Entrez Gene

Basic Information
Gene ID	83700
Name	JAM3
Synonymous	junctional adhesion molecule 3;JAM3;junctional adhesion molecule 3
Definition	junctional adhesion molecule C
Position	11q25
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.914C>T; p.T305M; 11:134148613-134148613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.446A>G; p.N149S; 11:134144295-134144295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>T; p.D269D; 11:134146005-134146005	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.349G>A; p.D117N; 11:134140728-134140728	urinary_tract; bladder	carcinoma	Substitution - Missense
c.576G>A; p.P192P; 11:134144823-134144823	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.591A>G; p.V197V; 11:134144838-134144838	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.99G>A; p.P33P; 11:134069047-134069047	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.475C>A; p.R159S; 11:134144324-134144324	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.92A>G; p.Y31C; 11:134069040-134069040	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1027_1029delGAG; p.E344delE; 11:134148813-134148815	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - In frame
c.773A>T; p.D258V; 11:134145971-134145971	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.433C>T; p.L145L; 11:134144282-134144282	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.103C>T; p.R35C; 11:134069051-134069051	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.726A>G; p.L242L; 11:134144973-134144973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.219G>C; p.L73L; 11:134139858-134139858	breast	carcinoma	Substitution - coding silent
c.518A>G; p.E173G; 11:134144367-134144367	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.134A>G; p.D45G; 11:134069082-134069082	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.432C>T; p.S144S; 11:134144281-134144281	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.116G>A; p.G39D; 11:134069064-134069064	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.706C>T; p.R236C; 11:134144953-134144953	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.392-2_392delAGG; p.?; 11:134144239-134144241	oesophagus	carcinoma; adenocarcinoma	Unknown
c.706C>T; p.R236C; 11:134144953-134144953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.706C>T; p.R236C; 11:134144953-134144953	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.275A>T; p.E92V; 11:134139914-134139914	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.681G>A; p.T227T; 11:134144928-134144928	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.151C>A; p.P51T; 11:134069099-134069099	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.487G>A; p.V163I; 11:134144336-134144336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1036G>A; p.D346N; 11:134149149-134149149	skin	malignant_melanoma	Substitution - Missense
c.1036G>A; p.D346N; 11:134149149-134149149	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.528C>T; p.I176I; 11:134144377-134144377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.900A>G; p.V300V; 11:134148599-134148599	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.528C>T; p.I176I; 11:134144377-134144377	breast	carcinoma	Substitution - coding silent
c.475C>T; p.R159C; 11:134144324-134144324	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.475C>T; p.R159C; 11:134144324-134144324	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.475C>T; p.R159C; 11:134144324-134144324	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.502C>T; p.R168C; 11:134144351-134144351	pancreas	carcinoma	Substitution - Missense
c.529G>A; p.E177K; 11:134144378-134144378	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.867A>G; p.G289G; 11:134148566-134148566	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.604A>C; p.T202P; 11:134144851-134144851	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.425A>G; p.K142R; 11:134144274-134144274	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.776C>T; p.S259F; 11:134145974-134145974	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.776C>T; p.S259F; 11:134145974-134145974	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.486C>T; p.V162V; 11:134144335-134144335	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.486C>T; p.V162V; 11:134144335-134144335	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.874delG; p.V294fs*10; 11:134148573-134148573	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.874delG; p.V294fs*10; 11:134148573-134148573	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.874delG; p.V294fs*10; 11:134148573-134148573	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.874delG; p.V294fs*10; 11:134148573-134148573	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.874delG; p.V294fs*10; 11:134148573-134148573	stomach	adenocarcinoma	Deletion - Frameshift
c.224G>A; p.G75E; 11:134139863-134139863	skin	malignant_melanoma	Substitution - Missense
c.659G>A; p.R220H; 11:134144906-134144906	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.493C>T; p.R165*; 11:134144342-134144342	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.302C>T; p.T101M; 11:134140681-134140681	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.302C>T; p.T101M; 11:134140681-134140681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.302C>T; p.T101M; 11:134140681-134140681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.124G>A; p.A42T; 11:134069072-134069072	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.679A>T; p.T227S; 11:134144926-134144926	skin	malignant_melanoma	Substitution - Missense
c.279T>C; p.S93S; 11:134140658-134140658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.866G>A; p.G289E; 11:134148565-134148565	skin	malignant_melanoma	Substitution - Missense
c.1026C>T; p.D342D; 11:134148812-134148812	central_nervous_system; brain	glioma	Substitution - coding silent
c.297C>T; p.I99I; 11:134140676-134140676	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.308C>T; p.S103L; 11:134140687-134140687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.308C>T; p.S103L; 11:134140687-134140687	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1065C>A; p.I355I; 11:134149178-134149178	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.211+6T>G; p.?; 11:134069165-134069165	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.546G>A; p.V182V; 11:134144793-134144793	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.455G>A; p.R152Q; 11:134144304-134144304	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.122C>T; p.S41L; 11:134069070-134069070	ovary	other; neoplasm	Substitution - Missense
c.202C>A; p.L68I; 11:134069150-134069150	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.873_874insG; p.V294fs*28; 11:134148572-134148573	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.873_874insG; p.V294fs*28; 11:134148572-134148573	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.873_874insG; p.V294fs*28; 11:134148572-134148573	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.707G>A; p.R236H; 11:134144954-134144954	pancreas	carcinoma	Substitution - Missense
c.707G>A; p.R236H; 11:134144954-134144954	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.707G>A; p.R236H; 11:134144954-134144954	breast	carcinoma	Substitution - Missense
c.309G>A; p.S103S; 11:134140688-134140688	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.263T>A; p.V88E; 11:134139902-134139902	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.263T>A; p.V88E; 11:134139902-134139902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.992G>A; p.G331E; 11:134148778-134148778	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.818C>T; p.A273V; 11:134146016-134146016	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.407G>A; p.R136H; 11:134144256-134144256	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]