Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7453

Name

WARS

Synonymous

tryptophanyl-tRNA synthetase;WARS;tryptophanyl-tRNA synthetase

Definition

hWRS|interferon-induced protein 53|trpRS|tryptophan tRNA ligase 1, cytoplasmic|tryptophan--tRNA ligase, cytoplasmic

Position

14q32.31

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.142A>T; p.M48L; 14:100361879-100361879

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.610A>C; p.K204Q; 14:100353802-100353802

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.49G>A; p.A17T; 14:100369137-100369137

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.A17T; 14:100369137-100369137

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1221C>A; p.L407L; 14:100337095-100337095

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.316C>T; p.R106W; 14:100360660-100360660

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.158C>T; p.A53V; 14:100361863-100361863

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.161C>T; p.A54V; 14:100361860-100361860

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.903G>A; p.T301T; 14:100343311-100343311

 pancreascarcinomaSubstitution - coding silent

c.1093G>T; p.A365S; 14:100342418-100342418

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.1101G>T; p.Q367H; 14:100342410-100342410

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1101G>T; p.Q367H; 14:100342410-100342410

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.67G>A; p.V23I; 14:100369119-100369119

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.794G>A; p.G265D; 14:100346778-100346778

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1087G>A; p.D363N; 14:100342424-100342424

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.177G>A; p.K59K; 14:100361844-100361844

 livercarcinomaSubstitution - coding silent

c.177G>A; p.K59K; 14:100361844-100361844

 livercarcinomaSubstitution - coding silent

c.855T>C; p.A285A; 14:100343359-100343359

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.585G>A; p.M195I; 14:100353827-100353827

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.429G>A; p.M143I; 14:100354560-100354560

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.484C>T; p.R162W; 14:100354505-100354505

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1250G>T; p.R417M; 14:100337066-100337066

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.770A>T; p.H257L; 14:100346802-100346802

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.888C>A; p.I296I; 14:100343326-100343326

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.19G>T; p.A7S; 14:100369167-100369167

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.780C>T; p.F260F; 14:100346792-100346792

 skinmalignant_melanomaSubstitution - coding silent

c.775A>G; p.T259A; 14:100346797-100346797

 large_intestine; coloncarcinomaSubstitution - Missense

c.775A>G; p.T259A; 14:100346797-100346797

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1237_1254+30del48; p.?; 14:100337032-100337079

 ovarycarcinoma; serous_carcinomaUnknown

c.317G>A; p.R106Q; 14:100360659-100360659

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.859C>T; p.P287S; 14:100343355-100343355

 skinmalignant_melanomaSubstitution - Missense

c.485G>A; p.R162Q; 14:100354504-100354504

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.756G>A; p.V252V; 14:100346816-100346816

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.852G>T; p.Q284H; 14:100343362-100343362

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.539C>A; p.T180K; 14:100354450-100354450

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.519C>T; p.H173H; 14:100354470-100354470

 skinmalignant_melanomaSubstitution - coding silent

c.1365G>C; p.E455D; 14:100334926-100334926

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.408C>A; p.I136I; 14:100360568-100360568

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1311T>G; p.V437V; 14:100334980-100334980

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.850C>T; p.Q284*; 14:100343364-100343364

 skinmalignant_melanomaSubstitution - Nonsense

c.356G>T; p.R119L; 14:100360620-100360620

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.356G>T; p.R119L; 14:100360620-100360620

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.976A>G; p.R326G; 14:100342535-100342535

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1175G>T; p.G392V; 14:100337141-100337141

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.724G>A; p.G242R; 14:100353688-100353688

 skinmalignant_melanomaSubstitution - Missense

c.1173G>T; p.G391G; 14:100337143-100337143

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.897C>G; p.D299E; 14:100343317-100343317

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.580C>T; p.Q194*; 14:100353832-100353832

 skinmalignant_melanomaSubstitution - Nonsense

c.107T>G; p.I36S; 14:100361914-100361914

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.452A>C; p.E151A; 14:100354537-100354537

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1058G>T; p.S353I; 14:100342453-100342453

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.149A>G; p.Y50C; 14:100361872-100361872

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.523A>G; p.I175V; 14:100354466-100354466

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1357A>G; p.T453A; 14:100334934-100334934

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.215A>G; p.N72S; 14:100361806-100361806

 livercarcinomaSubstitution - Missense

c.215A>G; p.N72S; 14:100361806-100361806

 livercarcinomaSubstitution - Missense

c.446C>A; p.A149D; 14:100354543-100354543

 skin; subungualmalignant_melanoma; acral_lentiginousSubstitution - Missense

c.234A>G; p.T78T; 14:100361787-100361787

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.27G>A; p.L9L; 14:100369159-100369159

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1181G>A; p.C394Y; 14:100337135-100337135

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.982G>T; p.G328C; 14:100342529-100342529

 thyroidcarcinomaSubstitution - Missense

c.1354G>A; p.V452I; 14:100334937-100334937

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.217C>T; p.H73Y; 14:100361804-100361804

 skinmalignant_melanomaSubstitution - Missense

c.188C>A; p.P63H; 14:100361833-100361833

 skinmalignant_melanomaSubstitution - Missense

c.1207C>A; p.L403M; 14:100337109-100337109

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.966C>T; p.D322D; 14:100342545-100342545

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.915C>A; p.C305*; 14:100343299-100343299

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.1240G>A; p.E414K; 14:100337076-100337076

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.455_456insT; p.K153fs*1; 14:100354533-100354534

 breastcarcinoma; ductal_carcinomaInsertion - Frameshift

c.1391G>T; p.R464L; 14:100334900-100334900

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1282G>A; p.G428S; 14:100335009-100335009

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1282G>A; p.G428S; 14:100335009-100335009

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1127C>T; p.A376V; 14:100337189-100337189

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1222G>A; p.E408K; 14:100337094-100337094

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.355C>T; p.R119*; 14:100360621-100360621

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1359G>A; p.T453T; 14:100334932-100334932

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.92C>T; p.A31V; 14:100369094-100369094

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.92C>T; p.A31V; 14:100369094-100369094

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense