| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8772 |
Name | FADD |
Synonymous | Fas (TNFRSF6)-associated via death domain;FADD;Fas (TNFRSF6)-associated via death domain |
Definition | FAS-associated death domain protein|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor induced toxicity|mediator of receptor-induced toxicity |
Position | 11q13.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.474G>T; p.V158V; 11:70206320-70206320 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.172G>T; p.G58W; 11:70203631-70203631 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.101G>A; p.R34H; 11:70203560-70203560 |
stomach | adenocarcinoma | Substitution - Missense |
c.401C>T; p.P134L; 11:70206247-70206247 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.410T>A; p.L137Q; 11:70206256-70206256 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.55G>A; p.E19K; 11:70203514-70203514 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.466G>A; p.A156T; 11:70206312-70206312 |
liver | carcinoma | Substitution - Missense |
c.466G>A; p.A156T; 11:70206312-70206312 |
liver | carcinoma | Substitution - Missense |
c.377T>A; p.I126N; 11:70206223-70206223 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; follicular_lymphoma | Substitution - Missense |
c.342G>C; p.R114S; 11:70206188-70206188 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.331G>C; p.D111H; 11:70206177-70206177 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.331G>C; p.D111H; 11:70206177-70206177 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.289C>T; p.L97L; 11:70206135-70206135 |
pancreas | carcinoma | Substitution - coding silent |
c.375G>T; p.K125N; 11:70206221-70206221 |
pancreas | NS | Substitution - Missense |
c.621G>A; p.A207A; 11:70206467-70206467 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.427G>T; p.E143*; 11:70206273-70206273 |
haematopoietic_and_lymphoid_tissue; spleen | lymphoid_neoplasm; marginal_zone_lymphoma | Substitution - Nonsense |
c.48G>A; p.S16S; 11:70203507-70203507 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.186C>T; p.L62L; 11:70203645-70203645 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.581C>T; p.S194F; 11:70206427-70206427 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.378C>T; p.I126I; 11:70206224-70206224 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.449_450delAC; p.T151fs*24; 11:70206295-70206296 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.252delG; p.A86fs*52; 11:70203711-70203711 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.81C>A; p.C27*; 11:70203540-70203540 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |