Entrez Gene

Basic Information
Gene ID	7251
Name	TSG101
Synonymous	tumor susceptibility 101;TSG101;tumor susceptibility 101
Definition	ESCRT-I complex subunit TSG101\|tumor susceptibility gene 10\|tumor susceptibility gene 101\|tumor susceptibility gene 101 protein\|tumor susceptibility protein
Position	11p15
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.552T>C; p.G184G; 11:18502574-18502574	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.232G>T; p.D78Y; 11:18514803-18514803	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.44A>G; p.Y15C; 11:18519602-18519602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.790A>G; p.K264E; 11:18483923-18483923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.521A>G; p.Y174C; 11:18506884-18506884	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.889G>T; p.E297*; 11:18481824-18481824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.886G>T; p.E296*; 11:18481827-18481827	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.438T>A; p.I146I; 11:18509585-18509585	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.846C>T; p.A282A; 11:18481867-18481867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.960C>T; p.P320P; 11:18481753-18481753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.580G>A; p.G194S; 11:18502546-18502546	liver	carcinoma	Substitution - Missense
c.1039G>T; p.E347*; 11:18481674-18481674	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.508G>A; p.G170R; 11:18506897-18506897	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.42G>A; p.K14K; 11:18526775-18526775	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.754G>T; p.E252*; 11:18483959-18483959	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.1152C>A; p.A384A; 11:18480567-18480567	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069G>A; p.D357N; 11:18481644-18481644	breast	carcinoma	Substitution - Missense
c.992T>C; p.L331P; 11:18481721-18481721	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.1102C>T; p.R368C; 11:18480617-18480617	upper_aerodigestive_tract; sinonasal_and_nasal_cavity	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.469G>A; p.G157R; 11:18509554-18509554	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.67C>T; p.R23C; 11:18519579-18519579	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.555C>A; p.Y185*; 11:18502571-18502571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.555C>A; p.Y185*; 11:18502571-18502571	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.555C>A; p.Y185*; 11:18502571-18502571	breast	carcinoma	Substitution - Nonsense
c.555C>A; p.Y185*; 11:18502571-18502571	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.1008C>T; p.N336N; 11:18481705-18481705	central_nervous_system; brain	glioma	Substitution - coding silent
c.991C>T; p.L331L; 11:18481722-18481722	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.967C>T; p.P323S; 11:18481746-18481746	skin	malignant_melanoma	Substitution - Missense
c.794delA; p.K265fs*13; 11:18483919-18483919	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.794delA; p.K265fs*13; 11:18483919-18483919	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.440C>T; p.S147L; 11:18509583-18509583	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1057G>A; p.V353M; 11:18481656-18481656	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.800A>G; p.H267R; 11:18483913-18483913	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.644C>T; p.P215L; 11:18484069-18484069	skin	malignant_melanoma	Substitution - Missense
c.153A>G; p.E51E; 11:18516139-18516139	prostate	carcinoma	Substitution - coding silent
c.1068_1069GG>CT; p.D357Y; 11:18481644-18481645	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.43-2A>C; p.?; 11:18519605-18519605	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.391A>G; p.M131V; 11:18509632-18509632	breast	carcinoma	Substitution - Missense
c.1026C>A; p.I342I; 11:18481687-18481687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.750G>T; p.Q250H; 11:18483963-18483963	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.195T>C; p.G65G; 11:18514840-18514840	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1033T>C; p.L345L; 11:18481680-18481680	kidney	other; neoplasm	Substitution - coding silent
c.94T>A; p.Y32N; 11:18519552-18519552	skin; extremity	malignant_melanoma	Substitution - Missense
c.103C>G; p.L35V; 11:18519543-18519543	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.108A>C; p.K36N; 11:18519538-18519538	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.760A>C; p.N254H; 11:18483953-18483953	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.211C>T; p.P71S; 11:18514824-18514824	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1167C>T; p.L389L; 11:18480552-18480552	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.486C>A; p.S162S; 11:18506919-18506919	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.942C>T; p.I314I; 11:18481771-18481771	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.518C>T; p.P173L; 11:18506887-18506887	skin	malignant_melanoma	Substitution - Missense
c.565C>T; p.P189S; 11:18502561-18502561	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.826C>T; p.R276C; 11:18483887-18483887	prostate	carcinoma	Substitution - Missense
c.573A>C; p.P191P; 11:18502553-18502553	breast	carcinoma	Substitution - coding silent
c.860_861insA; p.N287fs*10; 11:18481852-18481853	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1153G>T; p.G385C; 11:18480566-18480566	bone; humerus	chondrosarcoma	Substitution - Missense
c.485C>T; p.S162F; 11:18506920-18506920	skin	malignant_melanoma	Substitution - Missense
c.492G>A; p.M164I; 11:18506913-18506913	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.729G>T; p.K243N; 11:18483984-18483984	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.729G>T; p.K243N; 11:18483984-18483984	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.729G>T; p.K243N; 11:18483984-18483984	large_intestine; colon	carcinoma	Substitution - Missense
c.729G>T; p.K243N; 11:18483984-18483984	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.431G>A; p.R144H; 11:18509592-18509592	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1017A>G; p.E339E; 11:18481696-18481696	breast	carcinoma	Substitution - coding silent
c.194-2A>C; p.?; 11:18514843-18514843	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.794A>G; p.K265R; 11:18483919-18483919	thyroid	carcinoma	Substitution - Missense
c.794A>G; p.K265R; 11:18483919-18483919	thyroid	carcinoma	Substitution - Missense
c.794A>G; p.K265R; 11:18483919-18483919	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.781G>A; p.E261K; 11:18483932-18483932	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.549-3delT; p.?; 11:18502580-18502580	ovary	carcinoma; serous_carcinoma	Unknown

COSMIC somatic mutation [Top]