Entrez Gene

Basic Information
Gene ID	83706
Name	FERMT3
Synonymous	fermitin family member 3;FERMT3;fermitin family member 3
Definition	MIG2-like protein\|UNC-112 related protein 2\|fermitin family homolog 3\|kindlin 3\|unc-112-related protein 2
Position	11q13.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.431C>T; p.A144V; 11:64211088-64211088	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1068C>G; p.L356L; 11:64219778-64219778	skin	malignant_melanoma	Substitution - coding silent
c.271C>A; p.L91I; 11:64210721-64210721	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1624C>T; p.R542C; 11:64221082-64221082	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1739G>T; p.R580L; 11:64223104-64223104	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1698G>A; p.R566R; 11:64223063-64223063	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1698G>A; p.R566R; 11:64223063-64223063	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1698G>A; p.R566R; 11:64223063-64223063	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1698G>A; p.R566R; 11:64223063-64223063	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1567C>T; p.R523W; 11:64221025-64221025	central_nervous_system; brain	glioma	Substitution - Missense
c.36C>T; p.I12I; 11:64207400-64207400	breast	carcinoma	Substitution - coding silent
c.1078C>T; p.R360C; 11:64219788-64219788	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1186G>A; p.G396R; 11:64219985-64219985	skin	malignant_melanoma	Substitution - Missense
c.1461G>A; p.P487P; 11:64220573-64220573	breast	carcinoma	Substitution - coding silent
c.608C>T; p.P203L; 11:64211368-64211368	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1996G>T; p.A666S; 11:64223484-64223484	breast	carcinoma	Substitution - Missense
c.708C>T; p.L236L; 11:64211669-64211669	skin	malignant_melanoma	Substitution - coding silent
c.337C>T; p.R113C; 11:64210787-64210787	skin; neck	malignant_melanoma	Substitution - Missense
c.264C>T; p.D88D; 11:64210714-64210714	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1121G>A; p.R374H; 11:64219920-64219920	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.894G>T; p.Q298H; 11:64219358-64219358	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1038C>A; p.L346L; 11:64219748-64219748	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.363C>G; p.F121L; 11:64210813-64210813	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.714G>A; p.Q238Q; 11:64211675-64211675	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1135G>A; p.V379M; 11:64219934-64219934	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.265G>A; p.A89T; 11:64210715-64210715	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.340G>T; p.A114S; 11:64210790-64210790	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.550C>T; p.H184Y; 11:64211310-64211310	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1483G>C; p.D495H; 11:64220595-64220595	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1730G>A; p.R577Q; 11:64223095-64223095	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1522_1523insC; p.R510fs*105; 11:64220634-64220635	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1730G>A; p.R577Q; 11:64223095-64223095	urinary_tract; bladder	carcinoma	Substitution - Missense
c.331C>T; p.R111C; 11:64210781-64210781	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.331C>T; p.R111C; 11:64210781-64210781	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.994G>A; p.V332M; 11:64219623-64219623	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1519G>A; p.V507I; 11:64220631-64220631	breast	carcinoma	Substitution - Missense
c.1420C>A; p.L474M; 11:64220532-64220532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.129C>T; p.G43G; 11:64207493-64207493	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.758A>C; p.Y253S; 11:64211719-64211719	breast	carcinoma	Substitution - Missense
c.120G>A; p.S40S; 11:64207484-64207484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1468C>T; p.H490Y; 11:64220580-64220580	liver	carcinoma	Substitution - Missense
c.1468C>T; p.H490Y; 11:64220580-64220580	liver	carcinoma	Substitution - Missense
c.387C>T; p.R129R; 11:64210837-64210837	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1743C>T; p.I581I; 11:64223108-64223108	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1953G>A; p.E651E; 11:64223441-64223441	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1087C>T; p.R363*; 11:64219886-64219886	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.124A>G; p.I42V; 11:64207488-64207488	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1714G>T; p.G572C; 11:64223079-64223079	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1568G>A; p.R523Q; 11:64221026-64221026	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1329G>A; p.Q443Q; 11:64220441-64220441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.516C>T; p.G172G; 11:64211276-64211276	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.494G>T; p.S165I; 11:64211151-64211151	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1352G>A; p.G451D; 11:64220464-64220464	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1518C>T; p.L506L; 11:64220630-64220630	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.616G>A; p.D206N; 11:64211376-64211376	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1937G>A; p.R646Q; 11:64223425-64223425	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1653C>T; p.P551P; 11:64221111-64221111	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.15G>A; p.K5K; 11:64207379-64207379	