Entrez Gene

Basic Information
Gene ID	8936
Name	WASF1
Synonymous	WAS protein family, member 1;WASF1;WAS protein family, member 1
Definition	WASP family protein member 1\|homology of dictyostelium scar 1\|protein WAVE-1\|verprolin homology domain-containing protein 1\|wiskott-Aldrich syndrome protein family member 1
Position	6q21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.198C>A; p.V66V; 6:110113396-110113396	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.974C>T; p.P325L; 6:110102136-110102136	skin	malignant_melanoma	Substitution - Missense
c.305G>A; p.R102Q; 6:110108645-110108645	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.714-1G>T; p.?; 6:110103558-110103558	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.676G>T; p.E226*; 6:110105444-110105444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1044T>G; p.P348P; 6:110102066-110102066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1287G>A; p.P429P; 6:110101823-110101823	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.533A>G; p.K178R; 6:110107084-110107084	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.250G>A; p.D84N; 6:110113344-110113344	breast	carcinoma	Substitution - Missense
c.1412C>T; p.P471L; 6:110101698-110101698	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1609C>T; p.R537C; 6:110100593-110100593	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1553G>A; p.R518H; 6:110100649-110100649	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1355C>T; p.P452L; 6:110101755-110101755	skin	malignant_melanoma	Substitution - Missense
c.766C>T; p.P256S; 6:110103505-110103505	breast	carcinoma	Substitution - Missense
c.730G>A; p.D244N; 6:110103541-110103541	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.797G>C; p.R266T; 6:110103474-110103474	breast	carcinoma	Substitution - Missense
c.189C>A; p.S63S; 6:110113405-110113405	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.375C>T; p.Y125Y; 6:110108575-110108575	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.756T>G; p.L252L; 6:110103515-110103515	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1605G>A; p.L535L; 6:110100597-110100597	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.160G>T; p.E54*; 6:110113434-110113434	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.409C>T; p.L137F; 6:110108541-110108541	skin	malignant_melanoma	Substitution - Missense
c.1289C>T; p.P430L; 6:110101821-110101821	skin	malignant_melanoma	Substitution - Missense
c.557G>A; p.R186H; 6:110105563-110105563	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.742G>C; p.G248R; 6:110103529-110103529	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.937A>G; p.T313A; 6:110102173-110102173	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1313G>A; p.R438Q; 6:110101797-110101797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.650A>G; p.D217G; 6:110105470-110105470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.52delC; p.L18fs*12; 6:110127550-110127550	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.430G>T; p.G144C; 6:110107187-110107187	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.692C>A; p.P231Q; 6:110105428-110105428	breast	carcinoma	Substitution - Missense
c.188C>T; p.S63F; 6:110113406-110113406	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.975A>C; p.P325P; 6:110102135-110102135	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.940G>A; p.G314S; 6:110102170-110102170	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.901A>G; p.T301A; 6:110102209-110102209	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1330_1331insA; p.T444fs*40; 6:110101779-110101780	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.337G>A; p.D113N; 6:110108613-110108613	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.984A>T; p.P328P; 6:110102126-110102126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.372G>A; p.T124T; 6:110108578-110108578	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.804G>A; p.E268E; 6:110103467-110103467	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1294C>T; p.L432L; 6:110101816-110101816	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.63C>T; p.G21G; 6:110127539-110127539	thyroid	other; neoplasm	Substitution - coding silent
c.415C>A; p.P139T; 6:110108535-110108535	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1384G>A; p.A462T; 6:110101726-110101726	breast	carcinoma	Substitution - Missense
c.247C>T; p.L83F; 6:110113347-110113347	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>C; p.V78L; 6:110113362-110113362	breast	carcinoma	Substitution - Missense
c.265G>T; p.E89*; 6:110113329-110113329	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.790C>G; p.L264V; 6:110103481-110103481	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.321A>T; p.Q107H; 6:110108629-110108629	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1316C>T; p.P439L; 6:110101794-110101794	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.635A>G; p.E212G; 6:110105485-110105485	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.371C>T; p.T124M; 6:110108579-110108579	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.787C>T; p.L263F; 6:110103484-110103484	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.89C>T; p.T30I; 6:110127513-110127513	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.777G>T; p.Q259H; 6:110103494-110103494	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.148G>T; p.D50Y; 6:110113446-110113446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>T; p.K176N; 6:110107089-110107089	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>T; p.T301I; 6:110102208-110102208	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.899C>T; p.A300V; 6:110102211-110102211	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1323A>T; p.S441S; 6:110101787-110101787	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1521A>C; p.K507N; 6:110101589-110101589	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1017A>T; p.S339S; 6:110102093-110102093	ovary	other; neoplasm	Substitution - coding silent
c.1017A>T; p.S339S; 6:110102093-110102093	ovary	other; neoplasm	Substitution - coding silent
c.1269G>A; p.L423L; 6:110101841-110101841	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1651G>T; p.E551*; 6:110100551-110100551	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.511G>A; p.D171N; 6:110107106-110107106	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1489G>A; p.A497T; 6:110101621-110101621	ovary	other; neoplasm	Substitution - Missense
c.320A>T; p.Q107L; 6:110108630-110108630	skin; leg	malignant_melanoma	Substitution - Missense
c.328C>T; p.Q110*; 6:110108622-110108622	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1503A>G; p.L501L; 6:110101607-110101607	breast	carcinoma	Substitution - coding silent
c.1071A>C; p.P357P; 6:110102039-110102039	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.575A>C; p.K192T; 6:110105545-110105545	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]