Entrez Gene

Basic Information
Gene ID	5916
Name	RARG
Synonymous	retinoic acid receptor, gamma;RARG;retinoic acid receptor, gamma
Definition	RAR-gamma\|nuclear receptor subfamily 1 group B member 3\|retinoic acid nuclear receptor gamma variant 1\|retinoic acid nuclear receptor gamma variant 2\|retinoic acid receptor gamma
Position	12q13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.858G>C; p.M286I; 12:53213656-53213656	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1221G>A; p.P407P; 12:53211820-53211820	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.655C>T; p.R219C; 12:53214217-53214217	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.979G>A; p.E327K; 12:53213535-53213535	urinary_tract; bladder	carcinoma	Substitution - Missense
c.746C>T; p.P249L; 12:53214126-53214126	skin	malignant_melanoma	Substitution - Missense
c.207C>T; p.S69S; 12:53215772-53215772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.588C>T; p.A196A; 12:53214494-53214494	liver	carcinoma	Substitution - coding silent
c.295G>A; p.G99S; 12:53215684-53215684	skin	malignant_melanoma	Substitution - Missense
c.20G>A; p.R7Q; 12:53227526-53227526	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.475G>A; p.A159T; 12:53215293-53215293	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.475G>A; p.A159T; 12:53215293-53215293	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.245C>T; p.P82L; 12:53215734-53215734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1017A>T; p.G339G; 12:53213497-53213497	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.740G>C; p.R247P; 12:53214132-53214132	urinary_tract; bladder	carcinoma	Substitution - Missense
c.740G>C; p.R247P; 12:53214132-53214132	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.870C>T; p.D290D; 12:53213644-53213644	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.64G>T; p.G22W; 12:53227482-53227482	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1288G>A; p.G430S; 12:53211753-53211753	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1288G>A; p.G430S; 12:53211753-53211753	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.866C>T; p.S289F; 12:53213648-53213648	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1203G>T; p.K401N; 12:53211838-53211838	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.136T>G; p.F46V; 12:53227410-53227410	skin	malignant_melanoma	Substitution - Missense
c.343C>T; p.R115C; 12:53215425-53215425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.244C>T; p.P82S; 12:53215735-53215735	skin	malignant_melanoma	Substitution - Missense
c.1032G>A; p.L344L; 12:53213230-53213230	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1019-1G>A; p.?; 12:53213244-53213244	urinary_tract; bladder	carcinoma	Unknown
c.1091A>G; p.Y364C; 12:53213171-53213171	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.278G>A; p.C93Y; 12:53215701-53215701	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.789C>G; p.L263L; 12:53214083-53214083	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.405C>T; p.N135N; 12:53215363-53215363	central_nervous_system; brain	glioma	Substitution - coding silent
c.890C>G; p.T297S; 12:53213624-53213624	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.937G>C; p.A313P; 12:53213577-53213577	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.842delC; p.P281fs*6; 12:53213672-53213672	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1130C>T; p.P377L; 12:53213132-53213132	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1103G>A; p.R368Q; 12:53213159-53213159	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1103G>A; p.R368Q; 12:53213159-53213159	pancreas	carcinoma	Substitution - Missense
c.383G>A; p.R128H; 12:53215385-53215385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1042G>A; p.E348K; 12:53213220-53213220	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.19C>T; p.R7*; 12:53227527-53227527	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.19C>T; p.R7*; 12:53227527-53227527	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1153G>T; p.D385Y; 12:53213109-53213109	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.30G>A; p.A10A; 12:53227516-53227516	skin	malignant_melanoma	Substitution - coding silent
c.700G>C; p.A234P; 12:53214172-53214172	urinary_tract; bladder	carcinoma	Substitution - Missense
c.809T>C; p.I270T; 12:53214063-53214063	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.567C>T; p.L189L; 12:53214515-53214515	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.150C>G; p.G50G; 12:53227396-53227396	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.567C>A; p.L189L; 12:53214515-53214515	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.567C>A; p.L189L; 12:53214515-53214515	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.642C>T; p.S214S; 12:53214230-53214230	skin	malignant_melanoma	Substitution - coding silent
c.488A>T; p.D163V; 12:53214594-53214594	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.620T>C; p.L207P; 12:53214462-53214462	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1122C>T; p.Y374Y; 12:53213140-53213140	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.347G>A; p.R116Q; 12:53215421-53215421	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.99C>T; p.L33L; 12:53227447-53227447	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.427C>T; p.Q143*; 12:53215341-53215341	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.754A>G; p.T252A; 12:53214118-53214118	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1324C>T; p.P442S; 12:53211717-53211717	skin	malignant_melanoma	Substitution - Missense
c.1085G>A; p.R362K; 12:53213177-53213177	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.131C>T; p.P44L; 12:53227415-53227415	skin	malignant_melanoma	Substitution - Missense
c.309G>T; p.G103G; 12:53215670-53215670	prostate	adenoma	Substitution - coding silent
c.378T>G; p.C126W; 12:53215390-53215390	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.378T>G; p.C126W; 12:53215390-53215390	urinary_tract; bladder	carcinoma	Substitution - Missense
c.254G>A; p.R85Q; 12:53215725-53215725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.608C>T; p.S203L; 12:53214474-53214474	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.873G>A; p.G291G; 12:53213641-53213641	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1289G>A; p.G430D; 12:53211752-53211752	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.914G>A; p.G305E; 12:53213600-53213600	breast	carcinoma	Substitution - Missense
c.1019-4A>T; p.?; 12:53213247-53213247	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Unknown
c.454G>A; p.E152K; 12:53215314-53215314	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.454G>A; p.E152K; 12:53215314-53215314	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.745C>T; p.P249S; 12:53214127-53214127	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.145C>T; p.L49L; 12:53227401-53227401	skin	malignant_melanoma	Substitution - coding silent
c.725T>C; p.V242A; 12:53214147-53214147	urinary_tract; bladder	carcinoma	Substitution - Missense
c.922A>T; p.T308S; 12:53213592-53213592	urinary_tract; bladder	carcinoma	Substitution - Missense
c.922A>T; p.T308S; 12:53213592-53213592	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1021C>T; p.R341C; 12:53213241-53213241	breast	carcinoma	Substitution - Missense
c.261C>G; p.Y87*; 12:53215718-53215718	breast	carcinoma	Substitution - Nonsense
c.954C>T; p.L318L; 12:53213560-53213560	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.961C>G; p.L321V; 12:53213553-53213553	urinary_tract; bladder	carcinoma	Substitution - Missense
c.384C>T; p.R128R; 12:53215384-53215384	prostate	carcinoma	Substitution - coding silent
c.384C>T; p.R128R; 12:53215384-53215384	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.729G>A; p.E243E; 12:53214143-53214143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1016G>T; p.G339V; 12:53213498-53213498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100G>A; p.R367H; 12:53213162-53213162	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.853A>G; p.T285A; 12:53213661-53213661	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1311C>G; p.S437R; 12:53211730-53211730	urinary_tract; bladder	carcinoma	Substitution - Missense
c.83_84CC>TT; p.A28V; 12:53227462-53227463	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.677T>G; p.L226R; 12:53214195-53214195	skin	malignant_melanoma	Substitution - Missense
c.520G>A; p.E174K; 12:53214562-53214562	urinary_tract; bladder	carcinoma	Substitution - Missense
c.948_955delGCAGCTCC; p.Q317fs*6; 12:53213559-53213566	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Deletion - Frameshift
c.481C>T; p.R161*; 12:53214601-53214601	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense

COSMIC somatic mutation [Top]