| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 55004 |
Name | LAMTOR1 |
Synonymous | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1;LAMTOR1;late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 |
Definition | RhoA activator C11orf59|late endosomal/lysosomal adaptor and MAPK and MTOR activator 1|lipid raft adaptor protein p18|p27Kip1-releasing factor from RhoA|p27kip1 releasing factor from RhoA|protein associated with DRMs and endosomes|ragulator complex protei |
Position | 11q13.4 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.272G>A; p.R91H; 11:72098410-72098410 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.55C>T; p.R19W; 11:72099244-72099244 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.55C>T; p.R19W; 11:72099244-72099244 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.251G>A; p.R84H; 11:72098796-72098796 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.82C>A; p.P28T; 11:72099217-72099217 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.196A>T; p.I66F; 11:72098851-72098851 |
liver | carcinoma | Substitution - Missense |
c.196A>T; p.I66F; 11:72098851-72098851 |
liver | carcinoma | Substitution - Missense |
c.271C>T; p.R91C; 11:72098411-72098411 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.327G>A; p.P109P; 11:72098355-72098355 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.360C>T; p.A120A; 11:72098322-72098322 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.303T>C; p.H101H; 11:72098379-72098379 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.205T>A; p.S69T; 11:72098842-72098842 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.205T>A; p.S69T; 11:72098842-72098842 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.24G>C; p.E8D; 11:72103201-72103201 |
cervix | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.75T>C; p.P25P; 11:72099224-72099224 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |