| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6392 |
Name | SDHD |
Synonymous | succinate dehydrogenase complex, subunit D, integral membrane protein;SDHD;succinate dehydrogenase complex, subunit D, integral membrane protein |
Definition | succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial|succinate-ubiquinone oxidoreductase cytochrome b small subunit|succinate-ubiquinone reductase membrane anchor subunit |
Position | 11q23 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.291A>T; p.A97A; 11:112088988-112088988 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.10C>T; p.L4F; 11:112086917-112086917 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.479G>T; p.*160L; 11:112094969-112094969 |
skin | malignant_melanoma | Nonstop extension |
c.91A>G; p.I31V; 11:112087895-112087895 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.209G>A; p.R70K; 11:112088906-112088906 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.466C>A; p.L156M; 11:112094956-112094956 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.134G>A; p.G45E; 11:112087938-112087938 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.168T>C; p.H56H; 11:112087972-112087972 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.350G>T; p.G117V; 11:112094840-112094840 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.205G>A; p.E69K; 11:112088902-112088902 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.375G>T; p.K125N; 11:112094865-112094865 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.227T>A; p.L76H; 11:112088924-112088924 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.159G>A; p.P53P; 11:112087963-112087963 |
breast | carcinoma | Substitution - coding silent |
c.207G>A; p.E69E; 11:112088904-112088904 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.376G>T; p.A126S; 11:112094866-112094866 |
skin; ear | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.90T>A; p.H30Q; 11:112087894-112087894 |
liver | carcinoma | Substitution - Missense |
c.200C>T; p.T67I; 11:112088897-112088897 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.216C>T; p.V72V; 11:112088913-112088913 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.139C>T; p.Q47*; 11:112087943-112087943 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.477C>G; p.L159L; 11:112094967-112094967 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.201T>C; p.T67T; 11:112088898-112088898 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.359T>C; p.L120S; 11:112094849-112094849 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.266C>G; p.S89C; 11:112088963-112088963 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.65G>A; p.R22Q; 11:112087869-112087869 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.65G>A; p.R22Q; 11:112087869-112087869 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.65G>A; p.R22Q; 11:112087869-112087869 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.65G>A; p.R22Q; 11:112087869-112087869 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |