| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5997 |
Name | RGS2 |
Synonymous | regulator of G-protein signaling 2;RGS2;regulator of G-protein signaling 2 |
Definition | G0 to G1 switch regulatory 8, 24kD|G0/G1 switch regulatory protein 8|cell growth-inhibiting gene 31 protein|cell growth-inhibiting protein 31|regulator of G-protein signaling 2, 24kDa |
Position | 1q31 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.247G>T; p.A83S; 1:192810404-192810404 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.357C>G; p.F119L; 1:192811063-192811063 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.365C>A; p.T122N; 1:192811071-192811071 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.595T>A; p.C199S; 1:192811555-192811555 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.4C>A; p.Q2K; 1:192809075-192809075 |
oesophagus | carcinoma | Substitution - Missense |
c.4C>T; p.Q2*; 1:192809075-192809075 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.302T>C; p.L101S; 1:192811008-192811008 |
skin | malignant_melanoma | Substitution - Missense |
c.274+2_274+6delTAAGT; p.?; 1:192810433-192810437 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Unknown |
c.306G>A; p.K102K; 1:192811012-192811012 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.589G>T; p.D197Y; 1:192811549-192811549 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.150A>G; p.Q50Q; 1:192810205-192810205 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.183_184insA; p.S64fs*12; 1:192810238-192810239 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Insertion - Frameshift |
c.300T>G; p.F100L; 1:192811006-192811006 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.371C>A; p.S124*; 1:192811077-192811077 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.6A>T; p.Q2H; 1:192809077-192809077 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.288A>G; p.A96A; 1:192810994-192810994 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.563G>A; p.R188H; 1:192811523-192811523 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.184delA; p.S64fs*25; 1:192810239-192810239 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.184delA; p.S64fs*25; 1:192810239-192810239 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.184delA; p.S64fs*25; 1:192810239-192810239 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.184delA; p.S64fs*25; 1:192810239-192810239 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.583T>A; p.Y195N; 1:192811543-192811543 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.41G>T; p.R14I; 1:192809112-192809112 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.315C>A; p.F105L; 1:192811021-192811021 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.315C>A; p.F105L; 1:192811021-192811021 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.349G>C; p.E117Q; 1:192811055-192811055 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.397A>G; p.R133G; 1:192811103-192811103 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.181G>A; p.G61S; 1:192810236-192810236 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |