Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9097

Name

USP14

Synonymous

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase);USP14;ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

Definition

deubiquitinating enzyme 14|tRNA-guanine transglycosylase, 60-kD subunit|ubiquitin carboxyl-terminal hydrolase 14|ubiquitin specific protease 14 (tRNA-guanine transglycosylase)|ubiquitin thioesterase 14|ubiquitin thiolesterase 14|ubiquitin-specific process

Position

18p11.32

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.371G>A; p.R124H; 18:180306-180306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1117A>C; p.K373Q; 18:204645-204645

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1342A>T; p.I448F; 18:211141-211141

 skinmalignant_melanomaSubstitution - Missense

c.560C>T; p.A187V; 18:196733-196733

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.905C>A; p.S302Y; 18:202908-202908

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.877C>T; p.R293*; 18:202880-202880

 central_nervous_system; braingliomaSubstitution - Nonsense

c.1203T>C; p.Y401Y; 18:210009-210009

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1035+10G>A; p.?; 18:203200-203200

 livercarcinomaUnknown

c.1470G>C; p.E490D; 18:211269-211269

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1036-2A>G; p.?; 18:204562-204562

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.742G>A; p.G248S; 18:198113-198113

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.574C>A; p.Q192K; 18:196747-196747

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.171T>A; p.D57E; 18:166795-166795

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.303G>A; p.M101I; 18:180238-180238

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.76C>T; p.P26S; 18:163367-163367

 skinmalignant_melanomaSubstitution - Missense

c.972G>C; p.L324F; 18:203127-203127

 skinmalignant_melanomaSubstitution - Missense

c.989G>A; p.R330Q; 18:203144-203144

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.911C>T; p.T304M; 18:202914-202914

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.797C>A; p.T266N; 18:199237-199237

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.265G>A; p.V89I; 18:179002-179002

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.689C>T; p.S230F; 18:198060-198060

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.721A>G; p.S241G; 18:198092-198092

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.721A>G; p.S241G; 18:198092-198092

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1236C>A; p.S412S; 18:210396-210396

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.723T>G; p.S241R; 18:198094-198094

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.40A>C; p.K14Q; 18:163331-163331

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.424G>A; p.A142T; 18:192861-192861

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.820C>T; p.Q274*; 18:199260-199260

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.781_783delGAA; p.E264delE; 18:199221-199223

 large_intestinecarcinoma; adenocarcinomaDeletion - In frame

c.781_783delGAA; p.E264delE; 18:199221-199223

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.781_783delGAA; p.E264delE; 18:199221-199223

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.920G>T; p.R307I; 18:202923-202923

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.1018A>C; p.N340H; 18:203173-203173

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.979C>T; p.Q327*; 18:203134-203134

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.201G>T; p.M67I; 18:178938-178938

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.207A>G; p.L69L; 18:178944-178944

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.122C>T; p.P41L; 18:163413-163413

 skin; trunkmalignant_melanomaSubstitution - Missense

c.872A>T; p.K291I; 18:199312-199312

 skinmalignant_melanomaSubstitution - Missense

c.992T>G; p.F331C; 18:203147-203147

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.631T>C; p.L211L; 18:197652-197652

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.912G>A; p.T304T; 18:202915-202915

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.631T>C; p.L211L; 18:197652-197652

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.604G>A; p.E202K; 18:197625-197625

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.604G>A; p.E202K; 18:197625-197625

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.797C>T; p.T266I; 18:199237-199237

 skin; trunkmalignant_melanomaSubstitution - Missense

c.561C>T; p.A187A; 18:196734-196734

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.817C>A; p.L273I; 18:199257-199257

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.613A>C; p.I205L; 18:197634-197634

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1373T>C; p.V458A; 18:211172-211172

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1238A>G; p.N413S; 18:210398-210398

 ovaryother; neoplasmSubstitution - Missense

c.1238A>G; p.N413S; 18:210398-210398

 ovaryother; neoplasmSubstitution - Missense

c.75T>A; p.P25P; 18:163366-163366

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.241G>T; p.E81*; 18:178978-178978

 breastcarcinomaSubstitution - Nonsense

c.738C>A; p.F246L; 18:198109-198109

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1021_1022GC>TG; p.A341C; 18:203176-203177

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1361A>C; p.K454T; 18:211160-211160

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.241G>A; p.E81K; 18:178978-178978

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.990_991insT; p.Y333fs*2; 18:203145-203146

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.990_991insT; p.Y333fs*2; 18:203145-203146

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.730G>A; p.D244N; 18:198101-198101

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.990_991insT; p.Y333fs*2; 18:203145-203146

 oesophagus; lower_thirdcarcinoma; adenocarcinomaInsertion - Frameshift

c.1218T>C; p.F406F; 18:210024-210024

 breastcarcinomaSubstitution - coding silent

c.1112G>T; p.R371L; 18:204640-204640

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1448G>A; p.R483H; 18:211247-211247

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.641A>T; p.K214I; 18:197662-197662

 ovaryother; neoplasmSubstitution - Missense

c.45T>G; p.F15L; 18:163336-163336

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense