; 7:29969013-29969013	skin	malignant_melanoma	Substitution - Missense
c.694C>T; p.H232Y; 7:29940727-29940727	skin	malignant_melanoma	Substitution - Missense
c.651G>A; p.E217E; 7:29940770-29940770	skin	malignant_melanoma	Substitution - coding silent
c.607G>T; p.E203*; 7:29940814-29940814	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.694C>T; p.H232Y; 7:29940727-29940727	skin	malignant_melanoma	Substitution - Missense
c.651G>A; p.E217E; 7:29940770-29940770	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.484C>T; p.R162C; 7:29944037-29944037	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]