| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6035 |
Name | RNASE1 |
Synonymous | ribonuclease, RNase A family, 1 (pancreatic);RNASE1;ribonuclease, RNase A family, 1 (pancreatic) |
Definition | HP-RNase|RIB-1|RNase 1|RNase A|RNase upI-1|ribonuclease 1|ribonuclease A C1|ribonuclease pancreatic |
Position | 14q11.2 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.393G>A; p.E131E; 14:20801676-20801676 |
skin | malignant_melanoma | Substitution - coding silent |
c.44T>C; p.L15P; 14:20802025-20802025 |
skin | malignant_melanoma | Substitution - Missense |
c.286G>T; p.G96W; 14:20801783-20801783 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.171G>A; p.M57I; 14:20801898-20801898 |
skin | malignant_melanoma | Substitution - Missense |
c.193C>T; p.Q65*; 14:20801876-20801876 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.319A>T; p.M107L; 14:20801750-20801750 |
skin | malignant_melanoma | Substitution - Missense |
c.246C>T; p.V82V; 14:20801823-20801823 |
skin | malignant_melanoma | Substitution - coding silent |
c.228C>T; p.H76H; 14:20801841-20801841 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.187A>G; p.M63V; 14:20801882-20801882 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.225G>A; p.V75V; 14:20801844-20801844 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.225G>A; p.V75V; 14:20801844-20801844 |
thyroid | carcinoma | Substitution - coding silent |
c.447T>C; p.D149D; 14:20801622-20801622 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.191C>T; p.T64I; 14:20801878-20801878 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.255_258delCTGT; p.C86fs*28; 14:20801811-20801814 |
lung | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.423C>A; p.S141R; 14:20801646-20801646 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.41T>C; p.V14A; 14:20802028-20802028 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.228C>A; p.H76Q; 14:20801841-20801841 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.183G>A; p.R61R; 14:20801886-20801886 |
skin | malignant_melanoma | Substitution - coding silent |
c.142A>C; p.S48R; 14:20801927-20801927 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.95G>A; p.R32Q; 14:20801974-20801974 |
central_nervous_system; brain | primitive_neuroectodermal_tumour-medulloblastoma | Substitution - Missense |
c.411C>A; p.A137A; 14:20801658-20801658 |
liver | carcinoma | Substitution - coding silent |
c.411C>A; p.A137A; 14:20801658-20801658 |
liver | carcinoma | Substitution - coding silent |
c.111G>A; p.Q37Q; 14:20801958-20801958 |
upper_aerodigestive_tract; larynx | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.387G>A; p.P129P; 14:20801682-20801682 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.387G>A; p.P129P; 14:20801682-20801682 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - coding silent |
c.87G>A; p.K29K; 14:20801982-20801982 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |