Entrez Gene

Basic Information
Gene ID	6515
Name	SLC2A3
Synonymous	solute carrier family 2 (facilitated glucose transporter), member 3;SLC2A3;solute carrier family 2 (facilitated glucose transporter), member 3
Definition	GLUT-3\|glucose transporter type 3, brain\|solute carrier family 2, facilitated glucose transporter member 3
Position	12p13.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.398T>G; p.L133R; 12:7931357-7931357	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1361G>T; p.R454L; 12:7921543-7921543	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.951C>G; p.I317M; 12:7925859-7925859	urinary_tract; bladder	carcinoma	Substitution - Missense
c.147G>T; p.K49N; 12:7933109-7933109	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1248C>T; p.V416V; 12:7922845-7922845	lung	carcinoid-endocrine_tumour; atypical	Substitution - coding silent
c.956C>T; p.T319I; 12:7925854-7925854	breast	carcinoma	Substitution - Missense
c.1377G>T; p.E459D; 12:7921527-7921527	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1410C>T; p.H470H; 12:7921494-7921494	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.994A>G; p.R332G; 12:7924484-7924484	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.213C>T; p.S71S; 12:7933043-7933043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.451C>A; p.R151R; 12:7931304-7931304	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1267G>A; p.A423T; 12:7922826-7922826	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1267G>A; p.A423T; 12:7922826-7922826	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.213C>T; p.S71S; 12:7933043-7933043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.239C>T; p.S80F; 12:7933017-7933017	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1332T>C; p.A444A; 12:7921572-7921572	thyroid	other; neoplasm	Substitution - coding silent
c.24A>G; p.P8P; 12:7933894-7933894	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.860C>T; p.A287V; 12:7929685-7929685	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.799C>T; p.R267*; 12:7929746-7929746	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.1390G>T; p.A464S; 12:7921514-7921514	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.487G>A; p.V163I; 12:7931268-7931268	pancreas	carcinoma	Substitution - Missense
c.674-3C>A; p.?; 12:7929874-7929874	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.214G>A; p.V72I; 12:7933042-7933042	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.712G>A; p.D238N; 12:7929833-7929833	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1102G>A; p.G368R; 12:7922991-7922991	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.544G>A; p.E182K; 12:7930609-7930609	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.348G>A; p.S116S; 12:7931407-7931407	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.326G>T; p.G109V; 12:7931429-7931429	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1387C>T; p.R463W; 12:7921517-7921517	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.486C>T; p.I162I; 12:7931269-7931269	skin	malignant_melanoma	Substitution - coding silent
c.486C>T; p.I162I; 12:7931269-7931269	skin	malignant_melanoma	Substitution - coding silent
c.486C>T; p.I162I; 12:7931269-7931269	pancreas	carcinoma	Substitution - coding silent
c.683G>A; p.R228Q; 12:7929862-7929862	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.683G>A; p.R228Q; 12:7929862-7929862	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.65T>C; p.F22S; 12:7933853-7933853	skin	malignant_melanoma	Substitution - Missense
c.629G>A; p.R210K; 12:7930524-7930524	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.393C>T; p.C131C; 12:7931362-7931362	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	thyroid	other; neoplasm	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	liver	carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1445A>G; p.E482G; 12:7921459-7921459	thyroid	other; neoplasm	Substitution - Missense
c.539C>T; p.S180F; 12:7930614-7930614	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.22C>T; p.P8S; 12:7933896-7933896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.539C>T; p.S180F; 12:7930614-7930614	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.22C>T; p.P8S; 12:7933896-7933896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.911C>A; p.P304H; 12:7925899-7925899	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.225G>C; p.M75I; 12:7933031-7933031	oesophagus	carcinoma	Substitution - Missense
c.537G>A; p.G179G; 12:7930616-7930616	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.918T>G; p.Y306*; 12:7925892-7925892	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.733G>A; p.E245K; 12:7929812-7929812	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539C>A; p.S180Y; 12:7930614-7930614	urinary_tract; bladder	carcinoma	Substitution - Missense
c.404C>A; p.T135K; 12:7931351-7931351	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1327T>C; p.L443L; 12:7921577-7921577	breast	carcinoma	Substitution - coding silent
