Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

84329

Name

HVCN1

Synonymous

hydrogen voltage gated channel 1;HVCN1;hydrogen voltage gated channel 1

Definition

hydrogen voltage-gated channel 1|voltage sensor domain-only protein|voltage-gated hydrogen channel 1

Position

12q24.11

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.418C>T; p.H140Y; 12:110651442-110651442

 skinmalignant_melanomaSubstitution - Missense

c.524C>T; p.A175V; 12:110651336-110651336

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.456G>A; p.M152I; 12:110651404-110651404

 skinmalignant_melanomaSubstitution - Missense

c.220G>A; p.V74I; 12:110661250-110661250

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.123C>T; p.N41N; 12:110661347-110661347

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.623G>A; p.R208Q; 12:110651237-110651237

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.570C>T; p.F190F; 12:110651290-110651290

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.570C>T; p.F190F; 12:110651290-110651290

 skinmalignant_melanomaSubstitution - coding silent

c.622C>T; p.R208W; 12:110651238-110651238

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.790C>T; p.R264*; 12:110649442-110649442

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.709C>A; p.Q237K; 12:110650215-110650215

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.633G>C; p.R211R; 12:110651227-110651227

 bone; femurchondrosarcomaSubstitution - coding silent

c.29C>T; p.T10I; 12:110661441-110661441

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.676C>T; p.R226W; 12:110650248-110650248

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.676C>T; p.R226W; 12:110650248-110650248

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.676C>T; p.R226W; 12:110650248-110650248

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.209C>T; p.A70V; 12:110661261-110661261

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.349C>T; p.L117F; 12:110655296-110655296

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.309C>T; p.V103V; 12:110655336-110655336

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.216T>A; p.P72P; 12:110661254-110661254

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.72C>A; p.F24L; 12:110661398-110661398

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.206C>T; p.A69V; 12:110661264-110661264

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.166C>G; p.Q56E; 12:110661304-110661304

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.196G>A; p.E66K; 12:110661274-110661274

 skinmalignant_melanomaSubstitution - Missense

c.166C>G; p.Q56E; 12:110661304-110661304

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.484C>T; p.R162C; 12:110651376-110651376

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.153G>A; p.E51E; 12:110661317-110661317

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.613C>A; p.R205R; 12:110651247-110651247

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.636C>A; p.I212I; 12:110651224-110651224

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.133T>C; p.W45R; 12:110661337-110661337

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - Missense

c.625G>T; p.V209L; 12:110651235-110651235

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.159G>A; p.E53E; 12:110661311-110661311

 skinmalignant_melanomaSubstitution - coding silent

c.305A>G; p.Q102R; 12:110661165-110661165

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.192C>T; p.G64G; 12:110661278-110661278

 prostatecarcinomaSubstitution - coding silent

c.192C>T; p.G64G; 12:110661278-110661278

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.119T>G; p.I40S; 12:110661351-110661351

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - Missense

c.714G>A; p.L238L; 12:110650210-110650210

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.528C>T; p.V176V; 12:110651332-110651332

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.95G>A; p.G32E; 12:110661375-110661375

 skin; upper_backmalignant_melanomaSubstitution - Missense

c.240C>T; p.P80P; 12:110661230-110661230

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.279G>A; p.R93R; 12:110661191-110661191

 skinmalignant_melanomaSubstitution - coding silent

c.177C>G; p.P59P; 12:110661293-110661293

 central_nervous_system; braingliomaSubstitution - coding silent

c.125A>G; p.Y42C; 12:110661345-110661345

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.219C>T; p.D73D; 12:110661251-110661251

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.511G>C; p.E171Q; 12:110651349-110651349

 NSNSSubstitution - Missense

c.529G>A; p.V177M; 12:110651331-110651331

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.471A>C; p.K157N; 12:110651389-110651389

 breastcarcinomaSubstitution - Missense

c.503A>G; p.H168R; 12:110651357-110651357

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.338C>T; p.A113V; 12:110655307-110655307

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.551T>A; p.L184H; 12:110651309-110651309

 breastcarcinomaSubstitution - Missense

c.134G>T; p.W45L; 12:110661336-110661336

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.717C>T; p.A239A; 12:110650207-110650207

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.509T>C; p.F170S; 12:110651351-110651351

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.613C>T; p.R205W; 12:110651247-110651247

 skinmalignant_melanomaSubstitution - Missense

c.595G>T; p.G199C; 12:110651265-110651265

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.601C>T; p.L201L; 12:110651259-110651259

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.299G>A; p.R100K; 12:110661171-110661171

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.552C>T; p.L184L; 12:110651308-110651308

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.552C>T; p.L184L; 12:110651308-110651308

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.667C>T; p.R223C; 12:110650257-110650257

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.191G>A; p.G64D; 12:110661279-110661279

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.60G>C; p.R20S; 12:110661410-110661410

 livercarcinomaSubstitution - Missense

c.189A>G; p.S63S; 12:110661281-110661281

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.607C>A; p.L203M; 12:110651253-110651253

 skinmalignant_melanomaSubstitution - Missense

c.114G>A; p.W38*; 12:110661356-110661356

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Nonsense

c.736G>C; p.E246Q; 12:110650188-110650188

 breastcarcinomaSubstitution - Missense