Entrez Gene

Basic Information
Gene ID	9781
Name	RNF144A
Synonymous	ring finger protein 144A;RNF144A;ring finger protein 144A
Definition	E3 ubiquitin-protein ligase RNF144A\|UbcM4-interacting protein 4\|probable E3 ubiquitin-protein ligase RNF144A\|ring finger protein 144\|ubiquitin conjugating enzyme 7 interacting protein 4\|ubiquitin-conjugating enzyme 7-interacting protein 4
Position	2p25.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.324G>T; p.R108R; 2:7020495-7020495	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.878A>G; p.*293W; 2:7039759-7039759	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Nonstop extension
c.655G>T; p.D219Y; 2:7024514-7024514	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.492C>T; p.F164F; 2:7020663-7020663	skin	malignant_melanoma	Substitution - coding silent
c.492C>T; p.F164F; 2:7020663-7020663	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.597G>A; p.A199A; 2:7024456-7024456	breast	carcinoma	Substitution - coding silent
c.384G>A; p.Q128Q; 2:7020555-7020555	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.231G>T; p.Q77H; 2:7014549-7014549	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.416G>A; p.R139H; 2:7020587-7020587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.421G>A; p.E141K; 2:7020592-7020592	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.470C>G; p.P157R; 2:7020641-7020641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.755G>A; p.G252D; 2:7039636-7039636	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.301G>C; p.E101Q; 2:7014772-7014772	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.135+2T>G; p.?; 2:6997063-6997063	skin	malignant_melanoma	Unknown
c.735G>A; p.W245*; 2:7030203-7030203	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.377G>C; p.G126A; 2:7020548-7020548	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.523A>G; p.M175V; 2:7024382-7024382	central_nervous_system; brain	glioma	Substitution - Missense
c.336G>A; p.P112P; 2:7020507-7020507	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.415C>T; p.R139C; 2:7020586-7020586	prostate	carcinoma	Substitution - Missense
c.373G>A; p.V125M; 2:7020544-7020544	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.E78K; 2:7014550-7014550	ovary	other; neoplasm	Substitution - Missense
c.410C>T; p.A137V; 2:7020581-7020581	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.167_169delAAG; p.E57delE; 2:7014485-7014487	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.853G>T; p.G285C; 2:7039734-7039734	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.666C>T; p.F222F; 2:7030134-7030134	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.872C>A; p.P291H; 2:7039753-7039753	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.246G>T; p.E82D; 2:7014717-7014717	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.276A>G; p.R92R; 2:7014747-7014747	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.817C>T; p.P273S; 2:7039698-7039698	skin	malignant_melanoma	Substitution - Missense
c.658-2A>G; p.?; 2:7030124-7030124	stomach	carcinoma; adenocarcinoma	Unknown
c.292T>A; p.F98I; 2:7014763-7014763	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.288A>G; p.L96L; 2:7014759-7014759	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.757_758insT; p.A255fs*30; 2:7039638-7039639	oesophagus; lower_third	carcinoma; adenocarcinoma	Insertion - Frameshift
c.42C>T; p.L14L; 2:6996968-6996968	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.14G>C; p.R5T; 2:6996940-6996940	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.172G>T; p.G58*; 2:7014490-7014490	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.225C>T; p.H75H; 2:7014543-7014543	skin	malignant_melanoma	Substitution - coding silent
c.438C>A; p.C146*; 2:7020609-7020609	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Nonsense
c.283A>G; p.K95E; 2:7014754-7014754	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.179A>T; p.E60V; 2:7014497-7014497	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539C>T; p.A180V; 2:7024398-7024398	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.580C>T; p.R194*; 2:7024439-7024439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.499G>A; p.G167R; 2:7020670-7020670	breast	carcinoma	Substitution - Missense
c.697C>T; p.R233W; 2:7030165-7030165	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.787G>A; p.V263M; 2:7039668-7039668	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.778C>A; p.L260M; 2:7039659-7039659	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.362A>C; p.Q121P; 2:7020533-7020533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.482C>G; p.P161R; 2:7020653-7020653	urinary_tract; bladder	carcinoma	Substitution - Missense
c.184G>T; p.A62S; 2:7014502-7014502	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.730A>G; p.I244V; 2:7030198-7030198	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.71T>C; p.L24P; 2:6996997-6996997	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.751G>A; p.V251M; 2:7039632-7039632	breast	carcinoma	Substitution - Missense
c.47C>T; p.P16L; 2:6996973-6996973	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.47C>T; p.P16L; 2:6996973-6996973	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.154G>A; p.E52K; 2:7014472-7014472	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.322C>T; p.R108W; 2:7020493-7020493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.131C>T; p.T44I; 2:6997057-6997057	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.588A>G; p.E196E; 2:7024447-7024447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.588A>G; p.E196E; 2:7024447-7024447	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.583G>C; p.D195H; 2:7024442-7024442	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.661G>A; p.D221N; 2:7030129-7030129	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.661G>A; p.D221N; 2:7030129-7030129	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.781C>T; p.L261F; 2:7039662-7039662	skin	malignant_melanoma	Substitution - Missense
c.687G>T; p.K229N; 2:7030155-7030155	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.112T>C; p.C38R; 2:6997038-6997038	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.19C>T; p.R7W; 2:6996945-6996945	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>T; p.L269L; 2:7039688-7039688	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.13A>C; p.R5R; 2:6996939-6996939	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.563G>T; p.C188F; 2:7024422-7024422	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.295G>T; p.E99*; 2:7014766-7014766	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.410C>A; p.A137D; 2:7020581-7020581	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.710G>A; p.G237D; 2:7030178-7030178	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.608G>T; p.C203F; 2:7024467-7024467	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.604A>G; p.M202V; 2:7024463-7024463	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>T; p.S144F; 2:7020602-7020602	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]