| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 84152 |
Name | PPP1R1B |
Synonymous | protein phosphatase 1, regulatory (inhibitor) subunit 1B;PPP1R1B;protein phosphatase 1, regulatory (inhibitor) subunit 1B |
Definition | dopamine and cAMP-regulated neuronal phosphoprotein 32|protein phosphatase 1 regulatory subunit 1B |
Position | 17q12 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.192C>T; p.L64L; 17:39629998-39629998 |
skin | malignant_melanoma | Substitution - coding silent |
c.197C>T; p.S66L; 17:39630003-39630003 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.563G>T; p.S188I; 17:39635724-39635724 |
kidney | other; neoplasm | Substitution - Missense |
c.587G>A; p.R196H; 17:39635837-39635837 |
thyroid | other; neoplasm | Substitution - Missense |
c.251G>A; p.R84H; 17:39633892-39633892 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.47C>T; p.P16L; 17:39627439-39627439 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.236T>C; p.L79P; 17:39630042-39630042 |
pancreas | carcinoma | Substitution - Missense |
c.496C>T; p.P166S; 17:39635657-39635657 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.67C>T; p.R23C; 17:39627459-39627459 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.97C>G; p.P33A; 17:39629185-39629185 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.33C>A; p.F11L; 17:39627425-39627425 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.152delC; p.S52fs*28; 17:39629549-39629549 |
liver | carcinoma; hepatocellular_carcinoma | Deletion - Frameshift |
c.493C>T; p.R165C; 17:39635654-39635654 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.493C>T; p.R165C; 17:39635654-39635654 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.573G>A; p.G191G; 17:39635823-39635823 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.388G>T; p.E130*; 17:39634029-39634029 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.18C>A; p.R6R; 17:39627410-39627410 |
liver | carcinoma | Substitution - coding silent |
c.18C>A; p.R6R; 17:39627410-39627410 |
liver | carcinoma | Substitution - coding silent |
c.198G>A; p.S66S; 17:39630004-39630004 |
skin | malignant_melanoma | Substitution - coding silent |
c.388G>C; p.E130Q; 17:39634029-39634029 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.491A>T; p.E164V; 17:39635652-39635652 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.185_186insCCTT; p.H63fs*26; 17:39629991-39629992 |
large_intestine; caecum | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.175_176GG>AA; p.G59K; 17:39629981-39629982 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.246G>A; p.V82V; 17:39633887-39633887 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.43G>C; p.A15P; 17:39627435-39627435 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.127G>A; p.E43K; 17:39629215-39629215 |
skin | malignant_melanoma | Substitution - Missense |
c.565+1G>A; p.?; 17:39635727-39635727 |
skin | malignant_melanoma | Unknown |
c.507G>A; p.L169L; 17:39635668-39635668 |
skin | malignant_melanoma | Substitution - coding silent |