Entrez Gene

Basic Information
Gene ID	6019
Name	RLN2
Synonymous	relaxin 2;RLN2;relaxin 2
Definition	H2-preprorelaxin\|prorelaxin H2\|relaxin, ovarian, of pregnancy
Position	9p24.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.294G>A; p.L98L; 9:5300362-5300362	breast	carcinoma	Substitution - coding silent
c.420C>T; p.A140A; 9:5300236-5300236	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.460G>T; p.D154Y; 9:5300196-5300196	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.20_21insT; p.H8fs*26; 9:5304560-5304561	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.398T>C; p.I133T; 9:5300258-5300258	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.375C>G; p.L125L; 9:5300281-5300281	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.412A>T; p.S138C; 9:5300244-5300244	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.412A>T; p.S138C; 9:5300244-5300244	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.401G>A; p.R134H; 9:5300255-5300255	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.401G>A; p.R134H; 9:5300255-5300255	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.262T>C; p.S88P; 9:5300394-5300394	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.87G>C; p.E29D; 9:5304494-5304494	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.394C>A; p.L132I; 9:5300262-5300262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.455G>T; p.G152V; 9:5300201-5300201	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.387T>A; p.F129L; 9:5300269-5300269	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.310G>C; p.E104Q; 9:5300346-5300346	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.482G>T; p.R161I; 9:5300174-5300174	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.528T>C; p.C176C; 9:5300128-5300128	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.401G>T; p.R134L; 9:5300255-5300255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.190C>T; p.Q64*; 9:5304391-5304391	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.512G>A; p.C171Y; 9:5300144-5300144	breast	carcinoma	Substitution - Missense
c.310G>A; p.E104K; 9:5300346-5300346	breast	carcinoma	Substitution - Missense
c.125C>T; p.A42V; 9:5304456-5304456	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.537A>G; p.R179R; 9:5300119-5300119	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.537A>G; p.R179R; 9:5300119-5300119	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.54A>C; p.Q18H; 9:5304527-5304527	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.269T>G; p.F90C; 9:5300387-5300387	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.470C>T; p.S157F; 9:5300186-5300186	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.421G>T; p.A141S; 9:5300235-5300235	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.308C>T; p.S103F; 9:5300348-5300348	skin	malignant_melanoma	Substitution - Missense
c.21_22insT; p.H8fs*26; 9:5304559-5304560	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.106G>C; p.G36R; 9:5304475-5304475	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.400C>T; p.R134C; 9:5300256-5300256	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>T; p.P145L; 9:5300222-5300222	urinary_tract; bladder	carcinoma	Substitution - Missense
c.84_85GG>AA; p.M28_E29>IK; 9:5304496-5304497	skin; head_neck	carcinoma; squamous_cell_carcinoma	Complex - compound substitution
c.480G>T; p.K160N; 9:5300176-5300176	breast	carcinoma	Substitution - Missense
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20delT; p.F7fs*4; 9:5304561-5304561	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift

COSMIC somatic mutation [Top]