| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5464 |
Name | PPA1 |
Synonymous | pyrophosphatase (inorganic) 1;PPA1;pyrophosphatase (inorganic) 1 |
Definition | PPase|cytosolic inorganic pyrophosphatase|diphosphate phosphohydrolase|epididymis secretory sperm binding protein Li 66p|inorganic diphosphatase|inorganic pyrophosphatase|inorganic pyrophosphatase 1|pyrophosphatase 1|pyrophosphate phospho-hydrolase |
Position | 10q11.1-q24 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.159G>T; p.W53C; 10:70218782-70218782 |
breast | carcinoma | Substitution - Missense |
c.704C>T; p.T235M; 10:70209226-70209226 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.106C>T; p.P36S; 10:70230358-70230358 |
skin | malignant_melanoma | Substitution - Missense |
c.614C>T; p.A205V; 10:70209583-70209583 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.550G>A; p.E184K; 10:70209647-70209647 |
breast | carcinoma | Substitution - Missense |
c.372A>G; p.E124E; 10:70214512-70214512 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.373A>G; p.I125V; 10:70214511-70214511 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.373A>G; p.I125V; 10:70214511-70214511 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.385G>T; p.V129L; 10:70213589-70213589 |
stomach | carcinoma; diffuse_adenocarcinoma | Substitution - Missense |
c.286G>A; p.A96T; 10:70217823-70217823 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.539C>A; p.P180H; 10:70209658-70209658 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.277A>C; p.N93H; 10:70217832-70217832 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.615G>T; p.A205A; 10:70209582-70209582 |
prostate | adenoma | Substitution - coding silent |
c.171A>C; p.K57N; 10:70218770-70218770 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.615G>T; p.A205A; 10:70209582-70209582 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.615G>T; p.A205A; 10:70209582-70209582 |
thyroid | other; neoplasm | Substitution - coding silent |
c.150A>G; p.V50V; 10:70218791-70218791 |
liver | carcinoma | Substitution - coding silent |
c.412G>A; p.V138M; 10:70213562-70213562 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.369T>G; p.C123W; 10:70214515-70214515 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.574A>T; p.R192W; 10:70209623-70209623 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.838G>A; p.V280M; 10:70204873-70204873 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.631A>G; p.K211E; 10:70209566-70209566 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.433G>A; p.A145T; 10:70213541-70213541 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.823A>G; p.T275A; 10:70204888-70204888 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.715G>A; p.G239R; 10:70209215-70209215 |
skin; extremity | malignant_melanoma | Substitution - Missense |
c.624A>T; p.A208A; 10:70209573-70209573 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.246G>A; p.A82A; 10:70217863-70217863 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.246G>A; p.A82A; 10:70217863-70217863 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.725G>T; p.C242F; 10:70209205-70209205 |
skin; hand | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.457G>A; p.D153N; 10:70213517-70213517 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.457G>A; p.D153N; 10:70213517-70213517 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.768T>G; p.P256P; 10:70206291-70206291 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - coding silent |
c.839-8G>A; p.?; 10:70203194-70203194 |
liver | carcinoma | Unknown |
c.149T>C; p.V50A; 10:70218792-70218792 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.161C>G; p.S54C; 10:70218780-70218780 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.235C>T; p.R79C; 10:70217874-70217874 |
breast | carcinoma | Substitution - Missense |
c.701A>G; p.K234R; 10:70209229-70209229 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.148G>T; p.V50L; 10:70218793-70218793 |
breast | carcinoma | Substitution - Missense |