Entrez Gene

Basic Information
Gene ID	950
Name	SCARB2
Synonymous	scavenger receptor class B, member 2;SCARB2;scavenger receptor class B, member 2
Definition	85 kDa lysosomal membrane sialoglycoprotein\|85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2\|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)\|CD36 antigen-like 2\|LIMP I
Position	4q21.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.226C>A; p.L76I; 4:76195756-76195756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.262C>T; p.P88S; 4:76195720-76195720	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1169A>G; p.K390R; 4:76168421-76168421	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.903A>G; p.I301M; 4:76174235-76174235	liver	carcinoma	Substitution - Missense
c.182A>G; p.Y61C; 4:76195800-76195800	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.903A>G; p.I301M; 4:76174235-76174235	liver	carcinoma	Substitution - Missense
c.499C>T; p.L167F; 4:76179630-76179630	pancreas	carcinoma	Substitution - Missense
c.172C>G; p.L58V; 4:76195810-76195810	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.523G>A; p.E175K; 4:76179606-76179606	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1128C>T; p.I376I; 4:76168462-76168462	breast	carcinoma	Substitution - coding silent
c.1021C>T; p.H341Y; 4:76169959-76169959	prostate	carcinoma	Substitution - Missense
c.1430G>A; p.R477Q; 4:76161720-76161720	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1430G>A; p.R477Q; 4:76161720-76161720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1358T>G; p.F453C; 4:76163265-76163265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.511C>G; p.H171D; 4:76179618-76179618	breast	carcinoma	Substitution - Missense
c.612+8G>T; p.?; 4:76179509-76179509	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1428T>G; p.I476M; 4:76161722-76161722	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.457A>G; p.R153G; 4:76179672-76179672	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1194G>T; p.T398T; 4:76166295-76166295	skin	malignant_melanoma	Substitution - coding silent
c.447G>A; p.V149V; 4:76179682-76179682	breast	carcinoma	Substitution - coding silent
c.501C>G; p.L167L; 4:76179628-76179628	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.769C>T; p.H257Y; 4:76175846-76175846	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.362G>A; p.R121Q; 4:76181015-76181015	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.217G>C; p.E73Q; 4:76195765-76195765	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.23C>T; p.T8M; 4:76213521-76213521	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1183T>G; p.F395V; 4:76168407-76168407	pancreas	carcinoma	Substitution - Missense
c.84C>G; p.V28V; 4:76213460-76213460	ovary	other; neoplasm	Substitution - coding silent
c.1310A>G; p.N437S; 4:76163313-76163313	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.230G>A; p.R77K; 4:76195752-76195752	skin; leg	malignant_melanoma; superficial_spreading	Substitution - Missense
c.1332G>A; p.A444A; 4:76163291-76163291	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.625A>G; p.N209D; 4:76176516-76176516	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.437G>T; p.W146L; 4:76179692-76179692	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.800A>G; p.Y267C; 4:76175815-76175815	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1406C>T; p.A469V; 4:76161744-76161744	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1014T>A; p.S338S; 4:76169966-76169966	endometrium	carcinoma; serous_carcinoma	Substitution - coding silent
c.994+1G>A; p.?; 4:76174143-76174143	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1385G>A; p.G462E; 4:76163238-76163238	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.232G>A; p.G78R; 4:76195750-76195750	skin	malignant_melanoma	Substitution - Missense
c.1118C>T; p.T373I; 4:76168472-76168472	ovary	other; neoplasm	Substitution - Missense
c.1331C>T; p.A444V; 4:76163292-76163292	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1331C>T; p.A444V; 4:76163292-76163292	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1218C>T; p.F406F; 4:76166271-76166271	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.547G>T; p.E183*; 4:76179582-76179582	skin	malignant_melanoma	Substitution - Nonsense
c.1280C>G; p.S427C; 4:76163343-76163343	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1140C>T; p.A380A; 4:76168450-76168450	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.101A>G; p.D34G; 4:76213443-76213443	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.261_262insG; p.P88fs*18; 4:76195720-76195721	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1323C>T; p.I441I; 4:76163300-76163300	skin	malignant_melanoma	Substitution - coding silent
c.1005C>T; p.I335I; 4:76169975-76169975	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.371C>A; p.S124Y; 4:76181006-76181006	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.401G>C; p.R134T; 4:76180976-76180976	urinary_tract; bladder	carcinoma	Substitution - Missense
c.587C>A; p.S196Y; 4:76179542-76179542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.858T>C; p.S286S; 4:76174280-76174280	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1335G>C; p.L445L; 4:76163288-76163288	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.556T>A; p.S186T; 4:76179573-76179573	prostate	carcinoma	Substitution - Missense
c.824+10T>G; p.?; 4:76175781-76175781	liver	carcinoma	Unknown
c.126G>A; p.V42V; 4:76195856-76195856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1270C>T; p.R424*; 4:76163353-76163353	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.284G>T; p.R95I; 4:76181093-76181093	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1407G>A; p.A469A; 4:76161743-76161743	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.314A>G; p.N105S; 4:76181063-76181063	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.914C>T; p.T305M; 4:76174224-76174224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.914C>T; p.T305M; 4:76174224-76174224	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.469G>A; p.E157K; 4:76179660-76179660	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.469G>A; p.E157K; 4:76179660-76179660	urinary_tract; bladder	carcinoma	Substitution - Missense
c.468C>G; p.I156M; 4:76179661-76179661	breast	carcinoma	Substitution - Missense
c.453C>T; p.F151F; 4:76179676-76179676	skin	malignant_melanoma	Substitution - coding silent
c.198C>A; p.F66L; 4:76195784-76195784	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1001C>A; p.P334H; 4:76169979-76169979	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.706T>C; p.S236P; 4:76175909-76175909	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.973A>T; p.N325Y; 4:76174165-76174165	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]