Entrez Gene

Basic Information
Gene ID	7127
Name	TNFAIP2
Synonymous	tumor necrosis factor, alpha-induced protein 2;TNFAIP2;tumor necrosis factor, alpha-induced protein 2
Definition	TNF alpha-induced protein 2\|exocyst complex component 3-like 3\|primary response gene B94 protein\|tumor necrosis factor alpha-induced protein 2
Position	14q32
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.324G>T; p.A108A; 14:103127093-103127093	thyroid	other; neoplasm	Substitution - coding silent
c.1425A>C; p.P475P; 14:103132752-103132752	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.816C>T; p.R272R; 14:103127585-103127585	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1467G>A; p.V489V; 14:103132794-103132794	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1699C>A; p.H567N; 14:103133515-103133515	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1293C>T; p.S431S; 14:103131145-103131145	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1708C>T; p.P570S; 14:103133688-103133688	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.81_83delGAA; p.K31delK; 14:103126538-103126540	skin; extremity	malignant_melanoma	Deletion - In frame
c.81_83delGAA; p.K31delK; 14:103126538-103126540	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.1325T>G; p.V442G; 14:103131665-103131665	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1325T>G; p.V442G; 14:103131665-103131665	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1633C>A; p.Q545K; 14:103133449-103133449	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.1932C>T; p.S644S; 14:103135327-103135327	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1039G>T; p.V347L; 14:103130065-103130065	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1247C>A; p.T416K; 14:103131099-103131099	breast	carcinoma	Substitution - Missense
c.1177G>T; p.E393*; 14:103130393-103130393	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.227C>T; p.P76L; 14:103126684-103126684	NS	malignant_melanoma	Substitution - Missense
c.1699C>T; p.H567Y; 14:103133515-103133515	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.6G>T; p.S2S; 14:103126463-103126463	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.12C>A; p.A4A; 14:103126469-103126469	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1535G>A; p.C512Y; 14:103132862-103132862	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Substitution - Missense
c.1895G>A; p.S632N; 14:103135290-103135290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1868C>A; p.S623Y; 14:103135263-103135263	liver	carcinoma	Substitution - Missense
c.717C>G; p.F239L; 14:103127486-103127486	skin	malignant_melanoma	Substitution - Missense
c.1001G>A; p.R334Q; 14:103130027-103130027	skin	malignant_melanoma	Substitution - Missense
c.1609C>T; p.R537C; 14:103133425-103133425	central_nervous_system; brain	glioma	Substitution - Missense
c.1609C>T; p.R537C; 14:103133425-103133425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1578G>A; p.V526V; 14:103133394-103133394	skin	malignant_melanoma	Substitution - coding silent
c.1734C>T; p.L578L; 14:103133714-103133714	skin	malignant_melanoma	Substitution - coding silent
c.97A>G; p.K33E; 14:103126554-103126554	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.771C>T; p.F257F; 14:103127540-103127540	skin	malignant_melanoma	Substitution - coding silent
c.97A>G; p.K33E; 14:103126554-103126554	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1885C>T; p.R629C; 14:103135280-103135280	breast	carcinoma	Substitution - Missense
c.904A>G; p.M302V; 14:103129783-103129783	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1498G>T; p.D500Y; 14:103132825-103132825	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1498G>T; p.D500Y; 14:103132825-103132825	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.150_152delGAA; p.K54delK; 14:103126607-103126609	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Deletion - In frame
c.933G>A; p.R311R; 14:103129812-103129812	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.801C>T; p.F267F; 14:103127570-103127570	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1327C>T; p.P443S; 14:103131667-103131667	NS	malignant_melanoma	Substitution - Missense
c.1327C>T; p.P443S; 14:103131667-103131667	NS	malignant_melanoma	Substitution - Missense
c.180G>A; p.A60A; 14:103126637-103126637	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.218A>T; p.D73V; 14:103126675-103126675	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.136G>A; p.V46I; 14:103126593-103126593	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.748G>A; p.A250T; 14:103127517-103127517	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1434G>A; p.K478K; 14:103132761-103132761	breast	carcinoma	Substitution - coding silent
c.84G>T; p.K28N; 14:103126541-103126541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1631_1633delAGC; p.Q548delQ; 14:103133447-103133449	skin	malignant_melanoma	Deletion - In frame
c.1457C>T; p.A486V; 14:103132784-103132784	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1623G>A; p.K541K; 14:103133439-103133439	skin	malignant_melanoma	Substitution - coding silent
c.1840G>A; p.A614T; 14:103135235-103135235	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.844C>G; p.Q282E; 14:103127613-103127613	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.844C>G; p.Q282E; 14:103127613-103127613	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.844C>G; p.Q282E; 14:103127613-103127613	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.844C>G; p.Q282E; 14:103127613-103127613	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1707C>T; p.S569S; 14:103133687-103133687	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1919C>T; p.A640V; 14:103135314-103135314	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1292C>T; p.S431F; 14:103131144-103131144	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.901G>T; p.G301C; 14:103129780-103129780	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.921C>T; p.L307L; 14:103129800-103129800	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1549C>T; p.L517F; 14:103133365-103133365	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1905C>T; p.D635D; 14:103135300-103135300	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1775C>T; p.A592V; 14:103133755-103133755	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.975G>A; p.A325A; 14:103129854-103129854	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1756C>T; p.R586C; 14:103133736-103133736	stomach	adenocarcinoma	Substitution - Missense
c.83A>C; p.K28T; 14:103126540-103126540	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1891C>T; p.R631W; 14:103135286-103135286	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1136C>T; p.T379M; 14:103130352-103130352	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.204C>T; p.S68S; 14:103126661-103126661	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1856_1857insG; p.N621fs*6; 14:103135251-103135252	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1947C>T; p.S649S; 14:103135342-103135342	skin	malignant_melanoma	Substitution - coding silent
c.1228G>A; p.E410K; 14:103131080-103131080	skin	malignant_melanoma	Substitution - Missense
c.1608G>A; p.G536G; 14:103133424-103133424	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.119T>C; p.L40P; 14:103126576-103126576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1391C>T; p.T464I; 14:103131731-103131731	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1074C>T; p.S358S; 14:103130100-103130100	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.719C>A; p.P240H; 14:103127488-103127488	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1041G>T; p.V347V; 14:103130067-103130067	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.91A>G; p.K31E; 14:103126548-103126548	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1559C>A; p.A520D; 14:103133375-103133375	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.1559C>A; p.A520D; 14:103133375-103133375	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.1410T>C; p.H470H; 14:103131750-103131750	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.912C>G; p.L304L; 14:103129791-103129791	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.912C>G; p.L304L; 14:103129791-103129791	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1747G>T; p.E583*; 14:103133727-103133727	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1075G>A; p.E359K; 14:103130101-103130101	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1297C>T; p.R433W; 14:103131149-103131149	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1075G>A; p.E359K; 14:103130101-103130101	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]