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1762G>A; p.V588M; 11:64223127-64223127	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.949G>C; p.D317H; 11:64219578-64219578	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1010C>T; p.S337L; 11:64219639-64219639	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1285C>T; p.P429S; 11:64220288-64220288	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.660A>T; p.S220S; 11:64211420-64211420	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1931G>A; p.R644Q; 11:64223419-64223419	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1031A>T; p.D344V; 11:64219741-64219741	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.59T>G; p.V20G; 11:64207423-64207423	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.715C>G; p.Q239E; 11:64211676-64211676	breast	carcinoma	Substitution - Missense
c.1579G>T; p.A527S; 11:64221037-64221037	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.163C>T; p.R55C; 11:64210613-64210613	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.760T>G; p.Y254D; 11:64211721-64211721	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1723A>C; p.N575H; 11:64223088-64223088	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.793C>A; p.P265T; 11:64219257-64219257	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.183C>T; p.D61D; 11:64210633-64210633	skin	malignant_melanoma	Substitution - coding silent
c.735C>T; p.D245D; 11:64211696-64211696	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.361T>G; p.F121V; 11:64210811-64210811	skin	malignant_melanoma	Substitution - Missense
c.70G>C; p.E24Q; 11:64207434-64207434	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1886G>A; p.R629Q; 11:64223374-64223374	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1886G>A; p.R629Q; 11:64223374-64223374	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1583A>G; p.H528R; 11:64221041-64221041	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1032C>A; p.D344E; 11:64219742-64219742	liver	carcinoma	Substitution - Missense
c.771C>T; p.F257F; 11:64211732-64211732	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.771C>T; p.F257F; 11:64211732-64211732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.772G>T; p.D258Y; 11:64211733-64211733	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1855G>A; p.V619M; 11:64223343-64223343	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1855G>A; p.V619M; 11:64223343-64223343	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.879G>A; p.V293V; 11:64219343-64219343	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.557C>T; p.S186L; 11:64211317-64211317	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.26G>A; p.G9E; 11:64207390-64207390	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1920C>T; p.F640F; 11:64223408-64223408	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1937delG; p.A647fs*>21; 11:64223425-64223425	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1778G>A; p.R593H; 11:64223143-64223143	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1486G>T; p.A496S; 11:64220598-64220598	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.666G>C; p.K222N; 11:64211426-64211426	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1281C>T; p.P427P; 11:64220284-64220284	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1719C>T; p.I573I; 11:64223084-64223084	pancreas	carcinoma	Substitution - coding silent
c.1719C>T; p.I573I; 11:64223084-64223084	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1184C>A; p.P395H; 11:64219983-64219983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1176C>T; p.D392D; 11:64219975-64219975	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1176C>T; p.D392D; 11:64219975-64219975	liver	carcinoma	Substitution - coding silent
c.1272C>A; p.L424L; 11:64220275-64220275	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1972C>T; p.L658L; 11:64223460-64223460	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1367C>T; p.S456F; 11:64220479-64220479	central_nervous_system; brain	glioma	Substitution - Missense
c.1972C>T; p.L658L; 11:64223460-64223460	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.338G>A; p.R113H; 11:64210788-64210788	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1079G>A; p.R360H; 11:64219789-64219789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.436G>A; p.E146K; 11:64211093-64211093	urinary_tract; bladder	carcinoma	Substitution - Missense
c.536G>A; p.R179Q; 11:64211296-64211296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1738C>G; p.R580G; 11:64223103-64223103	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1189G>A; p.D397N; 11:64219988-64219988	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.528A>G; p.A176A; 11:64211288-64211288	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.886G>A; p.A296T; 11:64219350-64219350	breast	carcinoma	Substitution - Missense
c.1930C>A; p.R644R; 11:64223418-64223418	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1495G>A; p.E499K; 11:64220607-64220607	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.748C>T; p.R250C; 11:64211709-64211709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.738A>C; p.A246A; 11:64211699-64211699	pancreas	carcinoma	Substitution - coding silent
c.1621C>G; p.L541V; 11:64221079-64221079	prostate	carcinoma	Substitution - Missense
c.695C>T; p.S232L; 11:64211656-64211656	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1738C>T; p.R580C; 11:64223103-64223103	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]