Entrez Gene

Basic Information
Gene ID	54874
Name	FNBP1L
Synonymous	formin binding protein 1-like;FNBP1L;formin binding protein 1-like
Definition	formin-binding protein 1-like\|toca-1\|transducer of Cdc42-dependent actin assembly 1\|transducer of Cdc42-dependent actin assembly protein 1
Position	1p22.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.995C>T; p.P332L; 1:93544111-93544111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.537G>A; p.T179T; 1:93530781-93530781	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1536G>T; p.E512D; 1:93551005-93551005	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1414G>A; p.E472K; 1:93549363-93549363	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1432C>A; p.P478T; 1:93549381-93549381	oesophagus	carcinoma	Substitution - Missense
c.1196A>G; p.N399S; 1:93546937-93546937	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1207C>A; p.L403I; 1:93546948-93546948	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.934delA; p.T313fs*3; 1:93534852-93534852	autonomic_ganglia	neuroblastoma	Deletion - Frameshift
c.772G>T; p.V258F; 1:93533054-93533054	pancreas	carcinoma	Substitution - Missense
c.1628A>G; p.N543S; 1:93551097-93551097	kidney	other; neoplasm	Substitution - Missense
c.972C>T; p.L324L; 1:93534890-93534890	large_intestine; rectum	NS	Substitution - coding silent
c.1083G>A; p.Q361Q; 1:93544199-93544199	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.713G>A; p.R238H; 1:93532995-93532995	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1484A>G; p.N495S; 1:93550953-93550953	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.164C>T; p.P55L; 1:93522105-93522105	skin	malignant_melanoma	Substitution - Missense
c.1185G>A; p.E395E; 1:93546926-93546926	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.850G>T; p.E284*; 1:93534768-93534768	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1533G>T; p.E511D; 1:93551002-93551002	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1359C>T; p.N453N; 1:93549308-93549308	skin	malignant_melanoma	Substitution - coding silent
c.997G>A; p.A333T; 1:93544113-93544113	breast	carcinoma	Substitution - Missense
c.119A>T; p.Q40L; 1:93499562-93499562	oesophagus	carcinoma	Substitution - Missense
c.1164T>C; p.S388S; 1:93546905-93546905	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.33C>T; p.F11F; 1:93499476-93499476	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.33C>T; p.F11F; 1:93499476-93499476	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.343-3C>T; p.?; 1:93524258-93524258	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1105G>A; p.A369T; 1:93546846-93546846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.287G>A; p.R96K; 1:93523436-93523436	skin	malignant_melanoma	Substitution - Missense
c.1132G>C; p.E378Q; 1:93546873-93546873	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1380C>T; p.P460P; 1:93549329-93549329	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.538C>T; p.H180Y; 1:93530782-93530782	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.513C>T; p.A171A; 1:93530757-93530757	skin	malignant_melanoma	Substitution - coding silent
c.753G>C; p.M251I; 1:93533035-93533035	breast	carcinoma	Substitution - Missense
c.1609G>A; p.D537N; 1:93551078-93551078	breast	carcinoma	Substitution - Missense
c.57A>T; p.Q19H; 1:93499500-93499500	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.919G>T; p.G307W; 1:93534837-93534837	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.170G>T; p.R57L; 1:93522111-93522111	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.84T>C; p.Y28Y; 1:93499527-93499527	thyroid	carcinoma	Substitution - coding silent
c.282G>A; p.A94A; 1:93523431-93523431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.533G>A; p.R178H; 1:93530777-93530777	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.533G>A; p.R178H; 1:93530777-93530777	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.193C>T; p.R65W; 1:93522134-93522134	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.193C>T; p.R65W; 1:93522134-93522134	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.193C>T; p.R65W; 1:93522134-93522134	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.467G>T; p.R156I; 1:93529713-93529713	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.936A>C; p.K312N; 1:93534854-93534854	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.136T>A; p.L46M; 1:93499579-93499579	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1393C>T; p.H465Y; 1:93549342-93549342	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.256C>T; p.R86*; 1:93523405-93523405	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.994C>A; p.P332T; 1:93544110-93544110	large_intestine; colon	NS	Substitution - Missense
c.1226A>G; p.K409R; 1:93546967-93546967	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.824T>G; p.F275C; 1:93534742-93534742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.991-1G>T; p.?; 1:93544106-93544106	kidney	other; neoplasm	Unknown
c.1370G>A; p.R457H; 1:93549319-93549319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.778G>A; p.E260K; 1:93533060-93533060	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.390G>C; p.W130C; 1:93524308-93524308	breast	carcinoma	Substitution - Missense
c.72C>A; p.F24L; 1:93499515-93499515	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1424A>C; p.D475A; 1:93549373-93549373	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1183G>A; p.E395K; 1:93546924-93546924	skin	malignant_melanoma	Substitution - Missense
c.907delA; p.K303fs*13; 1:93534825-93534825	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.84T>A; p.Y28*; 1:93499527-93499527	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1519C>T; p.L507F; 1:93550988-93550988	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]