Entrez Gene

Basic Information
Gene ID	80315
Name	CPEB4
Synonymous	cytoplasmic polyadenylation element binding protein 4;CPEB4;cytoplasmic polyadenylation element binding protein 4
Definition	CPE-binding protein 4\|cytoplasmic polyadenylation element-binding protein 4
Position	5q21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.863A>G; p.Y288C; 5:173890596-173890596	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1181T>C; p.M394T; 5:173910578-173910578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.296G>A; p.S99N; 5:173890029-173890029	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.211C>G; p.Q71E; 5:173889944-173889944	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1526A>G; p.K509R; 5:173949577-173949577	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1414C>T; p.R472*; 5:173945098-173945098	ovary	other; neoplasm	Substitution - Nonsense
c.1414C>T; p.R472*; 5:173945098-173945098	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1809A>G; p.L603L; 5:173953119-173953119	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.1055G>A; p.S352N; 5:173890788-173890788	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1194T>G; p.N398K; 5:173910591-173910591	skin	malignant_melanoma	Substitution - Missense
c.1827C>T; p.Y609Y; 5:173953137-173953137	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.274G>T; p.E92*; 5:173890007-173890007	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.771T>C; p.H257H; 5:173890504-173890504	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2134C>T; p.P712S; 5:173956081-173956081	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2024G>A; p.C675Y; 5:173955971-173955971	liver	carcinoma	Substitution - Missense
c.788_789delAT; p.H263fs*6; 5:173890521-173890522	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1288T>C; p.S430P; 5:173944972-173944972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2159G>A; p.R720H; 5:173956106-173956106	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1111A>G; p.I371V; 5:173890844-173890844	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1591C>G; p.L531V; 5:173950004-173950004	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.962T>C; p.L321P; 5:173890695-173890695	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1329C>A; p.G443G; 5:173945013-173945013	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1449T>C; p.I483I; 5:173945133-173945133	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1273C>T; p.R425*; 5:173943040-173943040	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1050_1051delCC; p.P351fs*7; 5:173890783-173890784	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1775G>A; p.R592Q; 5:173951933-173951933	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.851C>T; p.P284L; 5:173890584-173890584	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1743T>C; p.T581T; 5:173951901-173951901	breast	carcinoma	Substitution - coding silent
c.1477C>T; p.R493C; 5:173949528-173949528	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1791G>A; p.A597A; 5:173953101-173953101	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.854G>T; p.W285L; 5:173890587-173890587	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.698A>G; p.H233R; 5:173890431-173890431	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1144G>A; p.D382N; 5:173910541-173910541	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1770A>G; p.P590P; 5:173951928-173951928	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1626C>A; p.L542L; 5:173950039-173950039	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1143_1144insCA; p.D382fs*13; 5:173910540-173910541	stomach	carcinoma; diffuse_adenocarcinoma	Insertion - Frameshift
c.1036C>T; p.Q346*; 5:173890769-173890769	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.1842C>T; p.T614T; 5:173953152-173953152	breast	carcinoma	Substitution - coding silent
c.189T>C; p.P63P; 5:173889922-173889922	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1410T>C; p.Y470Y; 5:173945094-173945094	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1735C>T; p.R579*; 5:173951893-173951893	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.414A>G; p.P138P; 5:173890147-173890147	liver	carcinoma	Substitution - coding silent
c.825G>A; p.A275A; 5:173890558-173890558	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1736G>A; p.R579Q; 5:173951894-173951894	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1736G>A; p.R579Q; 5:173951894-173951894	skin	malignant_melanoma	Substitution - Missense
c.1519G>T; p.E507*; 5:173949570-173949570	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1683G>T; p.W561C; 5:173951841-173951841	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.418T>G; p.L140V; 5:173890151-173890151	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1760T>C; p.V587A; 5:173951918-173951918	NS	NS	Substitution - Missense
c.499G>T; p.G167C; 5:173890232-173890232	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.626A>T; p.N209I; 5:173890359-173890359	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; angioimmunoblastic_T_cell_lymphoma	Substitution - Missense
c.43G>T; p.G15W; 5:173889776-173889776	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.372G>A; p.S124S; 5:173890105-173890105	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1960C>T; p.R654W; 5:173953270-173953270	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1334G>T; p.G445V; 5:173945018-173945018	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1420G>T; p.V474L; 5:173945104-173945104	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1826A>G; p.Y609C; 5:173953136-173953136	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.586C>A; p.P196T; 5:173890319-173890319	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.630C>A; p.F210L; 5:173890363-173890363	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1161G>A; p.E387E; 5:173910558-173910558	thyroid	carcinoma	Substitution - coding silent
c.1756G>T; p.G586C; 5:173951914-173951914	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.870T>C; p.S290S; 5:173890603-173890603	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.626A>G; p.N209S; 5:173890359-173890359	liver	carcinoma	Substitution - Missense
c.626A>G; p.N209S; 5:173890359-173890359	liver	carcinoma	Substitution - Missense
c.1490C>A; p.P497H; 5:173949541-173949541	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1369C>G; p.H457D; 5:173945053-173945053	oesophagus	carcinoma	Substitution - Missense
c.1765C>T; p.R589*; 5:173951923-173951923	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.867G>T; p.Q289H; 5:173890600-173890600	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.164G>A; p.S55N; 5:173889897-173889897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1648A>C; p.T550P; 5:173950061-173950061	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.406G>A; p.E136K; 5:173890139-173890139	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2111G>A; p.R704H; 5:173956058-173956058	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2T>C; p.M1T; 5:173889735-173889735	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1058C>T; p.S353F; 5:173890791-173890791	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1489C>T; p.P497S; 5:173949540-173949540	skin	malignant_melanoma	Substitution - Missense
c.996G>A; p.S332S; 5:173890729-173890729	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1252A>G; p.I418V; 5:173932494-173932494	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1005G>T; p.K335N; 5:173890738-173890738	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1398A>G; p.R466R; 5:173945082-173945082	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1268A>G; p.Y423C; 5:173943035-173943035	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.741G>T; p.Q247H; 5:173890474-173890474	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.704A>T; p.H235L; 5:173890437-173890437	central_nervous_system; brain	glioma	Substitution - Missense
c.1925G>A; p.R642H; 5:173953235-173953235	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1280G>A; p.R427K; 5:173943047-173943047	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.1049G>A; p.R350H; 5:173890782-173890782	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1049G>A; p.R350H; 5:173890782-173890782	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1345C>T; p.L449F; 5:173945029-173945029	skin	malignant_melanoma	Substitution - Missense
c.1595T>G; p.I532S; 5:173950008-173950008	ovary	other; neoplasm	Substitution - Missense
c.1269T>G; p.Y423*; 5:173943036-173943036	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.1595T>G; p.I532S; 5:173950008-173950008	ovary	other; neoplasm	Substitution - Missense
c.960G>A; p.G320G; 5:173890693-173890693	pancreas	carcinoma	Substitution - coding silent
c.874T>A; p.S292T; 5:173890607-173890607	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2156A>G; p.D719G; 5:173956103-173956103	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1845C>T; p.D615D; 5:173953155-173953155	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.710C>G; p.P237R; 5:173890443-173890443	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1017A>G; p.A339A; 5:173890750-173890750	breast	carcinoma	Substitution - coding silent
c.590C>T; p.A197V; 5:173890323-173890323	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.780C>A; p.P260P; 5:173890513-173890513	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1397G>T; p.R466I; 5:173945081-173945081	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1056C>G; p.S352R; 5:173890789-173890789	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1211G>A; p.R404H; 5:173932453-173932453	stomach	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]