Entrez Gene

Basic Information
Gene ID	6776
Name	STAT5A
Synonymous	signal transducer and activator of transcription 5A;STAT5A;signal transducer and activator of transcription 5A
Definition	-
Position	17q11.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1071C>T; p.G357G; 17:42301356-42301356	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.559G>T; p.A187S; 17:42299759-42299759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2377_2378delCT; p.S794fs?; 17:42310661-42310662	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1664G>A; p.W555*; 17:42306431-42306431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2018G>A; p.R673H; 17:42308289-42308289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2018G>A; p.R673H; 17:42308289-42308289	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.850G>A; p.E284K; 17:42300731-42300731	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2040C>T; p.S680S; 17:42308311-42308311	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1413C>T; p.H471H; 17:42305642-42305642	pancreas	carcinoma	Substitution - coding silent
c.1413C>T; p.H471H; 17:42305642-42305642	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1170C>T; p.N390N; 17:42304342-42304342	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.819C>T; p.D273D; 17:42300267-42300267	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.271G>A; p.A91T; 17:42290008-42290008	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.271G>A; p.A91T; 17:42290008-42290008	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1096delC; p.Q368fs*2; 17:42301381-42301381	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1038C>A; p.T346T; 17:42301323-42301323	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1015C>T; p.P339S; 17:42301300-42301300	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1096delC; p.Q368fs*2; 17:42301381-42301381	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1038C>A; p.T346T; 17:42301323-42301323	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.805G>C; p.E269Q; 17:42300253-42300253	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805G>C; p.E269Q; 17:42300253-42300253	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805G>C; p.E269Q; 17:42300253-42300253	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805G>C; p.E269Q; 17:42300253-42300253	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805G>C; p.E269Q; 17:42300253-42300253	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.799C>G; p.P267A; 17:42300247-42300247	thyroid	other; neoplasm	Substitution - Missense
c.320G>A; p.R107H; 17:42292006-42292006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.878T>C; p.I293T; 17:42300759-42300759	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.1054G>A; p.V352I; 17:42301339-42301339	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1099C>T; p.P367S; 17:42301384-42301384	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.834G>A; p.W278*; 17:42300715-42300715	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1694G>A; p.G565D; 17:42307415-42307415	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1492G>A; p.V498M; 17:42306259-42306259	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1363C>T; p.L455F; 17:42304635-42304635	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2305C>T; p.R769C; 17:42310589-42310589	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1907C>T; p.P636L; 17:42308178-42308178	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1091T>G; p.M364R; 17:42301376-42301376	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.118A>T; p.S40C; 17:42289529-42289529	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1151A>G; p.K384R; 17:42301436-42301436	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1906C>T; p.P636S; 17:42307723-42307723	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.98A>T; p.Y33F; 17:42289509-42289509	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1888G>A; p.A630T; 17:42307705-42307705	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1888G>A; p.A630T; 17:42307705-42307705	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1096C>T; p.P366S; 17:42301381-42301381	skin	malignant_melanoma	Substitution - Missense
c.152C>T; p.P51L; 17:42289889-42289889	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1946G>A; p.R649Q; 17:42308217-42308217	breast	carcinoma	Substitution - Missense
c.1568G>A; p.R523Q; 17:42306335-42306335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1393C>T; p.P465S; 17:42305622-42305622	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1882A>G; p.T628A; 17:42307699-42307699	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.346G>T; p.E116*; 17:42292032-42292032	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1314G>T; p.E438D; 17:42304586-42304586	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.795_796insG; p.P267fs*14; 17:42300243-42300244	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1887C>T; p.I629I; 17:42307704-42307704	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.2334C>T; p.R778R; 17:42310618-42310618	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1770T>A; p.N590K; 17:42307491-42307491	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1019A>G; p.Q340R; 17:42301304-42301304	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1902C>A; p.D634E; 17:42307719-42307719	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1657G>A; p.V553M; 17:42306424-42306424	breast	carcinoma	Substitution - Missense
c.1565A>G; p.N522S; 17:42306332-42306332	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1905C>T; p.S635S; 17:42307722-42307722	skin	malignant_melanoma	Substitution - coding silent
c.1905C>T; p.S635S; 17:42307722-42307722	skin	malignant_melanoma	Substitution - coding silent
c.1007A>G; p.K336R; 17:42301292-42301292	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1974C>G; p.D658E; 17:42308245-42308245	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.996C>T; p.F332F; 17:42301281-42301281	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1203C>T; p.C401C; 17:42304375-42304375	breast	carcinoma	Substitution - coding silent
c.1064T>C; p.L355P; 17:42301349-42301349	skin	malignant_melanoma	Substitution - Missense
c.1064T>C; p.L355P; 17:42301349-42301349	skin	malignant_melanoma	Substitution - Missense
c.2271C>T; p.T757T; 17:42310555-42310555	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1064T>C; p.L355P; 17:42301349-42301349	skin	malignant_melanoma	Substitution - Missense
c.1303G>A; p.V435M; 17:42304575-42304575	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2330C>A; p.S777Y; 17:42310614-42310614	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.82A>G; p.I28V; 17:42289493-42289493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.82A>G; p.I28V; 17:42289493-42289493	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1058G>A; p.R353H; 17:42301343-42301343	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.40G>T; p.A14S; 17:42289451-42289451	large_intestine	adenoma	Substitution - Missense
c.1490C>T; p.A497V; 17:42306257-42306257	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1072G>A; p.G358R; 17:42301357-42301357	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1551C>T; p.A517A; 17:42306318-42306318	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1513C>T; p.P505S; 17:42306280-42306280	breast	carcinoma	Substitution - Missense
c.1126G>T; p.E376*; 17:42301411-42301411	breast	carcinoma	Substitution - Nonsense
c.2034C>T; p.V678V; 17:42308305-42308305	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.405C>G; p.D135E; 17:42295648-42295648	skin	malignant_melanoma	Substitution - Missense
c.990-1G>A; p.?; 17:42301274-42301274	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1567C>T; p.R523W; 17:42306334-42306334	skin	malignant_melanoma	Substitution - Missense
c.1098C>T; p.P366P; 17:42301383-42301383	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1563C>T; p.S521S; 17:42306330-42306330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1681G>T; p.E561*; 17:42307402-42307402	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1285C>T; p.R429W; 17:42304557-42304557	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.489G>T; p.K163N; 17:42295732-42295732	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2384G>C; p.*795S; 17:42310668-42310668	lung	carcinoma; adenocarcinoma	Nonstop extension
c.562C>T; p.Q188*; 17:42299762-42299762	breast	carcinoma	Substitution - Nonsense
c.1536C>T; p.N512N; 17:42306303-42306303	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1651C>T; p.L551L; 17:42306418-42306418	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.534G>C; p.E178D; 17:42295777-42295777	breast	carcinoma	Substitution - Missense
c.2048A>C; p.Y683S; 17:42308319-42308319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2295G>T; p.E765D; 17:42310579-42310579	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.464C>T; p.T155M; 17:42295707-42295707	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1447C>T; p.L483L; 17:42305676-42305676	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]