| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5873 |
Name | RAB27A |
Synonymous | RAB27A, member RAS oncogene family;RAB27A;RAB27A, member RAS oncogene family |
Definition | GTP-binding protein Ram|rab-27|ras-related protein Rab-27A |
Position | 15q15-q21.1 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.599G>A; p.R200Q; 15:55205574-55205574 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.473C>T; p.P158L; 15:55205700-55205700 |
skin; scalp | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.473C>T; p.P158L; 15:55205700-55205700 |
skin | malignant_melanoma | Substitution - Missense |
c.535G>T; p.D179Y; 15:55205638-55205638 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.426A>T; p.V142V; 15:55223930-55223930 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - coding silent |
c.149G>T; p.R50I; 15:55234786-55234786 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.559C>T; p.R187W; 15:55205614-55205614 |
thyroid | carcinoma | Substitution - Missense |
c.583C>T; p.P195S; 15:55205590-55205590 |
skin | malignant_melanoma | Substitution - Missense |
c.148delA; p.R50fs*35; 15:55234787-55234787 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.315A>G; p.Q105Q; 15:55228637-55228637 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.156G>T; p.V52V; 15:55230484-55230484 |
oesophagus | carcinoma; adenocarcinoma | Substitution - coding silent |
c.446T>C; p.I149T; 15:55223910-55223910 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.221A>T; p.D74V; 15:55230419-55230419 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.493G>T; p.A165S; 15:55205680-55205680 |
thyroid | other; neoplasm | Substitution - Missense |
c.610C>T; p.H204Y; 15:55205563-55205563 |
breast | carcinoma | Substitution - Missense |
c.520A>C; p.I174L; 15:55205653-55205653 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.615C>T; p.A205A; 15:55205558-55205558 |
skin | malignant_melanoma | Substitution - coding silent |
c.468-1G>T; p.?; 15:55205706-55205706 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.1A>G; p.M1V; 15:55234934-55234934 |
liver | carcinoma | Substitution - Missense |
c.598C>T; p.R200*; 15:55205575-55205575 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.1A>G; p.M1V; 15:55234934-55234934 |
liver | carcinoma | Substitution - Missense |
c.556G>T; p.E186*; 15:55205617-55205617 |
thyroid | carcinoma | Substitution - Nonsense |
c.273T>G; p.D91E; 15:55228679-55228679 |
skin | malignant_melanoma | Substitution - Missense |
c.642G>T; p.K214N; 15:55205531-55205531 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.551G>A; p.R184Q; 15:55205622-55205622 |
central_nervous_system; brain | glioma | Substitution - Missense |
c.236A>G; p.E79G; 15:55230404-55230404 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.239G>A; p.R80K; 15:55230401-55230401 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.254C>T; p.T85M; 15:55228698-55228698 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.453C>A; p.L151L; 15:55223903-55223903 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.621G>A; p.T207T; 15:55205552-55205552 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.634G>T; p.E212*; 15:55205539-55205539 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.502A>G; p.T168A; 15:55205671-55205671 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.250T>C; p.L84L; 15:55228702-55228702 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.548A>C; p.K183T; 15:55205625-55205625 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.454G>A; p.A152T; 15:55223902-55223902 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.630A>T; p.L210F; 15:55205543-55205543 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.630A>T; p.L210F; 15:55205543-55205543 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.630A>T; p.L210F; 15:55205543-55205543 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.445A>G; p.I149V; 15:55223911-55223911 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.188G>A; p.G63D; 15:55230452-55230452 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.32A>G; p.K11R; 15:55234903-55234903 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.202A>T; p.I68F; 15:55230438-55230438 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |