| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 83998 |
Name | REG4 |
Synonymous | regenerating islet-derived family, member 4;REG4;regenerating islet-derived family, member 4 |
Definition | REG-4|REG-like protein|gastrointestinal secretory protein|reg IV|regenerating gene type IV|regenerating islet-derived protein 4|regenerating islet-derived protein IV |
Position | 1p13.1-p12 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.350C>T; p.S117F; 1:119798556-119798556 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.272C>T; p.P91L; 1:119799756-119799756 |
liver | carcinoma | Substitution - Missense |
c.101G>C; p.W34S; 1:119803132-119803132 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.223G>A; p.E75K; 1:119799805-119799805 |
skin | malignant_melanoma | Substitution - Missense |
c.20G>A; p.R7Q; 1:119808750-119808750 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.233C>T; p.T78I; 1:119799795-119799795 |
skin | malignant_melanoma | Substitution - Missense |
c.46G>T; p.A16S; 1:119808724-119808724 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.312G>A; p.Q104Q; 1:119798594-119798594 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.332C>A; p.A111D; 1:119798574-119798574 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.470G>A; p.R157Q; 1:119794625-119794625 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.194C>G; p.A65G; 1:119799834-119799834 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.470G>A; p.R157Q; 1:119794625-119794625 |
skin | malignant_melanoma | Substitution - Missense |
c.162C>T; p.A54A; 1:119803071-119803071 |
central_nervous_system; brain | atypical_teratoid-rhabdoid_tumour | Substitution - coding silent |
c.368T>C; p.M123T; 1:119798538-119798538 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.211C>T; p.L71L; 1:119799817-119799817 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.255C>A; p.G85G; 1:119799773-119799773 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.199C>G; p.L67V; 1:119799829-119799829 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.162C>A; p.A54A; 1:119803071-119803071 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.101G>T; p.W34L; 1:119803132-119803132 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.56G>A; p.G19E; 1:119808714-119808714 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.457C>A; p.L153M; 1:119794638-119794638 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.405T>C; p.N135N; 1:119798501-119798501 |
stomach | adenocarcinoma | Substitution - coding silent |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin | malignant_melanoma | Substitution - Missense |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin | malignant_melanoma | Substitution - Missense |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin | malignant_melanoma | Substitution - Missense |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin | malignant_melanoma | Substitution - Missense |
c.433G>A; p.E145K; 1:119794662-119794662 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.169G>T; p.E57*; 1:119799859-119799859 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin; trunk | malignant_melanoma | Substitution - Missense |
c.433G>A; p.E145K; 1:119794662-119794662 |
skin; trunk | malignant_melanoma | Substitution - Missense |
c.189C>T; p.N63N; 1:119799839-119799839 |
skin | malignant_melanoma | Substitution - coding silent |
c.35T>A; p.L12Q; 1:119808735-119808735 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.270G>A; p.Q90Q; 1:119799758-119799758 |
prostate | carcinoma; adenocarcinoma | Substitution - coding silent |
c.292G>C; p.D98H; 1:119799736-119799736 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.470G>C; p.R157P; 1:119794625-119794625 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.303G>C; p.K101N; 1:119799725-119799725 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.469C>T; p.R157*; 1:119794626-119794626 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.469C>T; p.R157*; 1:119794626-119794626 |
ovary | carcinoma; serous_carcinoma | Substitution - Nonsense |
c.168C>T; p.L56L; 1:119799860-119799860 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.365C>T; p.S122F; 1:119798541-119798541 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.405_406insT; p.N136fs*1; 1:119798500-119798501 |
endometrium | carcinoma; endometrioid_carcinoma | Insertion - Frameshift |
c.279G>A; p.W93*; 1:119799749-119799749 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; hairy_cell_leukaemia | Substitution - Nonsense |
c.279G>A; p.W93*; 1:119799749-119799749 |
skin; upper_leg | malignant_melanoma | Substitution - Nonsense |
c.210C>A; p.I70I; 1:119799818-119799818 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.409+2T>C; p.?; 1:119798495-119798495 |
stomach | carcinoma; adenocarcinoma | Unknown |
c.55G>T; p.G19*; 1:119808715-119808715 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Nonsense |