Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7071

Name

KLF10

Synonymous

Kruppel-like factor 10;KLF10;Kruppel-like factor 10

Definition

Krueppel-like factor 10|TGFB-inducible early growth response protein 1|early growth response-alpha|transforming growth factor-beta-inducible early growth response protein 1|zinc finger transcription factor TIEG

Position

8q22.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.239G>T; p.G80V; 8:102652195-102652195

 livercarcinomaSubstitution - Missense

c.1004G>A; p.S335N; 8:102651328-102651328

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.284C>A; p.P95H; 8:102652048-102652048

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.383C>T; p.P128L; 8:102651949-102651949

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.271-2A>T; p.?; 8:102652063-102652063

 prostatecarcinoma; adenocarcinomaUnknown

c.385C>T; p.H129Y; 8:102651947-102651947

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.713C>T; p.T238M; 8:102651619-102651619

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.713C>T; p.T238M; 8:102651619-102651619

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1008G>A; p.P336P; 8:102651324-102651324

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1008G>A; p.P336P; 8:102651324-102651324

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.339G>A; p.A113A; 8:102651993-102651993

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.656A>C; p.D219A; 8:102651676-102651676

 livercarcinomaSubstitution - Missense

c.656A>C; p.D219A; 8:102651676-102651676

 livercarcinomaSubstitution - Missense

c.551C>A; p.S184Y; 8:102651781-102651781

 breastcarcinomaSubstitution - Missense

c.441C>T; p.L147L; 8:102651891-102651891

 skinmalignant_melanomaSubstitution - coding silent

c.551C>A; p.S184Y; 8:102651781-102651781

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1348C>T; p.R450C; 8:102650227-102650227

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1005C>T; p.S335S; 8:102651327-102651327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.338C>T; p.A113V; 8:102651994-102651994

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1124G>A; p.G375E; 8:102651208-102651208

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.39G>C; p.E13D; 8:102652395-102652395

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.99T>G; p.T33T; 8:102652335-102652335

 ovaryother; neoplasmSubstitution - coding silent

c.1190A>C; p.K397T; 8:102650385-102650385

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.18C>A; p.A6A; 8:102655584-102655584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.972C>T; p.P324P; 8:102651360-102651360

 skinmalignant_melanomaSubstitution - coding silent

c.958G>A; p.V320M; 8:102651374-102651374

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.808A>G; p.M270V; 8:102651524-102651524

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1176G>A; p.T392T; 8:102651156-102651156

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.337G>T; p.A113S; 8:102651995-102651995

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.484G>A; p.A162T; 8:102651848-102651848

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.178G>C; p.V60L; 8:102652256-102652256

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.992C>T; p.P331L; 8:102651340-102651340

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.123T>C; p.A41A; 8:102652311-102652311

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.994C>G; p.P332A; 8:102651338-102651338

 livercarcinomaSubstitution - Missense

c.744G>A; p.V248V; 8:102651588-102651588

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.994C>G; p.P332A; 8:102651338-102651338

 livercarcinomaSubstitution - Missense

c.45A>G; p.R15R; 8:102652389-102652389

 pancreascarcinomaSubstitution - coding silent

c.1027C>T; p.P343S; 8:102651305-102651305

 skinmalignant_melanomaSubstitution - Missense

c.775C>A; p.P259T; 8:102651557-102651557

 livercarcinomaSubstitution - Missense

c.775C>A; p.P259T; 8:102651557-102651557

 livercarcinomaSubstitution - Missense

c.775C>A; p.P259T; 8:102651557-102651557

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.469C>T; p.R157C; 8:102651863-102651863

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1055C>T; p.P352L; 8:102651277-102651277

 skinmalignant_melanomaSubstitution - Missense

c.373A>G; p.T125A; 8:102651959-102651959

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.35C>T; p.A12V; 8:102655567-102655567

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1343C>T; p.A448V; 8:102650232-102650232

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1343C>T; p.A448V; 8:102650232-102650232

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1076C>T; p.P359L; 8:102651256-102651256

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.240A>G; p.G80G; 8:102652194-102652194

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.22C>G; p.L8V; 8:102655580-102655580

 breastcarcinomaSubstitution - Missense

c.296C>T; p.S99F; 8:102652036-102652036

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.296C>T; p.S99F; 8:102652036-102652036

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.835C>T; p.L279F; 8:102651497-102651497

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.951C>T; p.V317V; 8:102651381-102651381

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.227A>T; p.N76I; 8:102652207-102652207

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1306C>T; p.R436W; 8:102650269-102650269

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1347G>A; p.R449R; 8:102650228-102650228

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.833C>T; p.P278L; 8:102651499-102651499

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1394G>T; p.S465I; 8:102650181-102650181

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.911delC; p.P304fs*31; 8:102651421-102651421

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.25C>T; p.Q9*; 8:102655577-102655577

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Nonsense

c.532C>A; p.L178I; 8:102651800-102651800

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.531C>A; p.I177I; 8:102651801-102651801

 breastcarcinomaSubstitution - coding silent

c.805C>T; p.P269S; 8:102651527-102651527

 prostatecarcinomaSubstitution - Missense

c.478G>T; p.A160S; 8:102651854-102651854

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1176G>C; p.T392T; 8:102651156-102651156

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.970C>G; p.P324A; 8:102651362-102651362

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.609C>T; p.A203A; 8:102651723-102651723

 prostatecarcinomaSubstitution - coding silent

c.1289C>T; p.A430V; 8:102650286-102650286

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1289C>T; p.A430V; 8:102650286-102650286

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1013G>A; p.G338D; 8:102651319-102651319

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.742G>A; p.V248M; 8:102651590-102651590

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.343T>G; p.S115A; 8:102651989-102651989

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.580G>A; p.E194K; 8:102651752-102651752

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1069G>A; p.V357I; 8:102651263-102651263

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1271C>T; p.T424M; 8:102650304-102650304

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.484G>T; p.A162S; 8:102651848-102651848

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.891G>A; p.Q297Q; 8:102651441-102651441

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.674G>T; p.S225I; 8:102651658-102651658

 livercarcinomaSubstitution - Missense

c.607G>A; p.A203T; 8:102651725-102651725

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.674G>T; p.S225I; 8:102651658-102651658

 livercarcinomaSubstitution - Missense

c.832C>T; p.P278S; 8:102651500-102651500

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.986C>T; p.S329L; 8:102651346-102651346

 skinmalignant_melanomaSubstitution - Missense

c.112G>A; p.D38N; 8:102652322-102652322

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1238C>T; p.S413F; 8:102650337-102650337

 skinmalignant_melanomaSubstitution - Missense

c.506C>G; p.T169S; 8:102651826-102651826

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.986C>A; p.S329*; 8:102651346-102651346

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.986C>A; p.S329*; 8:102651346-102651346

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense