Entrez Gene

Basic Information
Gene ID	64078
Name	SLC28A3
Synonymous	solute carrier family 28 (concentrative nucleoside transporter), member 3;SLC28A3;solute carrier family 28 (concentrative nucleoside transporter), member 3
Definition	concentrative Na(+)-nucleoside cotransporter 3\|concentrative Na+-nucleoside cotransporter\|solute carrier family 28 (sodium-coupled nucleoside transporter), member 3\|solute carrier family 28 member 3
Position	9q22.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.185A>G; p.D62G; 9:84309686-84309686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.185A>G; p.D62G; 9:84309686-84309686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.185A>G; p.D62G; 9:84309686-84309686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1651C>T; p.R551C; 9:84280879-84280879	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1651C>T; p.R551C; 9:84280879-84280879	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.607T>A; p.S203T; 9:84299643-84299643	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2036C>T; p.P679L; 9:84278258-84278258	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2036C>T; p.P679L; 9:84278258-84278258	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.301C>A; p.L101I; 9:84305287-84305287	breast	carcinoma	Substitution - Missense
c.903G>A; p.M301I; 9:84294234-84294234	breast	carcinoma	Substitution - Missense
c.1988G>A; p.G663E; 9:84278306-84278306	skin	malignant_melanoma	Substitution - Missense
c.1469T>A; p.F490Y; 9:84285523-84285523	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.589G>A; p.G197S; 9:84299661-84299661	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.191C>T; p.P64L; 9:84309680-84309680	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1538A>T; p.Y513F; 9:84285454-84285454	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100G>C; p.G367A; 9:84290203-84290203	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1825G>A; p.A609T; 9:84279978-84279978	pancreas	carcinoma	Substitution - Missense
c.2015G>A; p.G672D; 9:84278279-84278279	liver	carcinoma	Substitution - Missense
c.2015G>A; p.G672D; 9:84278279-84278279	liver	carcinoma	Substitution - Missense
c.1950-2A>T; p.?; 9:84278346-84278346	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Unknown
c.1737G>A; p.M579I; 9:84280066-84280066	skin	malignant_melanoma	Substitution - Missense
c.682C>T; p.P228S; 9:84298007-84298007	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1792G>A; p.G598R; 9:84280011-84280011	skin	malignant_melanoma	Substitution - Missense
c.792G>A; p.L264L; 9:84297290-84297290	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.944T>A; p.V315D; 9:84292747-84292747	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.304C>T; p.R102W; 9:84305284-84305284	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.534G>A; p.W178*; 9:84299716-84299716	skin; shoulder	malignant_melanoma	Substitution - Nonsense
c.824T>A; p.F275Y; 9:84297258-84297258	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1790C>T; p.A597V; 9:84280013-84280013	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.376C>T; p.H126Y; 9:84302348-84302348	urinary_tract; bladder	carcinoma	Substitution - Missense
c.453C>A; p.Y151*; 9:84302271-84302271	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.58C>T; p.Q20*; 9:84340576-84340576	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1867C>T; p.H623Y; 9:84279347-84279347	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.182A>G; p.Q61R; 9:84309689-84309689	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.460C>A; p.R154R; 9:84302264-84302264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.61-1G>A; p.?; 9:84313455-84313455	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Unknown
c.61-1G>A; p.?; 9:84313455-84313455	urinary_tract; bladder	carcinoma	Unknown
c.783G>T; p.Q261H; 9:84297906-84297906	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.84C>T; p.N28N; 9:84313431-84313431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.84C>T; p.N28N; 9:84313431-84313431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.84C>T; p.N28N; 9:84313431-84313431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1083C>T; p.H361H; 9:84290220-84290220	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1734C>T; p.S578S; 9:84280069-84280069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1254C>A; p.L418L; 9:84288074-84288074	breast	carcinoma	Substitution - coding silent
c.1118G>A; p.G373E; 9:84290185-84290185	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1729A>G; p.T577A; 9:84280801-84280801	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1084G>A; p.A362T; 9:84290219-84290219	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1534G>T; p.G512C; 9:84285458-84285458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.692G>T; p.W231L; 9:84297997-84297997	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1385C>A; p.S462Y; 9:84286007-84286007	urinary_tract; bladder	carcinoma	Substitution - Missense
c.104A>T; p.N35I; 9:84313411-84313411	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.37G>A; p.G13S; 9:84340597-84340597	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1458C>A; p.C486*; 9:84285534-84285534	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1227T>C; p.P409P; 9:84288101-84288101	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1350C>T; p.I450I; 9:84286042-84286042	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1598G>T; p.R533M; 9:84285394-84285394	pancreas	carcinoma	Substitution - Missense
c.103A>C; p.N35H; 9:84313412-84313412	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.783+1G>T; p.?; 9:84297905-84297905	lung	carcinoma; small_cell_carcinoma	Unknown
c.1459T>G; p.S487A; 9:84285533-84285533	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1906A>G; p.N636D; 9:84279308-84279308	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.968C>G; p.T323R; 9:84292723-84292723	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.122C>T; p.A41V; 9:84313393-84313393	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1992C>T; p.N664N; 9:84278302-84278302	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.783+6T>C; p.?; 9:84297900-84297900	stomach	carcinoma; adenocarcinoma	Unknown
c.1401C>G; p.A467A; 9:84285991-84285991	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.942+2T>C; p.?; 9:84294193-84294193	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2056G>T; p.G686W; 9:84278238-84278238	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1173A>G; p.T391T; 9:84288155-84288155	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1723G>A; p.G575R; 9:84280807-84280807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.204A>G; p.E68E; 9:84309667-84309667	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.715C>T; p.L239F; 9:84297974-84297974	skin	malignant_melanoma	Substitution - Missense
