| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6502 |
Name | SKP2 |
Synonymous | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase;SKP2;S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
Definition | CDK2/cyclin A-associated protein p45|F-box/LRR-repeat protein 1|S-phase kinase-associated protein 2|S-phase kinase-associated protein 2 (p45)|p45skp2 |
Position | 5p13 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.213G>A; p.K71K; 5:36152975-36152975 |
breast | carcinoma; HER-positive_carcinoma | Substitution - coding silent |
c.902-1G>C; p.?; 5:36176964-36176964 |
ovary | carcinoma; serous_carcinoma | Unknown |
c.503C>T; p.S168L; 5:36166629-36166629 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.404C>T; p.S135F; 5:36166530-36166530 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |