Entrez Gene

Basic Information
Gene ID	59348
Name	ZNF350
Synonymous	zinc finger protein 350;ZNF350;zinc finger protein 350
Definition	KRAB zinc finger protein ZFQR\|zinc finger and BRCA1-interacting protein with a KRAB domain 1\|zinc finger protein ZBRK1\|zinc-finger protein ZBRK1
Position	19q13.41
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.105T>C; p.D35D; 19:51969042-51969042	thyroid	other; neoplasm	Substitution - coding silent
c.102G>A; p.R34R; 19:51969045-51969045	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.44T>G; p.V15G; 19:51969103-51969103	breast	carcinoma	Substitution - Missense
c.1576T>C; p.F526L; 19:51964877-51964877	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1576T>C; p.F526L; 19:51964877-51964877	stomach	adenocarcinoma	Substitution - Missense
c.1568A>G; p.Y523C; 19:51964885-51964885	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1415C>T; p.S472L; 19:51965038-51965038	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1278G>A; p.R426R; 19:51965175-51965175	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1415C>T; p.S472L; 19:51965038-51965038	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.21C>G; p.S7S; 19:51969126-51969126	breast	carcinoma	Substitution - coding silent
c.1019A>G; p.H340R; 19:51965434-51965434	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.647T>A; p.I216N; 19:51965806-51965806	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.929G>A; p.R310Q; 19:51965524-51965524	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1298A>C; p.K433T; 19:51965155-51965155	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.929G>A; p.R310Q; 19:51965524-51965524	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.929G>A; p.R310Q; 19:51965524-51965524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1119C>T; p.P373P; 19:51965334-51965334	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1570G>A; p.V524I; 19:51964883-51964883	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1059A>G; p.K353K; 19:51965394-51965394	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.85C>T; p.Q29*; 19:51969062-51969062	breast	carcinoma	Substitution - Nonsense
c.798_826>TTT; p.E266fs*20; 19:51965627-51965655	breast	carcinoma; ductal_carcinoma	Complex - frameshift
c.798_826>TTT; p.E266fs*20; 19:51965627-51965655	breast	carcinoma; ductal_carcinoma	Complex - frameshift
c.1309C>T; p.P437S; 19:51965144-51965144	skin; leg	malignant_melanoma	Substitution - Missense
c.1309C>T; p.P437S; 19:51965144-51965144	skin; leg	malignant_melanoma	Substitution - Missense
c.201G>C; p.W67C; 19:51968615-51968615	breast	carcinoma	Substitution - Missense
c.56G>A; p.W19*; 19:51969091-51969091	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.237A>G; p.S79S; 19:51968579-51968579	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1256A>G; p.K419R; 19:51965197-51965197	skin	malignant_melanoma	Substitution - Missense
c.985C>T; p.Q329*; 19:51965468-51965468	breast	carcinoma	Substitution - Nonsense
c.1111G>T; p.E371*; 19:51965342-51965342	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.601A>C; p.K201Q; 19:51965852-51965852	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1376G>A; p.G459E; 19:51965077-51965077	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.190G>A; p.E64K; 19:51968626-51968626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1392G>T; p.V464V; 19:51965061-51965061	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.85C>G; p.Q29E; 19:51969062-51969062	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.648C>A; p.I216I; 19:51965805-51965805	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.869A>G; p.Y290C; 19:51965584-51965584	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.656C>A; p.S219Y; 19:51965797-51965797	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.490T>A; p.F164I; 19:51965963-51965963	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.511C>T; p.R171*; 19:51965942-51965942	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.859G>A; p.E287K; 19:51965594-51965594	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.202A>G; p.T68A; 19:51968614-51968614	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1450G>A; p.V484I; 19:51965003-51965003	pancreas	carcinoma	Substitution - Missense
c.761G>A; p.R254Q; 19:51965692-51965692	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.598C>T; p.R200*; 19:51965855-51965855	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.33G>T; p.E11D; 19:51969114-51969114	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.33G>A; p.E11E; 19:51969114-51969114	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1186C>T; p.H396Y; 19:51965267-51965267	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.376C>T; p.H126Y; 19:51966077-51966077	skin	malignant_melanoma	Substitution - Missense
c.1229C>T; p.A410V; 19:51965224-51965224	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1234G>T; p.A412S; 19:51965219-51965219	breast	carcinoma	Substitution - Missense
c.1374C>T; p.N458N; 19:51965079-51965079	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1258C>G; p.H420D; 19:51965195-51965195	pancreas	carcinoma	Substitution - Missense
c.651G>C; p.K217N; 19:51965802-51965802	breast	carcinoma	Substitution - Missense
c.169C>T; p.L57F; 19:51968647-51968647	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.496C>T; p.H166Y; 19:51965957-51965957	skin	malignant_melanoma	Substitution - Missense
c.1230G>A; p.A410A; 19:51965223-51965223	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1230G>A; p.A410A; 19:51965223-51965223	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1200A>T; p.R400S; 19:51965253-51965253	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.866C>A; p.P289H; 19:51965587-51965587	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.318T>C; p.H106H; 19:51966135-51966135	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.512G>A; p.R171Q; 19:51965941-51965941	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.512G>A; p.R171Q; 19:51965941-51965941	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.955A>G; p.I319V; 19:51965498-51965498	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1435C>T; p.L479F; 19:51965018-51965018	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1435C>T; p.L479F; 19:51965018-51965018	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.676G>A; p.V226I; 19:51965777-51965777	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.764C>G; p.T255S; 19:51965689-51965689	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.950C>T; p.P317L; 19:51965503-51965503	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Substitution - Missense
c.937A>G; p.T313A; 19:51965516-51965516	prostate	carcinoma	Substitution - Missense
c.561T>C; p.T187T; 19:51965892-51965892	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1029G>T; p.K343N; 19:51965424-51965424	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.24A>G; p.I8M; 19:51969123-51969123	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1067C>A; p.S356Y; 19:51965386-51965386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733A>G; p.R245G; 19:51965720-51965720	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1510G>T; p.A504S; 19:51964943-51964943	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.731C>T; p.S244F; 19:51965722-51965722	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.60G>A; p.E20E; 19:51969087-51969087	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.291G>C; p.V97V; 19:51966162-51966162	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.161C>G; p.P54R; 19:51968655-51968655	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.517C>T; p.H173Y; 19:51965936-51965936	skin	malignant_melanoma	Substitution - Missense
c.1518C>T; p.D506D; 19:51964935-51964935	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.517C>T; p.H173Y; 19:51965936-51965936	skin	malignant_melanoma	Substitution - Missense
c.67C>A; p.Q23K; 19:51969080-51969080	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1097G>T; p.R366I; 19:51965356-51965356	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.626G>A; p.S209N; 19:51965827-51965827	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1097G>T; p.R366I; 19:51965356-51965356	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1397C>T; p.S466F; 19:51965056-51965056	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.708T>C; p.C236C; 19:51965745-51965745	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.161C>T; p.P54L; 19:51968655-51968655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1558G>A; p.V520M; 19:51964895-51964895	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1153A>G; p.T385A; 19:51965300-51965300	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.304C>T; p.P102S; 19:51966149-51966149	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.826C>T; p.R276W; 19:51965627-51965627	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.679A>T; p.M227L; 19:51965774-51965774	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1524C>T; p.N508N; 19:51964929-51964929	skin	malignant_melanoma	Substitution - coding silent
c.1524C>T; p.N508N; 19:51964929-51964929	skin	malignant_melanoma	Substitution - coding silent
c.426A>G; p.L142L; 19:51966027-51966027	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]