Entrez Gene

Basic Information
Gene ID	84955
Name	NUDCD1
Synonymous	NudC domain containing 1;NUDCD1;NudC domain containing 1
Definition	chronic myelogenous leukemia tumor antigen 66\|nudC domain-containing protein 1\|tumor antigen CML66
Position	8q23
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1115A>C; p.D372A; 8:109275410-109275410	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1483_1484delGA; p.D495fs*17; 8:109243277-109243278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.557G>A; p.R186Q; 8:109293427-109293427	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.849T>C; p.T283T; 8:109281147-109281147	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.82G>C; p.E28Q; 8:109333929-109333929	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1527C>T; p.A509A; 8:109243234-109243234	skin	malignant_melanoma	Substitution - coding silent
c.1720C>A; p.L574I; 8:109243041-109243041	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1527C>T; p.A509A; 8:109243234-109243234	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.363C>T; p.F121F; 8:109296480-109296480	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.847A>G; p.T283A; 8:109281149-109281149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.847A>G; p.T283A; 8:109281149-109281149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.847A>G; p.T283A; 8:109281149-109281149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1491A>T; p.K497N; 8:109243270-109243270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.127G>C; p.E43Q; 8:109322455-109322455	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.265G>T; p.V89L; 8:109322317-109322317	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1696T>G; p.L566V; 8:109243065-109243065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.82G>A; p.E28K; 8:109333929-109333929	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.333T>C; p.C111C; 8:109296510-109296510	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1028+1delG; p.?; 8:109280967-109280967	liver	carcinoma	Unknown
c.1053_1055delGAA; p.K351delK; 8:109275470-109275472	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.624C>G; p.I208M; 8:109293360-109293360	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1440C>T; p.I480I; 8:109245341-109245341	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1663C>T; p.P555S; 8:109243098-109243098	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1663C>T; p.P555S; 8:109243098-109243098	skin	malignant_melanoma	Substitution - Missense
c.1494T>G; p.F498L; 8:109243267-109243267	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1390C>A; p.L464I; 8:109245391-109245391	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1708A>G; p.T570A; 8:109243053-109243053	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1708A>G; p.T570A; 8:109243053-109243053	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1065G>A; p.L355L; 8:109275460-109275460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1413C>T; p.S471S; 8:109245368-109245368	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.676C>T; p.L226F; 8:109289898-109289898	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1573C>T; p.P525S; 8:109243188-109243188	skin; trunk	malignant_melanoma	Substitution - Missense
c.1520A>T; p.Y507F; 8:109243241-109243241	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1378G>A; p.D460N; 8:109245403-109245403	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1441G>A; p.A481T; 8:109245340-109245340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.579_580insTTGGAT; p.D193_M194insLD; 8:109293404-109293405	lung	carcinoma; small_cell_carcinoma	Insertion - In frame
c.840G>C; p.W280C; 8:109281156-109281156	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1180A>C; p.N394H; 8:109271124-109271124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.825A>C; p.E275D; 8:109281171-109281171	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1382T>C; p.V461A; 8:109245399-109245399	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.805A>G; p.I269V; 8:109289769-109289769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.391G>A; p.D131N; 8:109296452-109296452	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1442C>T; p.A481V; 8:109245339-109245339	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.276C>G; p.D92E; 8:109296567-109296567	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.427G>T; p.E143*; 8:109296416-109296416	breast	carcinoma	Substitution - Nonsense
c.1687A>C; p.N563H; 8:109243074-109243074	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1687A>C; p.N563H; 8:109243074-109243074	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1518G>A; p.S506S; 8:109243243-109243243	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.589A>C; p.S197R; 8:109293395-109293395	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1741A>G; p.T581A; 8:109243020-109243020	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1460-6T>G; p.?; 8:109243307-109243307	liver	carcinoma	Unknown
c.1460-6T>G; p.?; 8:109243307-109243307	liver	carcinoma	Unknown
c.1028G>T; p.S343I; 8:109280968-109280968	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1071G>A; p.W357*; 8:109275454-109275454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.464T>C; p.M155T; 8:109293520-109293520	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.742T>A; p.S248T; 8:109289832-109289832	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1704T>C; p.V568V; 8:109243057-109243057	liver	carcinoma	Substitution - coding silent
c.1704T>C; p.V568V; 8:109243057-109243057	liver	carcinoma	Substitution - coding silent
c.1350A>T; p.K450N; 8:109245431-109245431	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1277A>G; p.N426S; 8:109271027-109271027	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1650A>G; p.L550L; 8:109243111-109243111	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1729delA; p.I577fs*1; 8:109243032-109243032	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1562G>A; p.R521H; 8:109243199-109243199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1562G>A; p.R521H; 8:109243199-109243199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1736T>A; p.V579E; 8:109243025-109243025	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.863C>G; p.T288R; 8:109281133-109281133	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.618C>A; p.V206V; 8:109293366-109293366	breast	carcinoma	Substitution - coding silent
c.1225G>A; p.E409K; 8:109271079-109271079	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1357C>T; p.P453S; 8:109245424-109245424	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1095A>G; p.K365K; 8:109275430-109275430	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.815A>C; p.K272T; 8:109289759-109289759	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1357C>T; p.P453S; 8:109245424-109245424	pancreas	carcinoma	Substitution - Missense
c.1351G>T; p.E451*; 8:109245430-109245430	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1202C>T; p.P401L; 8:109271102-109271102	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1705C>A; p.L569I; 8:109243056-109243056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.872T>C; p.I291T; 8:109281124-109281124	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1500C>A; p.A500A; 8:109243261-109243261	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1384G>T; p.D462Y; 8:109245397-109245397	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082T>G; p.V361G; 8:109275443-109275443	central_nervous_system; brain	glioma	Substitution - Missense
c.576G>T; p.L192F; 8:109293408-109293408	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1395C>G; p.L465L; 8:109245386-109245386	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1646G>A; p.S549N; 8:109243115-109243115	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.828T>G; p.P276P; 8:109281168-109281168	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.488C>A; p.P163H; 8:109293496-109293496	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.307C>T; p.R103*; 8:109296536-109296536	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.340C>T; p.R114C; 8:109296503-109296503	prostate	carcinoma	Substitution - Missense
c.847A>T; p.T283S; 8:109281149-109281149	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1165G>A; p.E389K; 8:109275360-109275360	skin	malignant_melanoma	Substitution - Missense
c.756A>C; p.L252F; 8:109289818-109289818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.453A>T; p.K151N; 8:109296390-109296390	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.870C>T; p.T290T; 8:109281126-109281126	breast	carcinoma	Substitution - coding silent
c.1664C>A; p.P555H; 8:109243097-109243097	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.143A>G; p.D48G; 8:109322439-109322439	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1554C>A; p.F518L; 8:109243207-109243207	breast	carcinoma	Substitution - Missense
c.1152G>C; p.M384I; 8:109275373-109275373	breast	carcinoma	Substitution - Missense
c.1496T>C; p.F499S; 8:109243265-109243265	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1099G>A; p.G367R; 8:109275426-109275426	liver	carcinoma	Substitution - Missense
c.1365C>T; p.F455F; 8:109245416-109245416	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.448G>T; p.E150*; 8:109296395-109296395	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.502C>T; p.H168Y; 8:109293482-109293482	skin	malignant_melanoma	Substitution - Missense
c.1615G>C; p.V539L; 8:109243146-109243146	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]