Entrez Gene

Basic Information
Gene ID	7379
Name	UPK2
Synonymous	uroplakin 2;UPK2;uroplakin 2
Definition	uroplakin II\|uroplakin-2
Position	11q23
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.235_236CC>TT; p.P79L; 11:118957234-118957235	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.93C>A; p.S31R; 11:118956899-118956899	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.535G>T; p.A179S; 11:118958213-118958213	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.418+1G>A; p.?; 11:118957669-118957669	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.149C>A; p.P50H; 11:118956955-118956955	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.462G>A; p.G154G; 11:118958140-118958140	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.237G>A; p.P79P; 11:118957236-118957236	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.394G>C; p.E132Q; 11:118957644-118957644	breast	carcinoma	Substitution - Missense
c.434_435CC>AT; p.S145Y; 11:118958112-118958113	skin; scalp	malignant_melanoma	Substitution - Missense
c.419-1G>C; p.?; 11:118958096-118958096	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.53C>A; p.A18D; 11:118956403-118956403	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.328G>T; p.V110L; 11:118957327-118957327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.70G>A; p.A24T; 11:118956420-118956420	skin	malignant_melanoma	Substitution - Missense
c.209-1G>A; p.?; 11:118957207-118957207	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Unknown
c.540_541GG>AA; p.G181S; 11:118958218-118958219	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.52G>A; p.A18T; 11:118956402-118956402	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.495C>T; p.V165V; 11:118958173-118958173	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.237delG; p.C80fs*8; 11:118957236-118957236	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.521T>G; p.F174C; 11:118958199-118958199	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.71C>A; p.A24D; 11:118956421-118956421	skin	malignant_melanoma	Substitution - Missense
c.174C>T; p.A58A; 11:118956980-118956980	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.71C>A; p.A24D; 11:118956421-118956421	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>G; p.L32L; 11:118956902-118956902	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.159C>T; p.L53L; 11:118956965-118956965	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.327C>T; p.L109L; 11:118957326-118957326	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.327C>T; p.L109L; 11:118957326-118957326	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.187C>T; p.R63W; 11:118956993-118956993	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.143T>C; p.L48S; 11:118956949-118956949	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.422G>A; p.R141K; 11:118958100-118958100	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.422G>A; p.R141K; 11:118958100-118958100	skin	malignant_melanoma	Substitution - Missense
c.239G>A; p.C80Y; 11:118957238-118957238	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.399C>T; p.I133I; 11:118957649-118957649	skin; arm	malignant_melanoma	Substitution - coding silent

COSMIC somatic mutation [Top]