| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 80319 |
Name | CXXC4 |
Synonymous | CXXC finger protein 4;CXXC4;CXXC finger protein 4 |
Definition | CXXC finger 4|CXXC-type zinc finger protein 4|Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex)|inhibition of the Dvl and axin complex protein |
Position | 4q24 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.339G>T; p.Q113H; 4:104490957-104490957 |
lung | carcinoma; non_small_cell_carcinoma | Substitution - Missense |
c.570C>T; p.S190S; 4:104472349-104472349 |
breast | carcinoma | Substitution - coding silent |
c.570C>T; p.S190S; 4:104472349-104472349 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.556A>G; p.T186A; 4:104472363-104472363 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.168G>T; p.E56D; 4:104491128-104491128 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.7C>T; p.H3Y; 4:104491289-104491289 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.56C>G; p.P19R; 4:104491240-104491240 |
autonomic_ganglia | neuroblastoma | Substitution - Missense |
c.371G>A; p.G124E; 4:104490925-104490925 |
central_nervous_system; brain | glioma | Substitution - Missense |
c.148T>C; p.C50R; 4:104491148-104491148 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.193G>T; p.G65W; 4:104491103-104491103 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.249C>G; p.I83M; 4:104491047-104491047 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.587G>A; p.W196*; 4:104472332-104472332 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Nonsense |
c.382G>A; p.G128R; 4:104490914-104490914 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.382G>A; p.G128R; 4:104490914-104490914 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.112A>T; p.R38*; 4:104491184-104491184 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Nonsense |
c.4C>T; p.H2Y; 4:104491292-104491292 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.330C>T; p.D110D; 4:104490966-104490966 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.71C>T; p.A24V; 4:104491225-104491225 |
kidney | Wilms_tumour | Substitution - Missense |
c.107A>G; p.H36R; 4:104491189-104491189 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.432C>A; p.P144P; 4:104490864-104490864 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.59C>G; p.S20W; 4:104491237-104491237 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.298G>A; p.D100N; 4:104490998-104490998 |
upper_aerodigestive_tract; pharynx | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.358T>G; p.S120A; 4:104490938-104490938 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.278C>T; p.A93V; 4:104491018-104491018 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.450C>T; p.N150N; 4:104490846-104490846 |
breast | carcinoma | Substitution - coding silent |
c.249C>T; p.I83I; 4:104491047-104491047 |
skin | malignant_melanoma | Substitution - coding silent |
c.230C>T; p.S77L; 4:104491066-104491066 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.132C>T; p.C44C; 4:104491164-104491164 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.488G>T; p.G163V; 4:104490808-104490808 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.357_359delCTC; p.S123delS; 4:104490937-104490939 |
NS | malignant_melanoma | Deletion - In frame |
c.568A>T; p.S190C; 4:104472351-104472351 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.189C>G; p.R63R; 4:104491107-104491107 |
kidney | other; neoplasm | Substitution - coding silent |
c.189C>G; p.R63R; 4:104491107-104491107 |
pancreas | carcinoma | Substitution - coding silent |
c.63G>A; p.L21L; 4:104491233-104491233 |
thyroid | carcinoma | Substitution - coding silent |
c.577G>A; p.A193T; 4:104472342-104472342 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.479G>A; p.R160H; 4:104490817-104490817 |
skin | malignant_melanoma | Substitution - Missense |
c.479G>A; p.R160H; 4:104490817-104490817 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.183C>T; p.P61P; 4:104491113-104491113 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |