Entrez Gene

Basic Information
Gene ID	5510
Name	PPP1R7
Synonymous	protein phosphatase 1, regulatory subunit 7;PPP1R7;protein phosphatase 1, regulatory subunit 7
Definition	protein phosphatase 1 regulatory subunit 22\|protein phosphatase 1 regulatory subunit 7\|protein phosphatase 1, regulatory (inhibitor) subunit 7
Position	2q37.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.666A>C; p.K222N; 2:241163353-241163353	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.641T>G; p.F214C; 2:241163328-241163328	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.52+2T>C; p.?; 2:241150549-241150549	stomach	carcinoma; adenocarcinoma	Unknown
c.794A>C; p.E265A; 2:241166416-241166416	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.449C>A; p.S150Y; 2:241160346-241160346	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.232G>T; p.A78S; 2:241157857-241157857	thyroid	other; neoplasm	Substitution - Missense
c.921C>G; p.L307L; 2:241182661-241182661	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.510C>A; p.F170L; 2:241160407-241160407	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.417G>T; p.E139D; 2:241159326-241159326	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.117C>T; p.I39I; 2:241153540-241153540	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.772T>C; p.Y258H; 2:241166394-241166394	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.217delA; p.N73fs*11; 2:241157842-241157842	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.529A>G; p.S177G; 2:241160426-241160426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.529A>G; p.S177G; 2:241160426-241160426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1036G>A; p.A346T; 2:241182776-241182776	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1059C>T; p.I353I; 2:241182799-241182799	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1059C>T; p.I353I; 2:241182799-241182799	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.28C>T; p.Q10*; 2:241150523-241150523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.659T>C; p.I220T; 2:241163346-241163346	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1022G>A; p.R341Q; 2:241182762-241182762	ovary	other; neoplasm	Substitution - Missense
c.943G>A; p.D315N; 2:241182683-241182683	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.67G>A; p.E23K; 2:241153490-241153490	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.654C>T; p.N218N; 2:241163341-241163341	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.603C>T; p.I201I; 2:241163290-241163290	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.531T>C; p.S177S; 2:241160428-241160428	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.220C>G; p.L74V; 2:241157845-241157845	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.848C>T; p.S283L; 2:241169809-241169809	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1046C>T; p.S349F; 2:241182786-241182786	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.493C>T; p.R165*; 2:241160390-241160390	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.760C>G; p.L254V; 2:241166382-241166382	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.810G>A; p.L270L; 2:241166432-241166432	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.831G>T; p.T277T; 2:241169792-241169792	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.589C>T; p.R197C; 2:241160486-241160486	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.589C>T; p.R197C; 2:241160486-241160486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.589C>T; p.R197C; 2:241160486-241160486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.589C>T; p.R197C; 2:241160486-241160486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.40G>A; p.E14K; 2:241150535-241150535	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205A>G; p.M69V; 2:241157830-241157830	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.370G>A; p.E124K; 2:241159279-241159279	breast	carcinoma	Substitution - Missense
c.280T>G; p.F94V; 2:241158526-241158526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.485A>G; p.K162R; 2:241160382-241160382	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.858C>G; p.I286M; 2:241169819-241169819	thyroid	carcinoma	Substitution - Missense
c.316C>T; p.R106C; 2:241159225-241159225	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.316C>T; p.R106C; 2:241159225-241159225	skin	malignant_melanoma	Substitution - Missense
c.787G>T; p.G263C; 2:241166409-241166409	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.212C>T; p.T71I; 2:241157837-241157837	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1048G>A; p.V350M; 2:241182788-241182788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1048G>A; p.V350M; 2:241182788-241182788	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.889G>T; p.E297*; 2:241169850-241169850	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.153G>A; p.G51G; 2:241153576-241153576	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.988C>T; p.R330W; 2:241182728-241182728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.758A>G; p.N253S; 2:241166380-241166380	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.729C>T; p.T243T; 2:241166351-241166351	skin	malignant_melanoma	Substitution - coding silent
c.471C>T; p.I157I; 2:241160368-241160368	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.161G>A; p.R54Q; 2:241153584-241153584	kidney	other; neoplasm	Substitution - Missense
c.557A>G; p.H186R; 2:241160454-241160454	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.989G>A; p.R330Q; 2:241182729-241182729	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.94G>T; p.G32W; 2:241153517-241153517	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.973A>G; p.T325A; 2:241182713-241182713	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.22G>A; p.G8R; 2:241150517-241150517	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.10G>A; p.E4K; 2:241150505-241150505	breast	carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]