Entrez Gene

Basic Information
Gene ID	9173
Name	IL1RL1
Synonymous	interleukin 1 receptor-like 1;IL1RL1;interleukin 1 receptor-like 1
Definition	growth stimulation-expressed\|homolog of mouse growth stimulation-expressed\|interleukin 1 receptor-related protein\|interleukin-1 receptor-like 1
Position	2q12
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.581T>C; p.V194A; 2:102340799-102340799	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.805G>A; p.E269K; 2:102343158-102343158	skin	malignant_melanoma	Substitution - Missense
c.453T>A; p.C151*; 2:102340671-102340671	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.518C>A; p.T173N; 2:102340736-102340736	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.467G>A; p.G156E; 2:102340685-102340685	skin	malignant_melanoma	Substitution - Missense
c.965A>T; p.N322I; 2:102343410-102343410	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.513G>A; p.V171V; 2:102340731-102340731	skin	malignant_melanoma	Substitution - coding silent
c.525C>T; p.D175D; 2:102340743-102340743	central_nervous_system; brain	glioma	Substitution - coding silent
c.663A>C; p.E221D; 2:102342275-102342275	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.364G>A; p.V122I; 2:102340189-102340189	central_nervous_system; brain	glioma	Substitution - Missense
c.204A>G; p.S68S; 2:102338979-102338979	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.364G>A; p.V122I; 2:102340189-102340189	skin	malignant_melanoma	Substitution - Missense
c.841G>A; p.A281T; 2:102343286-102343286	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.725G>A; p.G242D; 2:102343078-102343078	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.185G>A; p.R62K; 2:102338960-102338960	skin	malignant_melanoma	Substitution - Missense
c.374C>A; p.S125*; 2:102340199-102340199	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.75G>T; p.W25C; 2:102338850-102338850	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.479G>T; p.R160M; 2:102340697-102340697	ovary	other; neoplasm	Substitution - Missense
c.436G>C; p.E146Q; 2:102340261-102340261	urinary_tract; bladder	carcinoma	Substitution - Missense
c.636A>G; p.P212P; 2:102342248-102342248	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.426A>C; p.T142T; 2:102340251-102340251	skin	malignant_melanoma	Substitution - coding silent
c.817A>T; p.N273Y; 2:102343170-102343170	skin	malignant_melanoma	Substitution - Missense
c.340C>A; p.P114T; 2:102340165-102340165	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.824+2T>G; p.?; 2:102343179-102343179	breast	carcinoma	Unknown
c.918G>A; p.L306L; 2:102343363-102343363	skin	malignant_melanoma	Substitution - coding silent
c.178C>A; p.Q60K; 2:102338953-102338953	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.643G>A; p.G215R; 2:102342255-102342255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.643G>A; p.G215R; 2:102342255-102342255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.643G>A; p.G215R; 2:102342255-102342255	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.190C>T; p.R64C; 2:102338965-102338965	skin; trunk	malignant_melanoma	Substitution - Missense
c.190C>T; p.R64C; 2:102338965-102338965	skin	malignant_melanoma	Substitution - Missense
c.88G>T; p.E30*; 2:102338863-102338863	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.58T>G; p.F20V; 2:102338322-102338322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.880G>A; p.E294K; 2:102343325-102343325	skin	malignant_melanoma	Substitution - Missense
c.501C>T; p.V167V; 2:102340719-102340719	skin	malignant_melanoma	Substitution - coding silent
c.110C>T; p.P37L; 2:102338885-102338885	skin	malignant_melanoma	Substitution - Missense
c.82G>A; p.E28K; 2:102338857-102338857	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.986G>C; p.*329S; 2:102343431-102343431	urinary_tract; bladder	carcinoma	Nonstop extension
c.661G>A; p.E221K; 2:102342273-102342273	skin	malignant_melanoma	Substitution - Missense
c.126T>C; p.P42P; 2:102338901-102338901	pancreas	carcinoma	Substitution - coding silent
c.447+2T>G; p.?; 2:102340274-102340274	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.332G>A; p.C111Y; 2:102340157-102340157	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.967C>T; p.P323S; 2:102343412-102343412	skin	malignant_melanoma	Substitution - Missense
c.260G>C; p.C87S; 2:102339035-102339035	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.216G>A; p.L72L; 2:102338991-102338991	ovary	other; neoplasm	Substitution - coding silent
c.921T>G; p.N307K; 2:102343366-102343366	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.351G>C; p.L117F; 2:102340176-102340176	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.809A>T; p.E270V; 2:102343162-102343162	skin	malignant_melanoma	Substitution - Missense
c.214C>G; p.L72V; 2:102338989-102338989	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.675G>A; p.V225V; 2:102342287-102342287	skin	malignant_melanoma	Substitution - coding silent
c.81G>A; p.L27L; 2:102338856-102338856	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.109C>T; p.P37S; 2:102338884-102338884	skin; neck	malignant_melanoma	Substitution - Missense
c.482C>T; p.A161V; 2:102340700-102340700	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.482C>T; p.A161V; 2:102340700-102340700	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.482C>T; p.A161V; 2:102340700-102340700	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.915C>T; p.A305A; 2:102343360-102343360	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.857T>A; p.V286D; 2:102343302-102343302	central_nervous_system; brain	glioma	Substitution - Missense
c.230C>T; p.A77V; 2:102339005-102339005	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.196T>C; p.F66L; 2:102338971-102338971	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.928_929GG>AA; p.G310N; 2:102343373-102343374	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.744_757del14; p.V249fs*1; 2:102343097-102343110	lung	carcinoma; large_cell_carcinoma	Deletion - Frameshift
c.386C>T; p.S129F; 2:102340211-102340211	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.881A>G; p.E294G; 2:102343326-102343326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.386C>T; p.S129F; 2:102340211-102340211	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.881A>G; p.E294G; 2:102343326-102343326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.881A>G; p.E294G; 2:102343326-102343326	large_intestine; rectum	NS	Substitution - Missense
c.967C>A; p.P323T; 2:102343412-102343412	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.233C>A; p.A78E; 2:102339008-102339008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.233C>A; p.A78E; 2:102339008-102339008	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.800A>T; p.Q267L; 2:102343153-102343153	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.970A>C; p.S324R; 2:102343415-102343415	skin	malignant_melanoma	Substitution - Missense
c.491C>T; p.S164L; 2:102340709-102340709	skin	malignant_melanoma	Substitution - Missense
c.491C>T; p.S164L; 2:102340709-102340709	skin	malignant_melanoma	Substitution - Missense
c.585G>A; p.T195T; 2:102340803-102340803	ovary	other; neoplasm	Substitution - coding silent
c.710C>A; p.A237D; 2:102343063-102343063	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.836G>A; p.G279E; 2:102343281-102343281	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.36C>T; p.L12L; 2:102338300-102338300	skin	malignant_melanoma	Substitution - coding silent
c.808G>A; p.E270K; 2:102343161-102343161	skin	malignant_melanoma	Substitution - Missense
c.257_258CC>TT; p.T86I; 2:102339032-102339033	skin	malignant_melanoma	Substitution - Missense
c.257_258CC>TT; p.T86I; 2:102339032-102339033	skin	malignant_melanoma	Substitution - Missense
c.497T>G; p.L166W; 2:102340715-102340715	skin	malignant_melanoma	Substitution - Missense
c.497T>G; p.L166W; 2:102340715-102340715	skin	malignant_melanoma	Substitution - Missense
c.767C>G; p.T256R; 2:102343120-102343120	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.227C>A; p.P76Q; 2:102339002-102339002	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.587C>T; p.A196V; 2:102340805-102340805	stomach	adenocarcinoma	Substitution - Missense
c.119G>A; p.G40E; 2:102338894-102338894	skin	malignant_melanoma	Substitution - Missense
c.655C>A; p.Q219K; 2:102342267-102342267	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.119G>A; p.G40E; 2:102338894-102338894	skin	malignant_melanoma	Substitution - Missense
c.119G>A; p.G40E; 2:102338894-102338894	skin	malignant_melanoma	Substitution - Missense
c.645A>G; p.G215G; 2:102342257-102342257	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.139G>A; p.D47N; 2:102338914-102338914	skin	malignant_melanoma	Substitution - Missense
c.787G>A; p.E263K; 2:102343140-102343140	NS	malignant_melanoma	Substitution - Missense
c.603G>A; p.T201T; 2:102340821-102340821	skin	malignant_melanoma	Substitution - coding silent
c.341_342CA>AG; p.P114Q; 2:102340166-102340167	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.15C>G; p.I5M; 2:102338279-102338279	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.460C>T; p.L154F; 2:102340678-102340678	skin	malignant_melanoma	Substitution - Missense
c.300G>A; p.A100A; 2:102340125-102340125	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.300G>A; p.A100A; 2:102340125-102340125	skin	malignant_melanoma	Substitution - coding silent
c.782T>C; p.F261S; 2:102343135-102343135	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.882A>G; p.E294E; 2:102343327-102343327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.856G>A; p.V286I; 2:102343301-102343301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.282C>T; p.F94F; 2:102340107-102340107	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]