| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6701 |
Name | SPRR2B |
Synonymous | small proline-rich protein 2B;SPRR2B;small proline-rich protein 2B |
Definition | SPR-2B |
Position | 1q21-q22 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.96C>A; p.C32*; 1:153070744-153070744 |
breast | carcinoma | Substitution - Nonsense |
c.144G>T; p.Q48H; 1:153070696-153070696 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.100G>A; p.E34K; 1:153070740-153070740 |
skin | malignant_melanoma | Substitution - Missense |
c.207G>A; p.P69P; 1:153070633-153070633 |
pituitary; craniopharyngeal_duct | craniopharyngioma; adamantinomatous | Substitution - coding silent |
c.198G>T; p.K66N; 1:153070642-153070642 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.198G>T; p.K66N; 1:153070642-153070642 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.105C>A; p.P35P; 1:153070735-153070735 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.203C>A; p.P68Q; 1:153070637-153070637 |
stomach | adenocarcinoma | Substitution - Missense |
c.131C>T; p.P44L; 1:153070709-153070709 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.190C>A; p.Q64K; 1:153070650-153070650 |
autonomic_ganglia | neuroblastoma | Substitution - Missense |
c.163C>T; p.P55S; 1:153070677-153070677 |
skin | malignant_melanoma | Substitution - Missense |
c.163C>T; p.P55S; 1:153070677-153070677 |
skin | malignant_melanoma | Substitution - Missense |
c.132C>T; p.P44P; 1:153070708-153070708 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.161A>G; p.Y54C; 1:153070679-153070679 |
stomach | adenocarcinoma | Substitution - Missense |
c.152A>T; p.Q51L; 1:153070688-153070688 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.40C>T; p.P14S; 1:153070800-153070800 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.181C>A; p.P61T; 1:153070659-153070659 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.142C>T; p.Q48*; 1:153070698-153070698 |
breast | carcinoma | Substitution - Nonsense |
c.188G>T; p.C63F; 1:153070652-153070652 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.116C>G; p.P39R; 1:153070724-153070724 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.100G>T; p.E34*; 1:153070740-153070740 |
breast | carcinoma | Substitution - Nonsense |
c.147G>A; p.Q49Q; 1:153070693-153070693 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.189C>T; p.C63C; 1:153070651-153070651 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |