Entrez Gene

Basic Information
Gene ID	5908
Name	RAP1B
Synonymous	RAP1B, member of RAS oncogene family;RAP1B;RAP1B, member of RAS oncogene family
Definition	GTP-binding protein smg p21B\|RAS-related protein RAP1B\|Ras family small GTP binding protein RAP1B\|ras-related protein Rap-1b\|small GTP binding protein
Position	12q14
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.50C>G; p.S17C; 12:68648774-68648774	breast	carcinoma	Substitution - Missense
c.48G>A; p.K16K; 12:68648772-68648772	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.35G>A; p.G12E; 12:68648759-68648759	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.35G>A; p.G12E; 12:68648759-68648759	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.35G>A; p.G12E; 12:68648759-68648759	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.509C>T; p.P170L; 12:68657141-68657141	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.236C>T; p.A79V; 12:68654164-68654164	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.108A>T; p.I36I; 12:68650450-68650450	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.25C>T; p.L9F; 12:68648749-68648749	breast	carcinoma	Substitution - Missense
c.8A>G; p.E3G; 12:68648732-68648732	urinary_tract; bladder	carcinoma	Substitution - Missense
c.369A>G; p.E123E; 12:68656350-68656350	skin	malignant_melanoma	Substitution - coding silent
c.76G>T; p.G26*; 12:68650418-68650418	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.4C>T; p.R2C; 12:68648728-68648728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.304C>T; p.R102*; 12:68654232-68654232	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4C>T; p.R2C; 12:68648728-68648728	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.101C>A; p.P34H; 12:68650443-68650443	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.489G>A; p.R163R; 12:68657121-68657121	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.201G>A; p.M67I; 12:68654129-68654129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.104C>T; p.T35M; 12:68650446-68650446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.518G>T; p.G173V; 12:68657150-68657150	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.109G>C; p.E37Q; 12:68650451-68650451	urinary_tract; bladder	carcinoma	Substitution - Missense
c.527G>A; p.R176H; 12:68657159-68657159	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.343G>T; p.G115C; 12:68656324-68656324	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.38G>A; p.G13D; 12:68648762-68648762	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.38G>A; p.G13D; 12:68648762-68648762	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>T; p.Y32Y; 12:68650438-68650438	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.305G>A; p.R102Q; 12:68654233-68654233	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.214A>G; p.M72V; 12:68654142-68654142	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.40G>T; p.V14F; 12:68648764-68648764	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.100_101CC>TT; p.P34F; 12:68650442-68650443	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.73C>G; p.Q25E; 12:68650415-68650415	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.65A>G; p.Q22R; 12:68650407-68650407	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.121A>G; p.R41G; 12:68650463-68650463	kidney	other; neoplasm	Substitution - Missense
c.14A>G; p.K5R; 12:68648738-68648738	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.39C>T; p.G13G; 12:68648763-68648763	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.213C>T; p.Y71Y; 12:68654141-68654141	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.39C>T; p.G13G; 12:68648763-68648763	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.230G>T; p.G77V; 12:68654158-68654158	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.34G>A; p.G12R; 12:68648758-68648758	salivary_gland	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.550C>T; p.L184F; 12:68657182-68657182	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]