Entrez Gene

Basic Information
Gene ID	975
Name	CD81
Synonymous	CD81 molecule;CD81;CD81 molecule
Definition	26 kDa cell surface protein TAPA-1\|CD81 antigen\|CD81 antigen (target of antiproliferative antibody 1)\|tetraspanin-28\|tspan-28
Position	11p15.5
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.459G>A; p.T153T; 11:2395520-2395520	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.458C>T; p.T153M; 11:2395519-2395519	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.655G>A; p.E219K; 11:2396810-2396810	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.703G>A; p.V235M; 11:2396858-2396858	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.11A>G; p.E4G; 11:2377560-2377560	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.639T>C; p.A213A; 11:2396705-2396705	thyroid	other; neoplasm	Substitution - coding silent
c.308C>T; p.A103V; 11:2395000-2395000	skin	malignant_melanoma	Substitution - Missense
c.226G>C; p.G76R; 11:2394139-2394139	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.280-1G>A; p.?; 11:2394971-2394971	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.194T>G; p.L65R; 11:2394107-2394107	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.214A>G; p.M72V; 11:2394127-2394127	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.78C>G; p.G26G; 11:2390423-2390423	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.607T>C; p.Y203H; 11:2396673-2396673	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.479G>T; p.S160I; 11:2395888-2395888	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.42C>T; p.L14L; 11:2377591-2377591	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.614T>A; p.I205N; 11:2396680-2396680	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.450C>T; p.F150F; 11:2395511-2395511	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.222C>T; p.F74F; 11:2394135-2394135	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.409G>A; p.D137N; 11:2395470-2395470	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.107G>A; p.R36H; 11:2390452-2390452	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.193C>G; p.L65V; 11:2394106-2394106	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.470G>T; p.C157F; 11:2395879-2395879	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.208G>A; p.A70T; 11:2394121-2394121	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.229T>G; p.F77V; 11:2394142-2394142	skin	malignant_melanoma	Substitution - Missense
c.372G>A; p.K124K; 11:2395433-2395433	liver	carcinoma	Substitution - coding silent
c.372G>A; p.K124K; 11:2395433-2395433	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.531G>A; p.S177S; 11:2395940-2395940	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.531G>A; p.S177S; 11:2395940-2395940	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]