c.722A>G; p.E241G; 12:7929823-7929823	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1069-1G>T; p.?; 12:7923025-7923025	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.240C>T; p.S80S; 12:7933016-7933016	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.438G>A; p.S146S; 12:7931317-7931317	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.192C>T; p.S64S; 12:7933064-7933064	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1350C>T; p.V450V; 12:7921554-7921554	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.785G>T; p.R262I; 12:7929760-7929760	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1103G>T; p.G368V; 12:7922990-7922990	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.774A>G; p.L258L; 12:7929771-7929771	thyroid	other; neoplasm	Substitution - coding silent
c.1156T>G; p.W386G; 12:7922937-7922937	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1438delG; p.V480fs*4; 12:7921466-7921466	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.640A>C; p.I214L; 12:7930513-7930513	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.345G>A; p.K115K; 12:7931410-7931410	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1459G>A; p.E487K; 12:7921445-7921445	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1003C>A; p.H335N; 12:7924475-7924475	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1097G>C; p.C366S; 12:7922996-7922996	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.590T>C; p.L197P; 12:7930563-7930563	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.488T>C; p.V163A; 12:7931267-7931267	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.599C>T; p.A200V; 12:7930554-7930554	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.296T>A; p.L99Q; 12:7931459-7931459	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.928G>A; p.G310S; 12:7925882-7925882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1088G>T; p.S363I; 12:7923005-7923005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.395G>T; p.G132V; 12:7931360-7931360	urinary_tract; bladder	carcinoma	Substitution - Missense
c.395G>T; p.G132V; 12:7931360-7931360	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1021G>T; p.G341W; 12:7924457-7924457	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.637C>T; p.L213F; 12:7930516-7930516	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.149G>A; p.G50E; 12:7933107-7933107	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.86G>T; p.G29V; 12:7933832-7933832	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.646A>C; p.R216R; 12:7930507-7930507	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.327A>G; p.G109G; 12:7931428-7931428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.327A>G; p.G109G; 12:7931428-7931428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.327A>G; p.G109G; 12:7931428-7931428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.212C>T; p.S71F; 12:7933044-7933044	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1163T>C; p.I388T; 12:7922930-7922930	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.164C>T; p.S55F; 12:7933092-7933092	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.600A>G; p.A200A; 12:7930553-7930553	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.600A>G; p.A200A; 12:7930553-7930553	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.122T>G; p.F41C; 12:7933134-7933134	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1308C>T; p.T436T; 12:7921596-7921596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1348G>A; p.V450I; 12:7921556-7921556	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.589C>T; p.L197L; 12:7930564-7930564	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1235C>T; p.S412F; 12:7922858-7922858	skin	malignant_melanoma	Substitution - Missense
c.1315C>T; p.L439F; 12:7921589-7921589	skin	malignant_melanoma	Substitution - Missense
c.1000C>G; p.L334V; 12:7924478-7924478	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.931G>A; p.A311T; 12:7925879-7925879	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.259C>T; p.R87C; 12:7932997-7932997	pancreas	NS	Substitution - Missense
c.252C>T; p.F84F; 12:7933004-7933004	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.511-6T>C; p.?; 12:7930648-7930648	pancreas	carcinoma	Unknown
c.511-6T>C; p.?; 12:7930648-7930648	pancreas	carcinoma	Unknown
c.511-6T>C; p.?; 12:7930648-7930648	pancreas	carcinoma	Unknown
c.1107T>C; p.A369A; 12:7922986-7922986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.96T>A; p.N32K; 12:7933822-7933822	urinary_tract; bladder	carcinoma	Substitution - Missense
c.263T>C; p.F88S; 12:7932993-7932993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.241G>A; p.V81I; 12:7933015-7933015	liver	carcinoma	Substitution - Missense
c.241G>A; p.V81I; 12:7933015-7933015	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.607C>A; p.P203T; 12:7930546-7930546	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.608C>T; p.P203L; 12:7930545-7930545	skin	malignant_melanoma	Substitution - Missense
c.1170C>T; p.A390A; 12:7922923-7922923	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1415C>T; p.A472V; 12:7921489-7921489	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1069G>A; p.D357N; 12:7923024-7923024	liver	carcinoma	Substitution - Missense
c.1069G>A; p.D357N; 12:7923024-7923024	liver	carcinoma	Substitution - Missense
c.49G>A; p.A17T; 12:7933869-7933869	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1446G>A; p.E482E; 12:7921458-7921458	skin	malignant_melanoma	Substitution - coding silent
c.730G>A; p.D244N; 12:7929815-7929815	skin	malignant_melanoma	Substitution - Missense
c.482G>A; p.G161D; 12:7931273-7931273	central_nervous_system; brain	glioma	Substitution - Missense
c.1171G>A; p.E391K; 12:7922922-7922922	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1171G>A; p.E391K; 12:7922922-7922922	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.52A>G; p.T18A; 12:7933866-7933866	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.359T>C; p.L120P; 12:7931396-7931396	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.637C>G; p.L213V; 12:7930516-7930516	breast	carcinoma	Substitution - Missense
c.1166T>C; p.V389A; 12:7922927-7922927	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1067A>G; p.K356R; 12:7924411-7924411	breast	carcinoma	Substitution - Missense
c.881G>A; p.G294E; 12:7925929-7925929	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.678C>T; p.L226L; 12:7929867-7929867	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.733G>T; p.E245*; 12:7929812-7929812	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.22C>A; p.P8T; 12:7933896-7933896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.647G>T; p.R216I; 12:7930506-7930506	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.511-1G>T; p.?; 12:7930643-7930643	lung	carcinoma; small_cell_carcinoma	Unknown
c.647G>T; p.R216I; 12:7930506-7930506	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1088G>A; p.S363N; 12:7923005-7923005	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1242C>T; p.F414F; 12:7922851-7922851	skin	malignant_melanoma	Substitution - coding silent
c.1378G>A; p.D460N; 12:7921526-7921526	skin	malignant_melanoma	Substitution - Missense
c.235T>A; p.F79I; 12:7933021-7933021	skin	malignant_melanoma	Substitution - Missense
c.1150A>G; p.I384V; 12:7922943-7922943	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1181G>A; p.S394N; 12:7922912-7922912	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1250G>T; p.G417V; 12:7922843-7922843	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1267G>T; p.A423S; 12:7922826-7922826	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1309G>T; p.G437C; 12:7921595-7921595	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1193G>A; p.R398H; 12:7922900-7922900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1193G>A; p.R398H; 12:7922900-7922900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.905A>C; p.Q302P; 12:7925905-7925905	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1121T>C; p.V374A; 12:7922972-7922972	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.555G>A; p.P185P; 12:7930598-7930598	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1236C>A; p.S412S; 12:7922857-7922857	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.829C>A; p.Q277K; 12:7929716-7929716	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.976G>A; p.V326M; 12:7924502-7924502	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.555G>A; p.P185P; 12:7930598-7930598	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1273C>T; p.H425Y; 12:7921631-7921631	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.33A>C; p.I11I; 12:7933885-7933885	breast	carcinoma	Substitution - coding silent
c.1273C>T; p.H425Y; 12:7921631-7921631	urinary_tract; bladder	carcinoma	Substitution - Missense
c.892G>T; p.D298Y; 12:7925918-7925918	kidney	other; neoplasm	Substitution - Missense
c.709C>G; p.Q237E; 12:7929836-7929836	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1249G>A; p.G417R; 12:7922844-7922844	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1249G>A; p.G417R; 12:7922844-7922844	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1158G>A; p.W386*; 12:7922935-7922935	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1202C>T; p.A401V; 12:7922891-7922891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1087A>G; p.S363G; 12:7923006-7923006	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.660G>A; p.E220E; 12:7930493-7930493	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1087A>G; p.S363G; 12:7923006-7923006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.25G>T; p.A9S; 12:7933893-7933893	liver	carcinoma	Substitution - Missense
c.25G>T; p.A9S; 12:7933893-7933893	liver	carcinoma	Substitution - Missense
c.164C>G; p.S55C; 12:7933092-7933092	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.318C>A; p.C106*; 12:7931437-7931437	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.271C>T; p.R91C; 12:7931484-7931484	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]