c.659A>T; p.Y220F; 9:84299591-84299591	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.944T>C; p.V315A; 9:84292747-84292747	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.285G>A; p.R95R; 9:84305303-84305303	skin	malignant_melanoma	Substitution - coding silent
c.266C>T; p.T89I; 9:84305322-84305322	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.755C>T; p.A252V; 9:84297934-84297934	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1975G>A; p.V659I; 9:84278319-84278319	liver	carcinoma	Substitution - Missense
c.460C>T; p.R154*; 9:84302264-84302264	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.460C>T; p.R154*; 9:84302264-84302264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.460C>T; p.R154*; 9:84302264-84302264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.860A>G; p.K287R; 9:84297222-84297222	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1975G>A; p.V659I; 9:84278319-84278319	liver	carcinoma	Substitution - Missense
c.1204G>T; p.A402S; 9:84288124-84288124	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.460C>T; p.R154*; 9:84302264-84302264	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1829G>T; p.G610V; 9:84279385-84279385	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.1099G>T; p.G367W; 9:84290204-84290204	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.254G>A; p.R85K; 9:84305334-84305334	skin	malignant_melanoma	Substitution - Missense
c.1045C>T; p.R349*; 9:84290258-84290258	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.60+8G>T; p.?; 9:84340566-84340566	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.612C>T; p.F204F; 9:84299638-84299638	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1564G>T; p.A522S; 9:84285428-84285428	liver	carcinoma	Substitution - Missense
c.1564G>T; p.A522S; 9:84285428-84285428	liver	carcinoma	Substitution - Missense
c.1175C>T; p.A392V; 9:84288153-84288153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1175C>T; p.A392V; 9:84288153-84288153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1464C>T; p.Y488Y; 9:84285528-84285528	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1556A>C; p.E519A; 9:84285436-84285436	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1753C>T; p.R585C; 9:84280050-84280050	pancreas	NS	Substitution - Missense
c.1753C>T; p.R585C; 9:84280050-84280050	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.613G>A; p.G205S; 9:84299637-84299637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1753C>T; p.R585C; 9:84280050-84280050	pancreas	carcinoma	Substitution - Missense
c.338A>G; p.Y113C; 9:84302386-84302386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1234G>T; p.E412*; 9:84288094-84288094	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Nonsense
c.335-6G>A; p.?; 9:84302395-84302395	stomach	adenocarcinoma	Unknown
c.1234G>C; p.E412Q; 9:84288094-84288094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1754G>C; p.R585P; 9:84280049-84280049	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.243-1G>T; p.?; 9:84305346-84305346	lung	carcinoma; adenocarcinoma	Unknown
c.1898T>G; p.F633C; 9:84279316-84279316	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1272G>T; p.M424I; 9:84288056-84288056	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.62A>T; p.N21I; 9:84313453-84313453	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.116G>A; p.S39N; 9:84313399-84313399	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1759A>G; p.I587V; 9:84280044-84280044	breast	carcinoma	Substitution - Missense
c.497T>C; p.L166P; 9:84302227-84302227	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.497T>C; p.L166P; 9:84302227-84302227	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1494A>G; p.G498G; 9:84285498-84285498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1142C>A; p.S381Y; 9:84290161-84290161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.72C>A; p.N24K; 9:84313443-84313443	skin	malignant_melanoma	Substitution - Missense
c.356C>T; p.S119L; 9:84302368-84302368	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.335-10T>A; p.?; 9:84302399-84302399	ovary	other; neoplasm	Unknown
c.1962G>A; p.K654K; 9:84278332-84278332	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.534_536delGAG; p.W178_S179>C; 9:84299714-84299716	endometrium	carcinoma; endometrioid_carcinoma	Complex - deletion inframe
c.293A>T; p.K98I; 9:84305295-84305295	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1559T>G; p.F520C; 9:84285433-84285433	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.199A>C; p.R67R; 9:84309672-84309672	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3G>T; p.M1I; 9:84340631-84340631	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.240delA; p.C82fs*29; 9:84309631-84309631	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.173C>T; p.T58I; 9:84309698-84309698	liver	carcinoma	Substitution - Missense
c.547C>T; p.L183L; 9:84299703-84299703	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1196C>T; p.A399V; 9:84288132-84288132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1026G>A; p.T342T; 9:84290277-84290277	liver	carcinoma	Substitution - coding silent
c.819T>A; p.F273L; 9:84297263-84297263	breast	carcinoma	Substitution - Missense
c.1062C>A; p.Y354*; 9:84290241-84290241	pleura	pulmonary_blastoma	Substitution - Nonsense
c.1603G>C; p.E535Q; 9:84285389-84285389	breast	carcinoma	Substitution - Missense
c.1360C>T; p.L454L; 9:84286032-84286032	skin	malignant_melanoma	Substitution - coding silent
c.1481C>T; p.S494F; 9:84285511-84285511	skin; neck	malignant_melanoma	Substitution - Missense
c.406G>T; p.V136L; 9:84302318-84302318	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.267A>G; p.T89T; 9:84305321-84305321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.829G>A; p.E277K; 9:84297253-84297253	urinary_tract; bladder	carcinoma	Substitution - Missense
c.131G>A; p.S44N; 9:84313384-84313384	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.159T>A; p.D53E; 9:84309712-84309712	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.491G>A; p.R164K; 9:84302233-84302233	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1756G>T; p.D586Y; 9:84280047-84280047	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1381C>T; p.L461L; 9:84286011-84286011	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1134A>C; p.A378A; 9:84290169-84290169	lung	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]