Entrez Gene

Basic Information
Gene ID	5552
Name	SRGN
Synonymous	serglycin;SRGN;serglycin
Definition	hematopoetic proteoglycan core peptide\|hematopoetic proteoglycan core protein\|hematopoietic proteoglycan core protein\|p.PG\|platelet proteoglycan core protein\|proteoglycan 1, secretory granule\|proteoglycan protein core for mast cell secretory granule\|secre
Position	10q22.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.132T>C; p.S44S; 10:69097136-69097136	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.299C>G; p.S100C; 10:69103942-69103942	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.293_294insCGGCTC; p.G111_F112insSG; 10:69103936-69103937	large_intestine	carcinoma; adenocarcinoma	Insertion - In frame
c.373G>A; p.E125K; 10:69104016-69104016	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.379G>A; p.D127N; 10:69104022-69104022	urinary_tract; bladder	carcinoma	Substitution - Missense
c.431G>A; p.S144N; 10:69104074-69104074	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.343G>A; p.E115K; 10:69103986-69103986	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.222T>C; p.L74L; 10:69097226-69097226	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.296G>T; p.G99V; 10:69103939-69103939	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.452G>A; p.G151E; 10:69104095-69104095	skin	malignant_melanoma	Substitution - Missense
c.112G>A; p.V38M; 10:69097116-69097116	skin; trunk	malignant_melanoma	Substitution - Missense
c.364C>T; p.L122L; 10:69104007-69104007	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.423C>T; p.P141P; 10:69104066-69104066	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.449A>G; p.H150R; 10:69104092-69104092	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.463G>T; p.D155Y; 10:69104106-69104106	oesophagus	carcinoma	Substitution - Missense
c.348G>A; p.M116I; 10:69103991-69103991	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.254G>A; p.R85H; 10:69103897-69103897	breast	carcinoma	Substitution - Missense
c.115C>T; p.R39C; 10:69097119-69097119	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.363A>C; p.Q121H; 10:69104006-69104006	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.115C>T; p.R39C; 10:69097119-69097119	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.115C>T; p.R39C; 10:69097119-69097119	skin	malignant_melanoma	Substitution - Missense
c.115C>T; p.R39C; 10:69097119-69097119	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.455T>C; p.L152S; 10:69104098-69104098	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.228-7A>T; p.?; 10:69103864-69103864	skin; trunk	malignant_melanoma; nodular	Unknown
c.337C>T; p.L113L; 10:69103980-69103980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.172G>A; p.E58K; 10:69097176-69097176	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.154G>A; p.E52K; 10:69097158-69097158	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.203C>G; p.P68R; 10:69097207-69097207	small_intestine	carcinoid-endocrine_tumour	Substitution - Missense
c.361C>T; p.Q121*; 10:69104004-69104004	skin	malignant_melanoma	Substitution - Nonsense
c.293T>C; p.F98S; 10:69103936-69103936	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.293T>C; p.F98S; 10:69103936-69103936	stomach	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]