Entrez Gene

Basic Information
Gene ID	9777
Name	TM9SF4
Synonymous	transmembrane 9 superfamily protein member 4;TM9SF4;transmembrane 9 superfamily protein member 4
Definition	dinucleotide oxidase disulfide thiol exchanger 3 superfamily member 4\|transmembrane 9 superfamily member 4
Position	20q11.21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.15C>T; p.S5S; 20:32133063-32133063	stomach	adenocarcinoma	Substitution - coding silent
c.1789T>A; p.L597M; 20:32165355-32165355	skin	malignant_melanoma	Substitution - Missense
c.664G>A; p.E222K; 20:32145153-32145153	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1381G>A; p.D461N; 20:32157896-32157896	urinary_tract; bladder	carcinoma	Substitution - Missense
c.111A>G; p.L37L; 20:32136106-32136106	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.768G>T; p.M256I; 20:32145359-32145359	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1436A>G; p.Y479C; 20:32157951-32157951	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.21C>G; p.F7L; 20:32133069-32133069	liver	carcinoma	Substitution - Missense
c.21C>G; p.F7L; 20:32133069-32133069	liver	carcinoma	Substitution - Missense
c.626C>T; p.S209L; 20:32145115-32145115	skin	malignant_melanoma	Substitution - Missense
c.762G>T; p.L254L; 20:32145353-32145353	breast	carcinoma	Substitution - coding silent
c.626C>T; p.S209L; 20:32145115-32145115	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1367G>A; p.R456Q; 20:32157882-32157882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1877G>C; p.*626S; 20:32165443-32165443	urinary_tract; bladder	carcinoma	Nonstop extension
c.621G>C; p.K207N; 20:32145110-32145110	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.621G>C; p.K207N; 20:32145110-32145110	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1229T>C; p.I410T; 20:32155137-32155137	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1431G>A; p.R477R; 20:32157946-32157946	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.475A>G; p.K159E; 20:32141893-32141893	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.226C>A; p.L76I; 20:32141544-32141544	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1249T>C; p.F417L; 20:32155157-32155157	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.378G>A; p.R126R; 20:32141796-32141796	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1869G>A; p.K623K; 20:32165435-32165435	skin	malignant_melanoma	Substitution - coding silent
c.561C>T; p.V187V; 20:32143065-32143065	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1675G>A; p.G559R; 20:32161312-32161312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1102C>T; p.L368F; 20:32150687-32150687	skin	malignant_melanoma	Substitution - Missense
c.1191C>T; p.F397F; 20:32150872-32150872	liver	carcinoma	Substitution - coding silent
c.1191C>T; p.F397F; 20:32150872-32150872	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1228A>C; p.I410L; 20:32155136-32155136	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1719C>T; p.F573F; 20:32161356-32161356	breast	carcinoma	Substitution - coding silent
c.1719C>T; p.F573F; 20:32161356-32161356	skin	malignant_melanoma	Substitution - coding silent
c.406G>A; p.D136N; 20:32141824-32141824	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.721-5G>T; p.?; 20:32145307-32145307	liver	carcinoma	Unknown
c.721-5G>T; p.?; 20:32145307-32145307	liver	carcinoma	Unknown
c.1741G>A; p.E581K; 20:32165307-32165307	thyroid	carcinoma	Substitution - Missense
c.369G>T; p.V123V; 20:32141787-32141787	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1661A>G; p.N554S; 20:32161298-32161298	liver	carcinoma	Substitution - Missense
c.1661A>G; p.N554S; 20:32161298-32161298	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1482C>T; p.F494F; 20:32158478-32158478	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1144C>T; p.R382C; 20:32150825-32150825	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.865C>T; p.R289W; 20:32146817-32146817	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.61G>A; p.D21N; 20:32133109-32133109	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1029C>G; p.I343M; 20:32149759-32149759	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1339G>A; p.V447I; 20:32157854-32157854	thyroid	carcinoma	Substitution - Missense
