| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 821 |
Name | CANX |
Synonymous | calnexin;CANX;calnexin |
Definition | major histocompatibility complex class I antigen-binding protein p88 |
Position | 5q35 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.1296C>T; p.D432D; 5:179722917-179722917 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1640A>T; p.K547I; 5:179724778-179724778 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.853G>A; p.E285K; 5:179716236-179716236 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.726G>C; p.L242F; 5:179716109-179716109 |
breast | carcinoma; HER-positive_carcinoma | Substitution - Missense |
c.589G>A; p.D197N; 5:179709933-179709933 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1234G>C; p.E412Q; 5:179722855-179722855 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1234G>C; p.E412Q; 5:179722855-179722855 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1524G>T; p.Q508H; 5:179724662-179724662 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1527C>A; p.T509T; 5:179724665-179724665 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - coding silent |
c.333G>T; p.E111D; 5:179708267-179708267 |
lung | carcinoma | Substitution - Missense |
c.1297_1298insT; p.D436fs*1; 5:179722918-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.333G>T; p.E111D; 5:179708267-179708267 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.1297_1298insT; p.D436fs*1; 5:179722918-179722919 |
liver | carcinoma | Insertion - Frameshift |
c.995C>G; p.P332R; 5:179719751-179719751 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.1752A>G; p.P584P; 5:179728617-179728617 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.1025+10T>G; p.?; 5:179719791-179719791 |
pancreas | carcinoma | Unknown |
c.1108C>T; p.Q370*; 5:179720486-179720486 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.1729G>T; p.D577Y; 5:179728594-179728594 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1443G>A; p.P481P; 5:179723704-179723704 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1561C>T; p.Q521*; 5:179724699-179724699 |
urinary_tract; bladder | carcinoma | Substitution - Nonsense |
c.63T>C; p.H21H; 5:179705744-179705744 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.657T>C; p.A219A; 5:179710001-179710001 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1613G>A; p.G538E; 5:179724751-179724751 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.21G>T; p.L7L; 5:179705702-179705702 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.666A>T; p.P222P; 5:179710010-179710010 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1497C>T; p.I499I; 5:179723758-179723758 |
skin | malignant_melanoma | Substitution - coding silent |
c.546G>T; p.K182N; 5:179709890-179709890 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1057C>A; p.P353T; 5:179720435-179720435 |
breast | carcinoma | Substitution - Missense |
c.17T>C; p.L6S; 5:179705698-179705698 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.37C>A; p.L13I; 5:179705718-179705718 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.1145A>T; p.K382I; 5:179720523-179720523 |
liver | carcinoma | Substitution - Missense |
c.1145A>T; p.K382I; 5:179720523-179720523 |
liver | carcinoma | Substitution - Missense |
c.1566G>A; p.P522P; 5:179724704-179724704 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.109G>A; p.D37N; 5:179705790-179705790 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
stomach | adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1298delT; p.F435fs*12; 5:179722919-179722919 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.820C>A; p.R274S; 5:179716203-179716203 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1076G>A; p.R359K; 5:179720454-179720454 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; hairy_cell_leukaemia | Substitution - Missense |
c.1081G>C; p.E361Q; 5:179720459-179720459 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1018G>A; p.E340K; 5:179719774-179719774 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.814C>T; p.P272S; 5:179716197-179716197 |
skin | malignant_melanoma | Substitution - Missense |
c.1723G>A; p.E575K; 5:179726757-179726757 |
pancreas | carcinoma | Substitution - Missense |
c.1406T>C; p.V469A; 5:179723667-179723667 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.1295A>G; p.D432G; 5:179722916-179722916 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.72T>C; p.H24H; 5:179705753-179705753 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.58G>A; p.A20T; 5:179705739-179705739 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.58G>A; p.A20T; 5:179705739-179705739 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.468T>C; p.N156N; 5:179708999-179708999 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.1366G>T; p.G456C; 5:179722987-179722987 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.784C>T; p.L262L; 5:179716167-179716167 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.1405G>A; p.V469I; 5:179723666-179723666 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.1005C>T; p.D335D; 5:179719761-179719761 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.490T>C; p.Y164H; 5:179709021-179709021 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.1033G>T; p.D345Y; 5:179720411-179720411 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1667C>T; p.A556V; 5:179726701-179726701 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.158C>A; p.P53H; 5:179705839-179705839 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.1196C>T; p.P399L; 5:179722817-179722817 |
breast | carcinoma | Substitution - Missense |
c.632C>T; p.T211M; 5:179709976-179709976 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1058C>T; p.P353L; 5:179720436-179720436 |
skin | malignant_melanoma | Substitution - Missense |
c.928G>C; p.A310P; 5:179719684-179719684 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.59C>T; p.A20V; 5:179705740-179705740 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.59C>T; p.A20V; 5:179705740-179705740 |
pancreas | carcinoma | Substitution - Missense |
c.821G>A; p.R274H; 5:179716204-179716204 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.1171C>A; p.P391T; 5:179720549-179720549 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.1330C>T; p.R444*; 5:179722951-179722951 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.1518+9delT; p.?; 5:179723788-179723788 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Unknown |
c.1235A>G; p.E412G; 5:179722856-179722856 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1425G>C; p.E475D; 5:179723686-179723686 |
prostate | carcinoma | Substitution - Missense |
c.1235A>G; p.E412G; 5:179722856-179722856 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1235A>G; p.E412G; 5:179722856-179722856 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.1196C>A; p.P399H; 5:179722817-179722817 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.274G>C; p.D92H; 5:179707160-179707160 |
breast | carcinoma | Substitution - Missense |
c.1565C>A; p.P522Q; 5:179724703-179724703 |
prostate | carcinoma | Substitution - Missense |
c.1452G>T; p.W484C; 5:179723713-179723713 |
thyroid | carcinoma | Substitution - Missense |
c.1544A>T; p.K515M; 5:179724682-179724682 |
pancreas | carcinoma | Substitution - Missense |