Entrez Gene

Basic Information
Gene ID	7032
Name	TFF2
Synonymous	trefoil factor 2;TFF2;trefoil factor 2
Definition	spasmolysin\|spasmolytic polypeptide\|spasmolytic protein 1
Position	21q22.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.215_216CC>TT; p.P72L; 21:42349894-42349895	skin	malignant_melanoma	Substitution - Missense
c.257C>T; p.S86L; 21:42347605-42347605	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.110A>G; p.H37R; 21:42350000-42350000	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.295G>A; p.E99K; 21:42347567-42347567	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.127G>A; p.G43S; 21:42349983-42349983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.263G>A; p.R88Q; 21:42347599-42347599	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.263G>A; p.R88Q; 21:42347599-42347599	skin	malignant_melanoma	Substitution - Missense
c.263G>A; p.R88Q; 21:42347599-42347599	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.70G>A; p.E24K; 21:42350888-42350888	skin; neck	malignant_melanoma	Substitution - Missense
c.259G>A; p.D87N; 21:42347603-42347603	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.303C>T; p.C101C; 21:42347559-42347559	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.10C>T; p.R4*; 21:42350948-42350948	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.10C>T; p.R4*; 21:42350948-42350948	pancreas	NS	Substitution - Nonsense
c.243C>T; p.C81C; 21:42347619-42347619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.243C>T; p.C81C; 21:42347619-42347619	breast	carcinoma	Substitution - coding silent
c.16G>A; p.A6T; 21:42350942-42350942	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.235G>A; p.D79N; 21:42347627-42347627	skin	malignant_melanoma	Substitution - Missense
c.298G>A; p.E100K; 21:42347564-42347564	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.336C>G; p.I112M; 21:42347526-42347526	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.105C>T; p.S35S; 21:42350005-42350005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.320G>T; p.C107F; 21:42347542-42347542	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.266G>A; p.R89K; 21:42347596-42347596	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.96C>T; p.S32S; 21:42350014-42350014	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.80C>A; p.S27Y; 21:42350030-42350030	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.11G>T; p.R4L; 21:42350947-42350947	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.317G>A; p.C106Y; 21:42347545-42347545	liver	carcinoma	Substitution - Missense
c.194G>C; p.G65A; 21:42349916-42349916	ovary	other; neoplasm	Substitution - Missense
c.317G>A; p.C106Y; 21:42347545-42347545	liver	carcinoma	Substitution - Missense
c.194G>C; p.G65A; 21:42349916-42349916	ovary	other; neoplasm	Substitution - Missense
c.310C>T; p.R104W; 21:42347552-42347552	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.363G>A; p.P121P; 21:42347499-42347499	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.14A>G; p.D5G; 21:42350944-42350944	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.14A>G; p.D5G; 21:42350944-42350944	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]