Entrez Gene

Basic Information
Gene ID	5962
Name	RDX
Synonymous	radixin;RDX;radixin
Definition	-
Position	11q23
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.370C>A; p.L124I; 11:110264057-110264057	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.877C>T; p.R293*; 11:110254028-110254028	pancreas	carcinoma	Substitution - Nonsense
c.1433T>C; p.V478A; 11:110233391-110233391	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.960-1G>A; p.?; 11:110247834-110247834	oesophagus	carcinoma; adenocarcinoma	Unknown
c.217G>A; p.E73K; 11:110264210-110264210	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.217G>A; p.E73K; 11:110264210-110264210	skin; extremity	malignant_melanoma	Substitution - Missense
c.18C>T; p.N6N; 11:110272614-110272614	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1549G>A; p.E517K; 11:110233275-110233275	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1252-1G>A; p.?; 11:110236192-110236192	lung	carcinoma; small_cell_carcinoma	Unknown
c.514A>C; p.I172L; 11:110258143-110258143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1226A>T; p.D409V; 11:110237517-110237517	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.419A>C; p.E140A; 11:110264008-110264008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1513G>A; p.V505I; 11:110233311-110233311	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1301C>T; p.A434V; 11:110236142-110236142	liver	carcinoma	Substitution - Missense
c.346T>C; p.Y116H; 11:110264081-110264081	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.160G>T; p.G54C; 11:110264811-110264811	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1493C>T; p.A498V; 11:110233331-110233331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.252C>G; p.F84L; 11:110264175-110264175	breast	carcinoma	Substitution - Missense
c.657T>G; p.G219G; 11:110257808-110257808	breast	carcinoma	Substitution - coding silent
c.489A>C; p.L163L; 11:110258168-110258168	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.234C>G; p.F78L; 11:110264193-110264193	urinary_tract; bladder	carcinoma	Substitution - Missense
c.215A>T; p.K72I; 11:110264212-110264212	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1495G>C; p.E499Q; 11:110233329-110233329	breast	carcinoma	Substitution - Missense
c.1253C>T; p.A418V; 11:110236190-110236190	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.915G>A; p.M305I; 11:110253990-110253990	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1253C>T; p.A418V; 11:110236190-110236190	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.872A>G; p.Y291C; 11:110254033-110254033	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.920C>T; p.A307V; 11:110253985-110253985	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.306C>A; p.F102L; 11:110264121-110264121	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.699-4delT; p.?; 11:110255389-110255389	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.699-4delT; p.?; 11:110255389-110255389	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.933G>A; p.E311E; 11:110253972-110253972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.733A>G; p.I245V; 11:110255351-110255351	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1163G>A; p.R388Q; 11:110237580-110237580	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.666T>G; p.A222A; 11:110257799-110257799	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1726C>T; p.R576C; 11:110231895-110231895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.761A>C; p.K254T; 11:110255323-110255323	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 11:110247745-110247745	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.166T>C; p.S56P; 11:110264805-110264805	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1468G>A; p.D490N; 11:110233356-110233356	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.612C>T; p.N204N; 11:110257853-110257853	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.259G>A; p.E87K; 11:110264168-110264168	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.898A>G; p.I300V; 11:110254007-110254007	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1269A>C; p.E423D; 11:110236174-110236174	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1438C>T; p.P480S; 11:110233386-110233386	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.836G>A; p.R279Q; 11:110254069-110254069	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.836G>A; p.R279Q; 11:110254069-110254069	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.836G>A; p.R279Q; 11:110254069-110254069	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.836G>A; p.R279Q; 11:110254069-110254069	skin	malignant_melanoma	Substitution - Missense
c.1522C>T; p.H508Y; 11:110233302-110233302	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1522C>T; p.H508Y; 11:110233302-110233302	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1547C>T; p.T516I; 11:110233277-110233277	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.709A>C; p.K237Q; 11:110255375-110255375	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.737G>A; p.R246K; 11:110255347-110255347	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.709A>C; p.K237Q; 11:110255375-110255375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.273G>T; p.E91D; 11:110264154-110264154	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1117C>G; p.L373V; 11:110237626-110237626	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.6G>T; p.P2P; 11:110279687-110279687	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.906A>G; p.V302V; 11:110253999-110253999	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.628A>C; p.N210H; 11:110257837-110257837	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1373A>G; p.K458R; 11:110233451-110233451	central_nervous_system; brain	glioma	Substitution - Missense
c.878G>A; p.R293Q; 11:110254027-110254027	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1691C>G; p.T564S; 11:110231930-110231930	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.267T>G; p.V89V; 11:110264160-110264160	central_nervous_system; brain	glioma	Substitution - coding silent
c.711A>C; p.K237N; 11:110255373-110255373	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.96G>A; p.Q32Q; 11:110272536-110272536	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1412_1413insC; p.P472fs*16; 11:110233411-110233412	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.687G>A; p.E229E; 11:110257778-110257778	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1585C>T; p.Q529*; 11:110233239-110233239	ovary	carcinoma	Substitution - Nonsense
c.1585C>T; p.Q529*; 11:110233239-110233239	ovary	carcinoma	Substitution - Nonsense
c.322G>A; p.E108K; 11:110264105-110264105	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.773A>C; p.K258T; 11:110255311-110255311	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1705C>T; p.R569*; 11:110231916-110231916	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1412delC; p.P471fs*35; 11:110233412-110233412	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1006G>A; p.E336K; 11:110247787-110247787	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.779T>C; p.I260T; 11:110255305-110255305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1444A>G; p.T482A; 11:110233380-110233380	skin	malignant_melanoma	Substitution - Missense
c.818G>A; p.R273H; 11:110254087-110254087	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1227C>T; p.D409D; 11:110237516-110237516	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.135delT; p.F45fs*6; 11:110264836-110264836	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1177C>T; p.R393C; 11:110237566-110237566	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.252C>T; p.F84F; 11:110264175-110264175	skin	malignant_melanoma	Substitution - coding silent
c.1109G>A; p.R370Q; 11:110237634-110237634	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.344T>C; p.I115T; 11:110264083-110264083	breast	carcinoma	Substitution - Missense
c.322G>T; p.E108*; 11:110264105-110264105	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1366T>G; p.L456V; 11:110233458-110233458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.322G>T; p.E108*; 11:110264105-110264105	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1181G>A; p.R394Q; 11:110237562-110237562	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1293A>T; p.L431L; 11:110236150-110236150	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1363G>T; p.D455Y; 11:110233461-110233461	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.901G>A; p.E301K; 11:110254004-110254004	skin	malignant_melanoma	Substitution - Missense
c.1207A>G; p.I403V; 11:110237536-110237536	liver	carcinoma	Substitution - Missense
c.1207A>G; p.I403V; 11:110237536-110237536	liver	carcinoma	Substitution - Missense
c.1420C>T; p.P474S; 11:110233404-110233404	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.549A>T; p.L183F; 11:110258108-110258108	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1188T>C; p.A396A; 11:110237555-110237555	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.188A>C; p.K63T; 11:110264783-110264783	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.295C>T; p.Q99*; 11:110264132-110264132	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.1533G>A; p.E511E; 11:110233291-110233291	pancreas	carcinoma	Substitution - coding silent
c.1588-5A>G; p.?; 11:110232038-110232038	liver	carcinoma	Unknown
c.1588-5A>G; p.?; 11:110232038-110232038	liver	carcinoma	Unknown
c.1555_1556delCA; p.Q519fs*3; 11:110233268-110233269	soft_tissue; blood_vessel	angiosarcoma	Deletion - Frameshift
c.1024C>T; p.R342C; 11:110247769-110247769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.286G>T; p.E96*; 11:110264141-110264141	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1016G>T; p.R339I; 11:110247777-110247777	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]