Entrez Gene

Basic Information
Gene ID	6404
Name	SELPLG
Synonymous	selectin P ligand;SELPLG;selectin P ligand
Definition	P-selectin glycoprotein ligand 1\|cutaneous lymphocyte-associated associated antigen
Position	12q24
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.147A>G; p.L49L; 12:108624161-108624161	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.492T>C; p.T164T; 12:108623786-108623786	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.492T>C; p.T164T; 12:108623786-108623786	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.697A>T; p.T233S; 12:108623581-108623581	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.266G>A; p.R89H; 12:108624042-108624042	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100C>T; p.S367F; 12:108623178-108623178	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.85G>A; p.E29K; 12:108624223-108624223	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.583G>C; p.A195P; 12:108623695-108623695	thyroid	other; neoplasm	Substitution - Missense
c.583G>C; p.A195P; 12:108623695-108623695	thyroid	other; neoplasm	Substitution - Missense
c.437T>C; p.L146P; 12:108623841-108623841	urinary_tract; bladder	carcinoma	Substitution - Missense
c.437T>C; p.L146P; 12:108623841-108623841	urinary_tract; bladder	carcinoma	Substitution - Missense
c.15C>G; p.L5L; 12:108624293-108624293	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - coding silent
c.592G>A; p.A198T; 12:108623686-108623686	central_nervous_system; brain	glioma	Substitution - Missense
c.366G>T; p.Q122H; 12:108623942-108623942	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.581C>T; p.T194I; 12:108623697-108623697	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.976G>A; p.V326M; 12:108623302-108623302	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.391-9C>G; p.?; 12:108623896-108623896	kidney	carcinoma; renal_cell_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	thyroid	other; neoplasm	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.369C>T; p.T123T; 12:108623939-108623939	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.391-9C>G; p.?; 12:108623896-108623896	thyroid	other; neoplasm	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	breast	carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	endometrium	carcinoma; serous_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	kidney	carcinoma; renal_cell_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	kidney	carcinoma; renal_cell_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.391-9C>G; p.?; 12:108623896-108623896	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.590C>A; p.A197E; 12:108623688-108623688	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.612T>C; p.T204T; 12:108623666-108623666	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.664C>A; p.Q222K; 12:108623614-108623614	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.186G>A; p.M62I; 12:108624122-108624122	thyroid	other; neoplasm	Substitution - Missense
c.1033C>T; p.R345C; 12:108623245-108623245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.533G>A; p.G178D; 12:108623745-108623745	skin	malignant_melanoma	Substitution - Missense
c.954G>A; p.A318A; 12:108623324-108623324	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.387G>A; p.T129T; 12:108623921-108623921	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.127delG; p.A43fs*7; 12:108624181-108624181	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.885C>A; p.V295V; 12:108623393-108623393	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.885C>A; p.V295V; 12:108623393-108623393	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.975C>T; p.F325F; 12:108623303-108623303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.329G>A; p.G110E; 12:108623979-108623979	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.97G>A; p.G33S; 12:108624211-108624211	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.391-7C>A; p.?; 12:108623894-108623894	urinary_tract; bladder	carcinoma	Unknown
c.486G>A; p.Q162Q; 12:108623792-108623792	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.739G>C; p.A247P; 12:108623539-108623539	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.995C>T; p.A332V; 12:108623283-108623283	prostate	carcinoma	Substitution - Missense
c.995C>T; p.A332V; 12:108623283-108623283	prostate	carcinoma	Substitution - Missense
c.995C>T; p.A332V; 12:108623283-108623283	prostate	carcinoma	Substitution - Missense
c.995C>T; p.A332V; 12:108623283-108623283	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1121T>C; p.L374P; 12:108623157-108623157	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.583_642del60; p.A195_T214del20; 12:108623636-108623695	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.442G>A; p.A148T; 12:108623836-108623836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.442G>A; p.A148T; 12:108623836-108623836	skin	malignant_melanoma	Substitution - Missense
c.115G>A; p.D39N; 12:108624193-108624193	skin	malignant_melanoma	Substitution - Missense
c.390+6G>T; p.?; 12:108623912-108623912	stomach	carcinoma; adenocarcinoma	Unknown
c.319G>A; p.A107T; 12:108623989-108623989	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.858T>G; p.I286M; 12:108623420-108623420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1196G>T; p.S399I; 12:108623082-108623082	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.114G>A; p.R38R; 12:108624194-108624194	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.646A>C; p.T216P; 12:108623632-108623632	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.600_629del30; p.P205_T214del10; 12:108623649-108623678	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - In frame
c.646A>C; p.T216P; 12:108623632-108623632	urinary_tract; bladder	carcinoma	Substitution - Missense
c.113G>A; p.R38Q; 12:108624195-108624195	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.734C>T; p.P245L; 12:108623544-108623544	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.133G>A; p.E45K; 12:108624175-108624175	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.306G>C; p.L102L; 12:108624002-108624002	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.403C>T; p.P135S; 12:108623875-108623875	skin	malignant_melanoma	Substitution - Missense
c.1139C>T; p.P380L; 12:108623139-108623139	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.391-9C>T; p.?; 12:108623896-108623896	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.311C>T; p.T104M; 12:108623997-108623997	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.365A>G; p.Q122R; 12:108623943-108623943	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.7C>T; p.L3L; 12:108624301-108624301	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.391-4G>A; p.?; 12:108623891-108623891	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.391-4G>A; p.?; 12:108623891-108623891	thyroid	other; neoplasm	Unknown
c.1169G>A; p.R390H; 12:108623109-108623109	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4C>T; p.P2S; 12:108624304-108624304	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1128G>T; p.K376N; 12:108623150-108623150	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.500C>T; p.A167V; 12:108623778-108623778	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.727A>G; p.T243A; 12:108623551-108623551	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.399C>A; p.T133T; 12:108623879-108623879	liver	carcinoma	Substitution - coding silent
c.118C>T; p.R40W; 12:108624190-108624190	pancreas	carcinoma	Substitution - Missense
c.386C>T; p.T129M; 12:108623922-108623922	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.391-11_391-9delTGC; p.?; 12:108623896-108623898	breast	carcinoma	Unknown
c.728C>A; p.T243N; 12:108623550-108623550	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.390+1G>A; p.?; 12:108623917-108623917	liver	carcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.763G>T; p.E255*; 12:108623515-108623515	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.580_581ins30; p.T204_P205ins10; 12:108623697-108623698	lung	carcinoma; non_small_cell_carcinoma	Insertion - In frame
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.390+14_403del30; p.?; 12:108623875-108623904	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.825C>A; p.P275P; 12:108623453-108623453	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.391-10G>A; p.?; 12:108623897-108623897	thyroid	other; neoplasm	Unknown
c.391-10G>A; p.?; 12:108623897-108623897	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.391-10G>A; p.?; 12:108623897-108623897	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.46A>G; p.N16D; 12:108624262-108624262	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.495A>C; p.P165P; 12:108623783-108623783	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.288A>T; p.G96G; 12:108624020-108624020	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.191G>A; p.R64K; 12:108624117-108624117	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.430A>C; p.T144P; 12:108623848-108623848	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.893C>A; p.P298Q; 12:108623385-108623385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.893C>A; p.P298Q; 12:108623385-108623385	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1034G>A; p.R345H; 12:108623244-108623244	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.533G>C; p.G178A; 12:108623745-108623745	thyroid	other; neoplasm	Substitution - Missense
c.1035T>C; p.R345R; 12:108623243-108623243	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.440C>T; p.T147M; 12:108623838-108623838	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.440C>T; p.T147M; 12:108623838-108623838	breast	carcinoma	Substitution - Missense
c.265C>G; p.R89G; 12:108624043-108624043	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.391-10G>C; p.?; 12:108623897-108623897	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.690G>T; p.E230D; 12:108623588-108623588	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.992T>C; p.L331P; 12:108623286-108623286	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.992T>C; p.L331P; 12:108623286-108623286	stomach	adenocarcinoma	Substitution - Missense
c.93C>T; p.A31A; 12:108624215-108624215	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.972C>T; p.F324F; 12:108623306-108623306	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.390+2C>T; p.?; 12:108623916-108623916	liver	carcinoma	Unknown
c.748G>T; p.E250*; 12:108623530-108623530	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.441G>A; p.T147T; 12:108623837-108623837	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.917C>T; p.S306F; 12:108623361-108623361	skin	malignant_melanoma	Substitution - Missense
c.585_586insAA; p.P196fs*113; 12:108623692-108623693	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.758C>T; p.S253F; 12:108623520-108623520	skin	malignant_melanoma	Substitution - Missense
c.441G>A; p.T147T; 12:108623837-108623837	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.392C>T; p.A131V; 12:108623886-108623886	breast	carcinoma	Substitution - Missense
c.1082A>G; p.D361G; 12:108623196-108623196	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.330G>A; p.G110G; 12:108623978-108623978	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.330G>A; p.G110G; 12:108623978-108623978	skin	malignant_melanoma	Substitution - coding silent
c.330G>A; p.G110G; 12:108623978-108623978	skin	malignant_melanoma	Substitution - coding silent
c.1196G>A; p.S399N; 12:108623082-108623082	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1148C>T; p.T383M; 12:108623130-108623130	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.489C>A; p.T163T; 12:108623789-108623789	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.809G>A; p.R270K; 12:108623469-108623469	skin	malignant_melanoma	Substitution - Missense
c.1108G>T; p.A370S; 12:108623170-108623170	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.490A>C; p.T164P; 12:108623788-108623788	urinary_tract; bladder	carcinoma	Substitution - Missense
c.490A>C; p.T164P; 12:108623788-108623788	urinary_tract; bladder	carcinoma	Substitution - Missense
c.201T>G; p.T67T; 12:108624107-108624107	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.919G>A; p.V307M; 12:108623359-108623359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.315G>T; p.E105D; 12:108623993-108623993	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.583delG; p.A195fs*113; 12:108623695-108623695	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.447G>A; p.T149T; 12:108623831-108623831	breast	carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]