| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9456 |
Name | HOMER1 |
Synonymous | homer scaffolding protein 1;HOMER1;homer scaffolding protein 1 |
Definition | homer homolog 1|homer protein homolog 1|homer, neuronal immediate early gene, 1|homer-1 |
Position | 5q14.2 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.970A>C; p.N324H; 5:79376104-79376104 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.1021A>G; p.T341A; 5:79376053-79376053 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.528-2A>T; p.?; 5:79402057-79402057 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Unknown |
c.889C>T; p.R297W; 5:79376185-79376185 |
skin | malignant_melanoma | Substitution - Missense |
c.889C>T; p.R297W; 5:79376185-79376185 |
skin | malignant_melanoma | Substitution - Missense |
c.889C>T; p.R297W; 5:79376185-79376185 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.379C>G; p.P127A; 5:79447061-79447061 |
breast | carcinoma | Substitution - Missense |
c.632G>A; p.W211*; 5:79401951-79401951 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.716C>A; p.A239E; 5:79397606-79397606 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.644T>G; p.L215R; 5:79401939-79401939 |
endometrium | carcinoma; serous_carcinoma | Substitution - Missense |
c.538A>G; p.S180G; 5:79402045-79402045 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.26C>T; p.T9I; 5:79456998-79456998 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.847C>T; p.Q283*; 5:79396852-79396852 |
liver | carcinoma | Substitution - Nonsense |
c.847C>T; p.Q283*; 5:79396852-79396852 |
liver | carcinoma | Substitution - Nonsense |
c.968G>A; p.R323H; 5:79376106-79376106 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.492T>C; p.A164A; 5:79439045-79439045 |
lung | carcinoma; small_cell_carcinoma | Substitution - coding silent |
c.566C>A; p.T189N; 5:79402017-79402017 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.331C>T; p.R111*; 5:79447109-79447109 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.331C>T; p.R111*; 5:79447109-79447109 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.424C>T; p.P142S; 5:79439113-79439113 |
skin; extremity | malignant_melanoma | Substitution - Missense |
c.465T>C; p.D155D; 5:79439072-79439072 |
prostate | carcinoma | Substitution - coding silent |
c.388G>A; p.E130K; 5:79439149-79439149 |
skin | malignant_melanoma | Substitution - Missense |
c.897A>G; p.K299K; 5:79376177-79376177 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.688A>G; p.T230A; 5:79397634-79397634 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.63G>T; p.K21N; 5:79456961-79456961 |
thyroid | other; neoplasm | Substitution - Missense |
c.291G>A; p.S97S; 5:79450993-79450993 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.932G>A; p.R311H; 5:79376142-79376142 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.33T>C; p.A11A; 5:79456991-79456991 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.290C>T; p.S97L; 5:79450994-79450994 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.802G>T; p.E268*; 5:79396897-79396897 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.171A>T; p.I57I; 5:79451113-79451113 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.76C>T; p.P26S; 5:79456948-79456948 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.967C>T; p.R323C; 5:79376107-79376107 |
pancreas | carcinoma; acinar_carcinoma | Substitution - Missense |
c.967C>T; p.R323C; 5:79376107-79376107 |
breast | carcinoma | Substitution - Missense |
c.819A>C; p.E273D; 5:79396880-79396880 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.323_325delAAG; p.E108delE; 5:79447115-79447117 |
liver | carcinoma; hepatocellular_carcinoma | Deletion - In frame |
c.366A>G; p.E122E; 5:79447074-79447074 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.51C>G; p.D17E; 5:79456973-79456973 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.29G>A; p.R10Q; 5:79456995-79456995 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.393C>T; p.S131S; 5:79439144-79439144 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.297_298insT; p.A100fs*8; 5:79447142-79447143 |
lung | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.724G>T; p.V242L; 5:79397598-79397598 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.277G>T; p.E93*; 5:79451007-79451007 |
lung | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.58A>T; p.T20S; 5:79456966-79456966 |
thyroid | carcinoma | Substitution - Missense |
c.635A>G; p.K212R; 5:79401948-79401948 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.820A>G; p.I274V; 5:79396879-79396879 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.820A>G; p.I274V; 5:79396879-79396879 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.820A>G; p.I274V; 5:79396879-79396879 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.948G>A; p.Q316Q; 5:79376126-79376126 |
skin | malignant_melanoma | Substitution - coding silent |
c.991G>A; p.E331K; 5:79376083-79376083 |
skin | malignant_melanoma | Substitution - Missense |
c.650C>T; p.A217V; 5:79401933-79401933 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.796G>A; p.E266K; 5:79396903-79396903 |
skin | malignant_melanoma | Substitution - Missense |
c.1030C>T; p.R344*; 5:79376044-79376044 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.332G>T; p.R111L; 5:79447108-79447108 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1041G>T; p.L347F; 5:79376033-79376033 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.711C>T; p.S237S; 5:79397611-79397611 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.639G>A; p.Q213Q; 5:79401944-79401944 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.639G>A; p.Q213Q; 5:79401944-79401944 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.640C>T; p.Q214*; 5:79401943-79401943 |
stomach | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.997C>A; p.L333M; 5:79376077-79376077 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.877G>A; p.E293K; 5:79376197-79376197 |
skin | malignant_melanoma | Substitution - Missense |
c.316T>G; p.F106V; 5:79447124-79447124 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.127A>C; p.N43H; 5:79456897-79456897 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1042G>A; p.A348T; 5:79376032-79376032 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.66_68delGAA; p.K22delK; 5:79456956-79456958 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Deletion - In frame |
c.683G>A; p.R228Q; 5:79401900-79401900 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.504G>A; p.Q168Q; 5:79439033-79439033 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.504G>A; p.Q168Q; 5:79439033-79439033 |
skin | malignant_melanoma | Substitution - coding silent |
c.399C>T; p.G133G; 5:79439138-79439138 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.481G>C; p.E161Q; 5:79439056-79439056 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.301G>T; p.E101*; 5:79447139-79447139 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.313G>A; p.E105K; 5:79447127-79447127 |
skin | malignant_melanoma | Substitution - Missense |