Entrez Gene

Basic Information
Gene ID	7482
Name	WNT2B
Synonymous	wingless-type MMTV integration site family, member 2B;WNT2B;wingless-type MMTV integration site family, member 2B
Definition	XWNT2, Xenopus, homolog of\|protein Wnt-2b\|wingless-type MMTV integration site family, member 13
Position	1p13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.539G>A; p.R180H; 1:112516275-112516275	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.539G>A; p.R180H; 1:112516275-112516275	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.112C>T; p.R38C; 1:112509374-112509374	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.112C>T; p.R38C; 1:112509374-112509374	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.335G>A; p.R112H; 1:112515026-112515026	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.335G>A; p.R112H; 1:112515026-112515026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.335G>A; p.R112H; 1:112515026-112515026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.811G>A; p.G271R; 1:112517250-112517250	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.507C>T; p.D169D; 1:112516243-112516243	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.811G>A; p.G271R; 1:112517250-112517250	liver	carcinoma	Substitution - Missense
c.301C>T; p.R101*; 1:112514992-112514992	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.457G>A; p.A153T; 1:112516193-112516193	liver	carcinoma	Substitution - Missense
c.780C>T; p.R260R; 1:112517219-112517219	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.379G>A; p.V127I; 1:112515070-112515070	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.V127I; 1:112515070-112515070	breast	carcinoma	Substitution - Missense
c.724G>A; p.V242M; 1:112517163-112517163	ovary	other; neoplasm	Substitution - Missense
c.150G>C; p.L50L; 1:112509412-112509412	breast	carcinoma	Substitution - coding silent
c.800G>A; p.R267Q; 1:112517239-112517239	skin	malignant_melanoma	Substitution - Missense
c.242G>A; p.R81Q; 1:112514933-112514933	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.706G>A; p.E236K; 1:112517145-112517145	skin	malignant_melanoma	Substitution - Missense
c.749C>A; p.T250N; 1:112517188-112517188	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.515C>A; p.T172N; 1:112516251-112516251	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>T; p.L66L; 1:112514887-112514887	skin	malignant_melanoma	Substitution - coding silent
c.292G>A; p.E98K; 1:112514983-112514983	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.692G>A; p.R231Q; 1:112517131-112517131	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.641G>A; p.R214Q; 1:112516377-112516377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.531T>A; p.H177Q; 1:112516267-112516267	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.641G>A; p.R214Q; 1:112516377-112516377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.892G>A; p.D298N; 1:112517331-112517331	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.404-9T>C; p.?; 1:112516131-112516131	ovary	other; neoplasm	Unknown
c.802C>T; p.R268C; 1:112517241-112517241	skin	malignant_melanoma	Substitution - Missense
c.404-9T>C; p.?; 1:112516131-112516131	ovary	other; neoplasm	Unknown
c.802C>T; p.R268C; 1:112517241-112517241	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.668G>A; p.R223H; 1:112516404-112516404	breast	carcinoma	Substitution - Missense
c.803G>A; p.R268H; 1:112517242-112517242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.789T>C; p.D263D; 1:112517228-112517228	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.803G>A; p.R268H; 1:112517242-112517242	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.789T>C; p.D263D; 1:112517228-112517228	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1104G>T; p.K368N; 1:112520437-112520437	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.689G>A; p.R230Q; 1:112517128-112517128	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.986C>T; p.S329L; 1:112520319-112520319	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.713A>C; p.K238T; 1:112517152-112517152	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1125C>T; p.D375D; 1:112520458-112520458	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.590G>A; p.R197H; 1:112516326-112516326	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.304G>A; p.E102K; 1:112514995-112514995	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.814G>T; p.A272S; 1:112517253-112517253	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.322C>T; p.Q108*; 1:112515013-112515013	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.354T>C; p.C118C; 1:112515045-112515045	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.253_254delCT; p.L85fs*51; 1:112514944-112514945	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.205C>T; p.R69*; 1:112514896-112514896	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.731G>A; p.G244D; 1:112517170-112517170	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.956G>A; p.G319D; 1:112520289-112520289	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.93C>G; p.D31E; 1:112509355-112509355	pancreas	carcinoma	Substitution - Missense
c.509C>T; p.P170L; 1:112516245-112516245	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.313C>A; p.R105R; 1:112515004-112515004	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.396G>A; p.M132I; 1:112515087-112515087	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.323A>G; p.Q108R; 1:112515014-112515014	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.302G>A; p.R101Q; 1:112514993-112514993	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.302G>A; p.R101Q; 1:112514993-112514993	breast	carcinoma	Substitution - Missense
c.165C>T; p.R55R; 1:112509427-112509427	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.618G>A; p.K206K; 1:112516354-112516354	skin	malignant_melanoma	Substitution - coding silent
c.406A>G; p.S136G; 1:112516142-112516142	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.878G>A; p.R293H; 1:112517317-112517317	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1042C>T; p.R348*; 1:112520375-112520375	oesophagus	carcinoma	Substitution - Nonsense
c.1042C>T; p.R348*; 1:112520375-112520375	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.523C>T; p.R175*; 1:112516259-112516259	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.166G>A; p.V56I; 1:112509428-112509428	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.399C>T; p.L133L; 1:112515090-112515090	breast	carcinoma	Substitution - coding silent
c.815C>A; p.A272D; 1:112517254-112517254	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.874C>T; p.R292C; 1:112517313-112517313	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.386G>C; p.G129A; 1:112515077-112515077	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.583G>A; p.G195S; 1:112516319-112516319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.673G>T; p.G225C; 1:112516409-112516409	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.G195D; 1:112516320-112516320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.G195D; 1:112516320-112516320	skin	malignant_melanoma	Substitution - Missense
c.344G>A; p.R115H; 1:112515035-112515035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>T; p.A277V; 1:112517269-112517269	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.619G>A; p.E207K; 1:112516355-112516355	skin; abdomen	malignant_melanoma	Substitution - Missense
c.988A>C; p.K330Q; 1:112520321-112520321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.107C>T; p.S36L; 1:112509369-112509369	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.582C>T; p.Y194Y; 1:112516318-112516318	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.107C>T; p.S36L; 1:112509369-112509369	urinary_tract; bladder	carcinoma	Substitution - Missense
c.877C>T; p.R293C; 1:112517316-112517316	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.907G>C; p.D303H; 1:112517346-112517346	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.682-1G>C; p.?; 1:112517120-112517120	skin	malignant_melanoma	Unknown
c.453C>A; p.V151V; 1:112516189-112516189	breast	carcinoma	Substitution - coding silent
c.381C>T; p.V127V; 1:112515072-112515072	breast	carcinoma	Substitution - coding silent
c.1009A>G; p.I337V; 1:112520342-112520342	skin	malignant_melanoma	Substitution - Missense
c.757C>T; p.R253C; 1:112517196-112517196	breast	carcinoma	Substitution - Missense
c.282T>C; p.R94R; 1:112514973-112514973	liver	carcinoma	Substitution - coding silent
c.282T>C; p.R94R; 1:112514973-112514973	liver	carcinoma	Substitution - coding silent
c.606C>T; p.F202F; 1:112516342-112516342	urinary_tract; bladder	carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]