c.1061C>T; p.S354L; 20:32150646-32150646	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.453G>T; p.R151R; 20:32141871-32141871	breast	carcinoma	Substitution - coding silent
c.598G>T; p.E200*; 20:32143102-32143102	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1861G>A; p.A621T; 20:32165427-32165427	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.32G>T; p.G11V; 20:32133080-32133080	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1228A>G; p.I410V; 20:32155136-32155136	central_nervous_system; brain	glioma	Substitution - Missense
c.482A>G; p.Y161C; 20:32142986-32142986	skin	malignant_melanoma	Substitution - Missense
c.775G>A; p.V259I; 20:32145366-32145366	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.705C>T; p.Y235Y; 20:32145194-32145194	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.583C>T; p.Q195*; 20:32143087-32143087	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1059G>A; p.L353L; 20:32150644-32150644	pancreas	carcinoma	Substitution - coding silent
c.123C>A; p.Y41*; 20:32136118-32136118	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.1612A>G; p.M538V; 20:32160085-32160085	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1608C>T; p.I536I; 20:32160081-32160081	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.798C>A; p.I266I; 20:32145389-32145389	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.120A>G; p.E40E; 20:32136115-32136115	central_nervous_system; brain	glioma	Substitution - coding silent
c.1145G>A; p.R382H; 20:32150826-32150826	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1145G>A; p.R382H; 20:32150826-32150826	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1412G>A; p.R471Q; 20:32157927-32157927	pancreas	carcinoma	Substitution - Missense
c.1239A>G; p.V413V; 20:32155147-32155147	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1541A>G; p.Y514C; 20:32160014-32160014	liver	carcinoma	Substitution - Missense
c.1541A>G; p.Y514C; 20:32160014-32160014	liver	carcinoma	Substitution - Missense
c.1759C>T; p.L587F; 20:32165325-32165325	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.895G>T; p.D299Y; 20:32146847-32146847	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1195A>T; p.T399S; 20:32155103-32155103	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.305G>A; p.R102Q; 20:32141623-32141623	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1236C>T; p.F412F; 20:32155144-32155144	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.806C>T; p.S269F; 20:32145397-32145397	skin	malignant_melanoma	Substitution - Missense
c.958delC; p.Q322fs*4; 20:32149688-32149688	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.571G>A; p.E191K; 20:32143075-32143075	skin	malignant_melanoma	Substitution - Missense
c.520C>T; p.R174W; 20:32143024-32143024	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.41C>A; p.P14H; 20:32133089-32133089	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.271A>G; p.N91D; 20:32141589-32141589	skin	malignant_melanoma	Substitution - Missense
c.1408_1419del12; p.R471_P474delRQIP; 20:32157923-32157934	skin	malignant_melanoma	Deletion - In frame
c.397C>A; p.R133R; 20:32141815-32141815	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1408_1419del12; p.R471_P474delRQIP; 20:32157923-32157934	skin	malignant_melanoma	Deletion - In frame
c.861C>T; p.T287T; 20:32146813-32146813	skin	malignant_melanoma	Substitution - coding silent
c.1338C>T; p.L446L; 20:32157853-32157853	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1288C>T; p.P430S; 20:32157803-32157803	skin	malignant_melanoma	Substitution - Missense
c.1288C>T; p.P430S; 20:32157803-32157803	skin	malignant_melanoma	Substitution - Missense
c.720+1G>A; p.?; 20:32145210-32145210	breast	carcinoma	Unknown
c.1609G>A; p.V537I; 20:32160082-32160082	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.878C>T; p.A293V; 20:32146830-32146830	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.266A>G; p.Q89R; 20:32141584-32141584	liver	carcinoma	Substitution - Missense
c.266A>G; p.Q89R; 20:32141584-32141584	liver	carcinoma	Substitution - Missense
c.1629G>T; p.L543L; 20:32160102-32160102	skin	malignant_melanoma	Substitution - coding silent
c.1553G>T; p.G518V; 20:32160026-32160026	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1033A>T; p.I345F; 20:32149763-32149763	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.60C>T; p.N20N; 20:32133108-32133108	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1349G>T; p.G450V; 20:32157864-32157864	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1394G>A; p.R465H; 20:32157909-32157909	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1527G>A; p.W509*; 20:32160000-32160000	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.21C>T; p.F7F; 20:32133069-32133069	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.199C>T; p.R67W; 20:32141517-32141517	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1359C>T; p.F453F; 20:32157874-32157874	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1497C>T; p.I499I; 20:32158493-32158493	skin	malignant_melanoma	Substitution - coding silent
c.313G>A; p.A105T; 20:32141631-32141631	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1519-1G>A; p.?; 20:32159991-32159991	skin	malignant_melanoma	Unknown
c.273C>A; p.N91K; 20:32141591-32141591	skin	malignant_melanoma	Substitution - Missense
c.1281G>A; p.V427V; 20:32157796-32157796	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1236C>G; p.F412L; 20:32155144-32155144	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1334C>T; p.P445L; 20:32157849-32157849	skin	malignant_melanoma	Substitution - Missense
c.1481T>C; p.F494S; 20:32158477-32158477	breast	carcinoma	Substitution - Missense
c.32G>A; p.G11E; 20:32133080-32133080	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1328C>T; p.S443F; 20:32157843-32157843	skin	malignant_melanoma	Substitution - Missense
c.1430G>A; p.R477Q; 20:32157945-32157945	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1347G>T; p.L449F; 20:32157862-32157862	skin	malignant_melanoma	Substitution - Missense
c.570C>T; p.F190F; 20:32143074-32143074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.957_958insC; p.Q322fs*140; 20:32149687-32149688	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.741C>T; p.A247A; 20:32145332-32145332	skin	malignant_melanoma	Substitution - coding silent
c.570C>T; p.F190F; 20:32143074-32143074	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1563C>T; p.F521F; 20:32160036-32160036	skin	malignant_melanoma	Substitution - coding silent
c.847A>G; p.I283V; 20:32146799-32146799	liver	carcinoma	Substitution - Missense
c.215C>T; p.P72L; 20:32141533-32141533	skin	malignant_melanoma	Substitution - Missense
c.1801C>T; p.L601L; 20:32165367-32165367	pancreas	carcinoma	Substitution - coding silent
c.1728+2T>C; p.?; 20:32161367-32161367	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1801C>T; p.L601L; 20:32165367-32165367	pancreas	carcinoma	Substitution - coding silent
c.257T>C; p.L86P; 20:32141575-32141575	pancreas	carcinoma	Substitution - Missense
c.272A>G; p.N91S; 20:32141590-32141590	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1220delT; p.F408fs*7; 20:32155128-32155128	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.104C>T; p.T35I; 20:32136099-32136099	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1132T>G; p.F378V; 20:32150813-32150813	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1132T>G; p.F378V; 20:32150813-32150813	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.200G>A; p.R67Q; 20:32141518-32141518	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.555C>T; p.Y185Y; 20:32143059-32143059	skin	malignant_melanoma	Substitution - coding silent
c.1069A>G; p.S357G; 20:32150654-32150654	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.161A>C; p.Y54S; 20:32136156-32136156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.144G>C; p.Q48H; 20:32136139-32136139	urinary_tract; bladder	carcinoma	Substitution - Missense
c.185T>G; p.V62G; 20:32141503-32141503	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.185T>G; p.V62G; 20:32141503-32141503	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.185T>G; p.V62G; 20:32141503-32141503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.745C>T; p.R249C; 20:32145336-32145336	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1786G>C; p.V596L; 20:32165352-32165352	ovary	carcinoma; serous_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]